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All Journal International Journal of Public Health Science (IJPHS) Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Journal of Medical Physics and Biophysics JBN (Jurnal Bedah Nasional) JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Berita Kedokteran Masyarakat Journal of Global Pharma Technology The Hip and Knee Journal Indonesian Journal of Biomedicine and Clinical Sciences
Rahadyan Magetsari
Division Of Orthopaedics And Traumatology, Department Of Surgery, Faculty Of Medicine, Public Health And Nursing, Universitas Gadjah Mada
Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Physics Public Health

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Journal : Journal of Global Pharma Technology

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Primitive Neuroectodermal Tumor (PNET) at the Level of Thoracic Spine: A Case Report Magetsari Rahadyan
Journal of Global Pharma Technology Volume 11 Issue 01.
Publisher : Journal of Global Pharma Technology

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Introduction Primitive neuroectodermal tumors (PNET) are malignant tumors thought to arise from the neural ectoderm and comprise of undifferentiated small round cells that affect soft tissue and bone. These tumors occur primarily in children and adolescents (thirteen to sixteen years old), with a tendency to recur quickly and metastasize especially to lungs, bone marrow, brain and lymph nodes. PNET are uncommon malignancies that are increasingly reported in the literature and located in the spine are extremely rare. In this study we present a case of 14 years old girl with PNET of the thoracic spine which recur after initial resection. Case Report a 14 years old girl presented with low back pain and progressive weakness of both of lower limbs of three months duration. On physical examination, motor and sensory function was lost, motoric strength in the lower limbs was grade 1/5 with hypoesthesia below L1 level. Magnetic resonance imaging (MRI) of the spine showed burst pathologic fracture of the 12th thoracic spine with suspicious malignant lesion in the 12th thoracic spine. Initially the condition was treated with laminectomy, decompression, stabilization and open biopsy. Histopathology and immunohistochemistry of the lesion revealed the diagnosis of PNET. During the early postoperative course, she had instance neurological recovery and was able to walk unassisted. But, 1 month later the neurologic deficit recurred and she was treated with extended laminectomy with tumor debulking. Then the patient received chemotherapy and planned for radiotherapy. Conclusion Primitive neuroectodermal tumors (PNET) are extremely rare and are aggressive with poor outcomes. Good modalities play a significant role in the identification of the feasibility of surgical excision of the tumors, detection of distant metastasis, and evaluation of the efficacy of therapeutic interventions.Keywords:  Primitive neuroectodermal tumor (PNET), Malignant Tumor, Rare Tumor, Spinal Tumor.
Clinical Correlates of the Severity of Diabetic Foot Ulcers Rahadyan Magetsari; Meirizal Hasan; Yossie Atyandhari
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
Publisher : Journal of Global Pharma Technology

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OBJECTIVE Severe diabetic foot ulcer leads to amputation and is associated with higher risk of mortality. The purpose of this study is to identify clinical correlates of severe diabetic foot ulcers. METHODS The design of the study was cross-sectional survey of medical records on patients treated in Sardjito Hospital from 1 January to 31 July, 2014. Severe foot ulcer was measured as grade 4 and 5 according to Wagner classification. ABI (Ankle Brachial Index) to estimate blood flow to lower extremities and Semmes-Weinstein test using monofilament to detect neuropathy, classified as positive or negative, were done in all patients. HbA1C, serum sodium and creatinine levels were measured during the latest hospital visit. RESULTS The results of this study showed that 77 (36.5%) among 211 patients had severe foot ulcers (grade 4 and 5, Wagner classification). ABI and Semmes-Weinstein monofilament test failed to predict severity of diabetic foot ulcers. HbA1c increased the odds of severe ulcers while higher serum sodium level and higher diastolic blood pressure protected patients against severe ulcers. CONCLUSION Better glycemic control and caution against excessive reduction of diastolic blood pressure, usually due to anti-hypertension medication, should be recommended to prevent the development of severe foot ulcer. KEYWORDS: diabetic foot ulcers, severity, glycemic control, hypertension, poor circulation, neuropathy
Reconstruction of A Huge Soft Tissue Deffect in Flank Region Using Rectus Femoris Flap Meirizal Hasan; Rahadyan Magetsari; Rezky Saraswaty
Journal of Global Pharma Technology Volume 13 Issue 04 (2021) April 2021
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Introduction:Coverage of full-thickness large flank defect is a challenging procedure for surgeons. The rectus femoris (RF) muscle flap is an excellent donor muscle for many reconstructions. The vascularized rectus femoris (RF) muscle flap has been proved to be effective to cover infected vascular grafts in the flank region. Outcome of the treatment can be evaluated by evaluating the patient daily activity. Case Report:This was a case report conducted on patient with huge soft tissue deffect in flank region. A 62 years old male with large defect of the right flank region due to infection of the abdominal cavity after appendectomy 2 months ago. The wound size 15 x 7 x 7 cm, with the base is bowel, with serohemoragic discharge. Then perform debridement and rectus femoris flap. A month after operation, the patient came to the Sardjito General Hospital with defect of the right hypogastric region and then VAC was performing in this patient. Two month after VAC, the wound was covered by granulating tissue and then the patient underwent FTSG. A month after the second operation, the patient came to outpatient clinic, able to walk, with the condition of the wound was good, no visible sign of infection. Conclusion:From this case report shows that rectus femoris flap has a good result to coverage the huge soft tissue defect in flank region. The patient can perform a simple daily living. Keywords: Rectus femoris, Flank defect, Flap.
Donor Site Morbidity after Anterior Iliac Bone Graft Harvesting Rahadyan Magetsari
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
Publisher : Journal of Global Pharma Technology

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Bone substitutes are being increasingly used especially in oncologic surgery, traumatology, revision prosthetic surgery and spine surgery. Bone substitute can be defined as a synthetic, inorganic or biologically organic combination which can be inserted for the treatment of a bone defect instead of autogenous or allogenous bone. Despite the improvement of research, human bone grafts persist to be the most effective bone substitutes to replace bone loss. This research was retrospective study conducted in consecutive sampling in Sardjito General Hospital Yogyakarta from January 2014 to Desember 2018. Patients underwent anterior iliac crest bone graft harvesting was included. 4 months after the procedure, the donor site morbidity was identified. The parameters used in this study are pain score using visual analog scale, paresthesia, problem in walking, wound infection, scar satisfaction and major morbidity. Anterior iliac bone graft harvesting resulted in minimal morbidity and neither pain or functional limitations. It also provides the optimal bone graft material, yields minimal morbidity, and is an acceptable choice in autologous bone graft harvesting.
Co-Authors Aditya Fuad Robby Aditya Fuad Robby Triangga Astri Ferdiana Bernadeta Fuad Paramita Rahayu Dananjaya Putramega Dimas Triaryo Ery Kus Dwianingsih Fikar Arsyad Hakim Galih Prasetya Sakadewa Handoko Handoko Hengkie Marseno Hilmi Muhammad Irianiwati Widodo Luthfi Hidayat Meirizal Hasan Muhamad Afrizal Farkhan Prisilla Desfiandi Punto Dewo Rezky Saraswaty Rini Dharmastiti Sakti, Yudha Mathan Suyitno Suyitno Triangga, Aditya Fuad Robby Yossie Atyandhari Yuliaji Narendra Putra Yuni Artha Prabowo Putro Zikrina Lanodiyu