Suharyo Hadisaputro
Universitas Diponegoro Semarang

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SIDE EFFECTS FACTORS AFFECT THE COMPLIANCE OF ANTIRETROVIRAL TREATMENT IN PLWHS: STUDY OF UNDATA DISTRICT GENERAL HOSPITAL, PALU Defi - -; Suharyo Hadisaputro; Muchlis Achsan U.Sofro
VISIKES: Jurnal Kesehatan Masyarakat Vol 19, No 01 (2020)
Publisher : Dian Nuswantoro Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (347.897 KB) | DOI: 10.33633/visikes.v19i01.3759

Abstract

Background : Antiretroviral treatment currently starts in all people with HIV / AIDS, namely children, adolescents, and adults regardless of clinical stage or CD4 cell count. This is an effort to reduce the time needed to start ARV therapy after being diagnosed with HIV but taking into account the readiness of people with HIV / AIDS. Objective: To prove the age, sex, occupation, and history of side effects to adherence to ARV treatment in PLWHA.Method: Quantitative approach using the type of Case-Control research. The sample in this study was 35 cases and 35 controls. The sampling technique in this study was done by consecutive sampling, collecting data obtained from interviews using research instruments namely questionnaires and patient medical record reports. Statistical analysis using SPSS 25 with a chi-square test. Results: Proven to influence the adherence of ARV treatment in PLWHA were a history of side effects (p = 0.002). those not proven to affect the adherence of ARV treatment in PLWHA were Age (p = 0.189) Gender (p = 1.00) Occupation (p = 0.297). Conclusion: A history of side effects has been shown to influence ARV treatment.Keywords: HIV/AIDS, ARVs, Compliance
Pengaruh akupresur perikardium 6 terhadap mual muntah kehamilan kurang 16 minggu: Studi kasus di Puskesmas Mantrijeron dan Mergangsan Yogyakarta Nur Djanah; Suharyo Hadisaputro; Triana Sri Hardjanti
Jurnal Kesehatan Ibu dan Anak Vol. 5 No. 1 (2014): Juli
Publisher : Poltekkes Kemenkes Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29238/kia.v5i1.393

Abstract

Nausea and vomiting in pregnancy is a common problem, which can be serious for both mother and baby. More than half (50-90%) of pregnant women experiencing nausea vomiting. Numerous attempts have been made to reduce the nausea vomiting with pharmacological and nonpharmacological approaches. Acupressure Pericardium 6 is one of the non-pharmacological approach, which is related closely to acupuncture, is considered as a key point in reducing the symptoms of nausea and vomiting, but some studies show contradictory results. The purpose of this research was to describes the effect of acupressure Pericardium 6 to decrease the frequency of nausea vomiting of pregnancy less 16 weeks.The design used was randomized pre-post test control group design. Total sample 33 consists of 17 intervention group and 16 control group, who meets the criteria of inclusion and exclusion. The mother’s age, gravidity, obesity levels and hiperemesis gravidarum history matched between groups. The intervention group were given a treatment of acupressure on acupoint Pericardium 6, while the control group acupressure on three fingers on top of acupoint Pericardium 6, it was done every 5 minutes for four days. There are significant differences on decreases of the duration of nausea (p = 0.002) and episodes of nausea vomiting (p = 0,015) between the intervention group and control group after intervention, while episodes of retching vomiting there are no significant differences (p = 0,159). The conclusion was that the acupressure Pericardium 6 can decreases of the frequency of nausea vomiting of pregnancy. Acupressure Pericardium 6 can be applied as a non-pharmacological therapy to decrease frequency of nausea vomiting in pregnancy less than 16 weeks.
Pengaruh Kombinasi Metformin dan Ekstrak Air Meniran (Phyllanthus niruri Linn.) terhadap Perbaikan Status Obesitas Tikus Sprague dawley Jantan Ai Sri Kosnayani; Edi Dharmana; Suharyo Hadisaputro; Ignatius Riwanto
Amerta Nutrition Vol. 5 No. 1 (2021): AMERTA NUTRITION
Publisher : Universitas Airlangga, Kampus C, Mulyorejo, Surabaya-60115, East Java, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v5i1.2021.52-58

