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All Journal Jurnal Dedikasi Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) UNEJ e-Proceeding Martabe : Jurnal Pengabdian Kepada Masyarakat Food Science and Technology Journal (Foodscitech) Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Jurnal EduHealth
Engrid Juni Astuti
Program Studi Farmasi Fakultas Ilmu Kesehatan Universitas Muhammadiyah Malang
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Veterinary

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EDUKASI DAGUSIBU DAN PENGENALAN APOTEKER CILIK (APOCIL) Engrid Juni Astuti; Ika Ratna Hidayati
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 4, No 3 (2021): Martabe : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v4i3.984-989

Abstract

Peran Apoteker sebagai profesi yang terkait dengan obat sangat penting terutama dalam memberikan edukasi tentang obat-obatan. Kegiatan pengenalan tentang obat  sejak dini sangat diperlukan guna memperkenalkan jati diri apoteker dan tentang obat kepada siswa sekolah Dasar. Edukasi terkait obat yang akan dilakukan di sekolah dasar bertemakan “Pengenalan Apocil dan Dagusibu” di Sekolah Dasar. Minimnya pengetahuan tentang Obat di masyarakat dimulai dengan pemberian pengetahuan sejak dini pada siswa sekolah dasar karena mereka yang nantinya akan menjadi remaja dan mengurangi penyalahgunaan obat di masyarakat seperti yang saat ini banyak sekali terjadi pada siswa sekolah menengah atas ataupun mahasiswa. Target dari kegiatan ini adalah siswa kelas 4,5, dan 6 MI Assalafiyah agar memperoleh wawasan tentang obat secara benar. Kegiatan dilakukan dengan cara pembelajaran online menggunakan beberapa platform, diantaranya : grup whatsapp kelas, google form, dan link youtube. Sebelum diberikan materi maka dilakukan pretes dan postest dari masing-masing materi, ada 2 materi yang diberikan yaitu pengenalan profesi Apoteker, cara penggunaan obat yang benar, dan edukasi DaGuSiB.  Selain itu pengabdian ini diharapkan dapat memotivasi siswa-siswa agar memiliki kesadaran untuk dapat mengawasi teman-teman dikelas lain dalam menggunakan obat dengan benar. Dari hasil kegiatan didapatkan bahwa siswa antusias dalam mengikuti kegiatan pengabdian masyarakat meskipun tidak terjadi peningkatan nilai rata-rata dari pretes (75,8) dan postes (75,3). 
PEMANFAATAN SENYAWA METABOLIT SEKUNDER KAWISTA (Limonia acidissima) UNTUK PENGELOLAAN DIABETES: TINJAUAN ANALISIS JEJARING FARMAKOLOGI Hentu, Dina Siti Rahma M.; Muchlisin, M. Artabah; Jamil, Ahmad Shobrun; Astuti, Engrid Juni; Rafikayanti, Agustin
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 9 No 1 (2024): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jpx.v9i1.6964

Abstract

This study aims to explore the potential of secondary metabolite compounds from the kawista plant (Limonia acidissima) as antidiabetic agents through an in silico approach. We utilized pharmacological network analysis and analysis of the most important proteins to identify potential protein targets and signaling pathways involved in diabetes regulation. The analysis revealed that secondary metabolite compounds from kawista have the potential to affect various crucial aspects of glucose and lipid metabolism in the body, including through interactions with key proteins such as AKT1. These findings provide new insights into the development of additional therapies for diabetes treatment, and demonstrate the potential of in silico methods in accelerating the discovery and development of new drugs.
Level of anxiety and internal tryout evaluation of the national objective structured clinical examinations (OSCE) results for pharmacy students Astuti, Engrid Juni; Hidayati, Ika Ratna
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 7 No. 2 (2022)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v7i2.35340

