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Identifikasi Endoparasit Tikus yang Berpotensi Zoonosis di Tiga Desa Kabupaten Bogor Jawa Barat Astuty, Hendri; Winita, Rawina; Firmansyah, Nurhadi Eko; Lestiani, Budi; Zamziar, Hanny
Anakes : Jurnal Ilmiah Analis Kesehatan Vol. 10 No. 1 (2024): ANAKES: Jurnal Ilmiah Analis Kesehatan
Publisher : Universitas Mohammad Husni Thamrin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37012/anakes.v10i1.2094

Rats (Rattus sp) are rodents that play an important role in public health as zoonoses. In the world there are 29 rodent and 171 species of the Muridae. Rats can potentially be a reservoir of infectious diseases such as from Toxocara, Capillaria hepatica and protozoan groups. Among the worms found in the intestines of rats can infect humans and animals including Echinostomes cause severe gastrointestinal, epigastric or abdominal pain accompanied by diarrhea, fatigue and malnutrition. The purpose of this study was to determine the type of rat endoparasite that has the potential to be zoonotic in the residential environment of residential of 3 villages in Bogor Regency, namely Batu City, Mekar Jaya and Parakan. This type of research is Cross-sectional approach. Sampling using random sampling technique by collecting various rat habitats as many as 100 traps. The trap success value is 11%. Rat that were caught for 3 days were 33 consisting of Rattus tanezumi (15.15%), R. norvegicus (18.2%), R.tiomanicus (12.1%), Bandicota indica (24.2%) and Mus musculus (12.1%). Microscopic results of endoparasite found hookworm eggs and larvae, Entamoeba histolytica cyst, E.coli cyst, Chilomatrix mesnili, Hymenolepis diminuta, H.nana, Trychostrongylus sp, Blastocystis hominis . The community around location should always pay attention to sanitation and maintain cleanliness to avoid the risk transmission of diseases caused rats Keyword: Endoparasite, Zoonoses, Rat

Potensi Propolis dan Kombinasi Dengan Klorokuin Sebagai Antimalaria Pada Mencit (Mus Musculus) yang Terinfeksi Plasmodium berghei Astuty, Hendri; Farhan, Muhamad; Winita, Rawina
Anakes : Jurnal Ilmiah Analis Kesehatan Vol. 11 No. 1 (2025): ANAKES: Jurnal Ilmiah Analis Kesehatan
Publisher : Universitas Mohammad Husni Thamrin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37012/anakes.v11i1.2610

Malaria is still a public health problem both in Southeast Asia and other regions of the world. The emergence of resistance to several malaria drugs, including chloroquine. With the increase in malaria resistance, including chloroquine. With the increase in malaria drug resistance, many studies have been conducted to find new antimalarial compounds. One of them is propolis which contains luteolin 7-O glucoside which can inhibit the biosynthesis of parasitic type 2 fatty acids and chalcone can inhibit the hemolysis process. This study aims to examine the therapeutic potential of propolis single and combination with chloroquine in male Mus musculus infected with Plasmodium berghei. The single propolis tested were 30 mg/kgBW, 60 mg/kgBW and a combination of propolis. This study is an experimental laboratory study with a post-test control group-only design. Comparison of parasitemia density with the 4-day suppression test method in all treatment groups with the Kruskal-Wallis test found a p-value <0.001. The results study showed that single propolis at a dose of 30 mg/kg BW was better than a dose of 60 mg/kg BW. Combination therapy between propolis and chloroquine at doses of 30 mg/kg BB and 60 mg/kg BB had significant results. The conclusion of this study shows that combination therapy of propolis at a dose of 30 mg/kg WB or a dose of 60 mg/kg BB with chloroquine has better antimalarial potential, so propolis is synergistic with chloroquine as an antimalarial. Keywords: Propolis , Chloroquine, Plasmodium berghei, Parasitemia

Identifikasi Endoparasit Tikus yang Berpotensi Zoonosis di Tiga Desa Kabupaten Bogor Jawa Barat Astuty, Hendri; Winita, Rawina; Firmansyah, Nurhadi Eko; Lestiani, Budi; Zamziar, Hanny
Anakes : Jurnal Ilmiah Analis Kesehatan Vol. 10 No. 1 (2024): ANAKES: Jurnal Ilmiah Analis Kesehatan
Publisher : Universitas Mohammad Husni Thamrin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37012/anakes.v10i1.2094

Rats (Rattus sp) are rodents that play an important role in public health as zoonoses. In the world there are 29 rodent and 171 species of the Muridae. Rats can potentially be a reservoir of infectious diseases such as from Toxocara, Capillaria hepatica and protozoan groups. Among the worms found in the intestines of rats can infect humans and animals including Echinostomes cause severe gastrointestinal, epigastric or abdominal pain accompanied by diarrhea, fatigue and malnutrition. The purpose of this study was to determine the type of rat endoparasite that has the potential to be zoonotic in the residential environment of residential of 3 villages in Bogor Regency, namely Batu City, Mekar Jaya and Parakan. This type of research is Cross-sectional approach. Sampling using random sampling technique by collecting various rat habitats as many as 100 traps. The trap success value is 11%. Rat that were caught for 3 days were 33 consisting of Rattus tanezumi (15.15%), R. norvegicus (18.2%), R.tiomanicus (12.1%), Bandicota indica (24.2%) and Mus musculus (12.1%). Microscopic results of endoparasite found hookworm eggs and larvae, Entamoeba histolytica cyst, E.coli cyst, Chilomatrix mesnili, Hymenolepis diminuta, H.nana, Trychostrongylus sp, Blastocystis hominis . The community around location should always pay attention to sanitation and maintain cleanliness to avoid the risk transmission of diseases caused rats Keyword: Endoparasite, Zoonoses, Rat

Potensi Propolis dan Kombinasi Dengan Klorokuin Sebagai Antimalaria Pada Mencit (Mus Musculus) yang Terinfeksi Plasmodium berghei Astuty, Hendri; Farhan, Muhamad; Winita, Rawina
Anakes : Jurnal Ilmiah Analis Kesehatan Vol. 11 No. 1 (2025): ANAKES: Jurnal Ilmiah Analis Kesehatan
Publisher : Universitas Mohammad Husni Thamrin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37012/anakes.v11i1.2610

Malaria is still a public health problem both in Southeast Asia and other regions of the world. The emergence of resistance to several malaria drugs, including chloroquine. With the increase in malaria resistance, including chloroquine. With the increase in malaria drug resistance, many studies have been conducted to find new antimalarial compounds. One of them is propolis which contains luteolin 7-O glucoside which can inhibit the biosynthesis of parasitic type 2 fatty acids and chalcone can inhibit the hemolysis process. This study aims to examine the therapeutic potential of propolis single and combination with chloroquine in male Mus musculus infected with Plasmodium berghei. The single propolis tested were 30 mg/kgBW, 60 mg/kgBW and a combination of propolis. This study is an experimental laboratory study with a post-test control group-only design. Comparison of parasitemia density with the 4-day suppression test method in all treatment groups with the Kruskal-Wallis test found a p-value <0.001. The results study showed that single propolis at a dose of 30 mg/kg BW was better than a dose of 60 mg/kg BW. Combination therapy between propolis and chloroquine at doses of 30 mg/kg BB and 60 mg/kg BB had significant results. The conclusion of this study shows that combination therapy of propolis at a dose of 30 mg/kg WB or a dose of 60 mg/kg BB with chloroquine has better antimalarial potential, so propolis is synergistic with chloroquine as an antimalarial. Keywords: Propolis , Chloroquine, Plasmodium berghei, Parasitemia

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