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All Journal Medical Journal of Indonesia Makara Journal of Science
Sofna D.S. Banjarnahor
Pusat Penelitian Kimia-Lembaga Ilmu Pengetahuan Indonesia (LIPI) Kawasan PUSPIPTEK, Tangerang Selatan 15314
Medicine & Pharmacology

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Antioxidant properties of flavonoids Banjarnahor, Sofna D.S.; Artanti, Nina
Medical Journal of Indonesia Vol 23, No 4 (2014): November
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (701.645 KB) | DOI: 10.13181/mji.v23i4.1015

Abstract

Flavonoids represent a remarkable group of plant secondary metabolites and have long been used as traditional medicines with scientifically proven pharmacological benefits. They serve vast-ranging medicinal activities that may lead drug discovery with novel and potential therapeutic evidence. Latest research magnifies primarily functional activity of flavonoids as antioxidant against oxidative stress. This review enlightens the prospective role of flavonoids as antioxidant.
PENENTUAN LD50 DAUN CINCO (Cyclea barbata Miers.) PADA MENCIT Angelina, Marissa; Hartati, Sri; Dewijanti, Indah D; Banjarnahor, Sofna D.S.; Meilawati, Lia
Makara Journal of Science Vol. 12, No. 1
Publisher : UI Scholars Hub

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Abstract

LD50 of Cinco (Cyclea barbata Miers.) Leaf on Mice. The acute toxicity of ethanol extract of Cyclea barbata Miers. (Cb) leaves has been carried out on mice. The extract was administered by oral route in 4 different doses, i.e. 300 mg/kg BW, 1500 mg/kg BW, 3000 mg/kg BW, 30000 mg/kg BW. The toxic effect of the extract were evaluated by observation of behaviour, spinal reflexes, central nervous system, urination, and defecation, and also number of dead animal. The observation period lasted for 14 days. The results showed that up to 30000 mg/kg BW, the test material did not cause any significant toxic effects. The LD50 of the cyclea barbata Miers. leaves on mice was found to be more than 30000 mg/kg BW
Co-Authors Indah D Dewijanti, Indah D Lia Meilawati Marissa Angelina Nina Artanti Sri Hartati