Abstract

OSCE (Objective Structured Clinical Examination) for pharmacist profession students is currently one of the measuring tools for success in competency exams to test victory in learning the Pharmacist Profession, in addition to the MCQ (Cognitive Based Test) method which is carried out in the form of CBT (Computer Based-Test). The Pharmacist Profession Study Program at the University of Muhammadiyah Malang (UMM) currently has professional pharmacist students and conducted a national tryout test for batch 2 students. In contrast, these students have never received training for the OSCE exam before. This study was conducted to evaluate the internal tryout on the results of the national OSCE score for Pharmacist students at the University of Muhammadiyah Malang” in batch 3 compared to batch 2, which had not done an internal tryout. In addition, an anxiety test was conducted on students taking the OSCE exam to get the degree of anxiety students taking the exam. From the study results, the anxiety level of the 2nd and 3rd batch students when facing the national OSCE exam was moderately anxious. Implementing the internal tryout had significant effects on the passing rate of the 3rd batch of students in the national OSCE exam.
Potential Activity Of Secondary Metabolites Of Kawista (Limonia Acidissima) As Neurodegenerative Diseases : A Network Pharmacology Approaches Dina Siti Rahma M. Hentu; Muchlisin, M. Artabah; Jamil, Ahmad Shobrun; Astuti, Engrid Juni; Rafikayanti, Agustin
Jurnal EduHealth Vol. 15 No. 02 (2024): Jurnal eduHealt, Edition April - June , 2024
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Kawista (Limonia acidissima) is a tropical plant traditionally used in South and Southeast Asian medicine, and its known for its rich nutritional profile and bioactive compounds. This study explores the therapeutic potential of kawista for neurodegenerative diseases. This study aims to investigate the potential of kawista in managing neurodegenerative through a pharmacological network approach. Proteins that can interact with secondary metabolites of kawista were predicted using SwissTargetPrediction, proteins related to neurodegenerative were obtained from GeneCards. The intersecting results were analyzed using STRING with GO (Gene Ontology) and KEGG (Kyoto Encyclopedia of Genes and Genomes) enrichment methods. From 47 secondary metabolites of kawista, 218 neuro-related proteins was identified potentially interacting with kawista's secondary metabolites. Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), and disease-gene association analyses highlighted key biological processes, molecular functions, cellular components, and pathways relevant to neurodegenerative disease mechanisms. The findings suggest that kawista's bioactive compounds could modulate critical pathways and receptor activities, offering insights into developing novel, effective therapies for neurodegenerative disorders. This research providing a scientific basis for kawista-based therapeutic strategies aimed at improving neurodegenerative disease outcomes.
PREPARASI 4-ASETAMIDOFENIL BENZOAT DAN UJI AKTIFITAS ANALGESIK PADA MENCIT (Mus musculus) Muchlisin, M Artabah; Purwanto, Bambang Tri; Astuti, Engrid Juni
Media Farmasi: Jurnal Ilmu Farmasi Vol. 10 No. 2: September 2013
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v10i2.1165

Abstract

> Untuk mengembangkan senyawa turunan acetaminophen baru, dilakukan preparasi 4-acetamidofenil benzoat senyawa. Senyawa ini disintesis dengan mereaksikan dari acetamidofenil dengan benzoil klorida dengan metode Schotten Baumann. Kemurnian senyawa dibuktikan dengan kromatografi lapis tipis (KLT) dan titik lebur. Pada hasil KLT, senyawa yang disintesis memiliki 1 spot dengan tiga eluen yang berbeda dan memiliki rentang titik lebur 171,67-172,67ºC. Sehingga dapat disimpulkan senyawa hasil sintesis murni. Karakterisasi struktur senyawa hasil sintesis dianalisis dengan spektrofotometer UV-VIS, spektrofotometer IR, NMR. Hasil analisis struktural menunjukkan bahwa senyawa hasil sintesis adalah 4 - acetamidofenil benzoat. Uji aktivitas analgesik dilakukan pada tikus menggunakan metode penghambatan nyeri dengan asam asetat glasial 0,6 % sebagai agen penginduksi nyeri. Hasil sintesis 4 - acetamidofenil benzoat memiliki ED50 73,48 mg / kg dan acetaminofen memiliki ED50 68,30 mg / kg. Secara statistik, potensi analgesik 4 - acetamidofenil benzoat sebanding dengan acetaminofen .
Co-Authors Ahmad Shobrun Jamil Akhmad Aminur Rizqia Bambang Tri Purwanto Dian Ermawati Dina Siti Rahma M. Hentu Hentu, Dina Siti Rahma M. Hidajah Rachmawati Ika Ratna Hidayati Ilham, Roha Fakhri Naufal Januar Rahman Juni Ekowati M. Artabah Muchlisin Muchlisin, M. Artabah Purwanto, Septiana Tita Puspitasari, Chenchen Rafikayanti, Agustin Rahman, Januar Rahmana Emran Kartasasmita Riesta Prima Harinastitic Rika, Wenni Fista Roha Fakhri Naufal Ilham Sovia Aprina Basukia Yesica, Yeni