Abstract

Latar Belakang: Perubahan gaya hidup dan pola makan menyebabkan tingginya angka kejadian obesitas di seluruh dunia yaitu 13% padat tahun 2016. Perbaikan status obesitas dapat dilakukan melalui jalur farmakologik ataupun non farmakologik. Metformin dan meniran (Phyllanthus niruri Linn.) mempunyai fungsi untuk menurunkan penyerapan asupan makanan.Tujuan: menganalisis pengaruh kombinasi metformin dan ekstrak air meniran (Phyllanthus niruri Linn.) terhadap perbaikan status obesitas tikus Sprague Dawley jantan.Metode: multigroup time series design.  Dua puluh empat ekor tikus dibuat obesitas dengan cara diberi pakan tambahan lemak sapi cair dan fruktosa terhadap pakan dasar AIN93G selama 5 minggu. Obesitas ditentukan dengan indeks Lee > 300. Sampel dikelompokkan menjadi 4 kelompok, kelompok 1 diberi metformin 45 mg/kg BB/hari, kelompok 2 diberi ekstrak air meniran 400 mg/kg BB/hari, kelompok 3 diberi kombinasi keduanya, dan kelompok 4 kontrol.Hasil: Selama penelitian ada perbedaan berat pakan dan asupan kalori  pada setiap kelompok perlakuan. Setelah 28 hari perlakuan ada perbedaan kenaikan berat badan dan perubahan indeks Lee antara ketiga kelompok perlakuan (ρ < 0,05), walaupun indeks Lee > 300.Kesimpulan: pemberian kombinasi ekstrak air meniran dan metformin dapat mengendalikan kenaikan berat badan dan menurunkan indeks Lee.
POTENSI KEANEKARAGAMAN UMUR NYAMUK Culex quinquefasciatus SEBAGAI VEKTOR FILARIASIS DI DAERAH ENDEMIS KOTA PEKALONGAN Abdul Ghofur; Suharyo Hadisaputro; Sayono Sayono; Argo Ganda Gumilar
Jurnal Kesehatan Kusuma Husada Vol. 15 No. 1, Januari 2024
Publisher : Universitas Kusuma Husada Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34035/jk.v15i1.1213

Abstract

Filariasis adalah penyakit menular menahun yang disebabkan oleh cacing filaria dan ditularkan melalui nyamuk (vector borne disiese). WHO menetapkan kesepakatan global sebagai upaya untuk mengeliminasi filariasis pada tahun 2020 melalui Global Programme to Eliminate Lymphatic Filariasis (GPELF), tetapi sampai tahun 2023 di Kelurahan Jenggot Kota Pekalongan masih menjadi daerah endemis filariasis dengan ditemukannya kasus baru. Nyamuk berpotensi sebagai vektor filriasis apabila memenuhi persyaratan populasi spesies yang bersangkutan secara umum mempunyai umur cukup untuk menjadi vektor masa inkubasi eksternal dari filaria. Tujuan penelitian ini adalah untuk mengetahui umur nyamuk Culex quinquefasciatus sebagai vektor filariasis di daerah Endemis Kelurahan Jenggot Kota Pekalongan. Cx. quinquefasciatus dipilih karena menjadi spesies terbanyak di daerah penelitian dan berpotensi menjadi vektor filariasis. Desain penelitian ini adalah deskriptif kuantitatif dengan menggunakan 200 sampel nyamuk betina dengan metode dilatasi ovarium. yaitu dengan membedah ovarium nyamuk untuk memeriksa parousitasnya. Selanjutnya, jumlah dilatasi dikalikan dengan siklus gonotropik nyamuk, sehingga diperoleh spesies vektor yang berpotensi sebagai penular penyakit bila dikaitkan dengan umur siklus hidup ekstrinsik parasit. Hasil penelitian didapatkan rata – rata umur nyamuk Cx. quinquefasciatus adalah 17.2 hari sedangkan masa inkubasi ekstrinsik filaria dari L1 sampai L3 adalah 10-13 hari. Dari hasil penelitian dapat disimpulkan bahwa nyamuk Cx. quinquefasciatus memiliki umur yang berpotensi menjadi vektor filariasis. Filariasis is a chronic infectious disease caused by filarial worms and transmitted through mosquitoes (vector borne disease). WHO established a global agreement as an effort to eliminate filariasis by 2020 through the Global Program to Eliminate Lymphatic Filariasis (GPELF), but until 2023 Jenggot Village, Pekalongan City, is still an endemic area for filariasis with the discovery of new cases. Mosquitoes have the potential to be vectors of filariasis if they meet the requirements for the population of the species concerned to generally have sufficient age to become a vector for the external incubation period of filariasis. The aim of this research is to determine the age of the Culex quinquefasciatus mosquito as a filariasis vector in the endemic area of Jenggot Village, Pekalongan City. Cx. quinquefasciatus was chosen because it is the most abundant species in the study area and has the potential to be a filariasis vector. The design of this research was descriptive quantitative using 200 samples of female mosquitoes using the ovarian dilatation method. namely by dissecting the mosquito's ovary to check its parousity. Next, the number of dilations is multiplied by the mosquito's gonotrophic cycle, to obtain a vector species that has the potential to transmit disease when related to the age of the parasite's extrinsic life cycle. The research results showed that the average lifespan of Cx mosquitoes. quinquefasciatus is 17.2 days while the incubation period for extrinsic filaria from L1 to L3 is 10-13 days. From the research results it can be concluded that the mosquito Cx. quinquefasciatus has the potential to become a filariasis vector.