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Comparative Analysis of Post Rubber Band Ligation and Stapled Hemorrhoidopexy Complications of Grade 2 and 3 Internal Hemorrhoids Mazni, Yarman; Basir, Ibrahim; Sumanto, Sumanto; Budiningsih, Setyawati
The New Ropanasuri Journal of Surgery
Publisher : UI Scholars Hub

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Abstract

Introduction. The management of second–and third–degree internal hemorrhoid consists of non–surgical and surgical treatments. If non–surgical treatment does not succeed, then the recommended therapy is minimal invasive or surgery, depends on the clinical condition. Along with the development of science and technology, a technique known as rubber band ligation (RBL) and stapled hemorrhoidopexy emerges. In Indonesia, there is no data that can describe the distribution of postoperative complication rate. Method. A comparative cross–sectional study was conducted by gathering short term outcomes data from the subjects' medical records that underwent RBL or SH between 2011 to 2014 in three different hospitals in Jakarta. A univariate analysis was conducted to assess postoperative complications of RBL and SH subjects of second–and third–degree internal hemorrhoids. We use chi square test to assess the factors that influence the complications of categorical variables, and Fisher test if the chi square condition is not met. Results. Among 183 subjects, 49.2% underwent RBL and 50.8% SH. Second degree internal hemorrhoids were 40% and third degree were 60%. Postoperative complications consist of pain (RBL 4.4%, SH 8.8%), hemorrhage (RBL 2.3%, SH 4.9%), urinary retention (RBL 0, SH 2.7%), infection (RBL 0.5%, SH 1.6%) and stenosis (RBL 0, SH 0.5%). Postoperative complications on second degree internal hemorrhoidal was 8.2% and third degree 13.1% (p = 0.71). Complication of subject with third degree internal hemorrhoids after RBL 2.8%, SH 19.4% (p = 0.03). Conclusion. Complications of second– and third–degree internal hemorrhoids post RBL are no different with SH while for third degree internal hemorrhoid, complications after RBL ware significantly lower than SH.
Validasi Kuesioner EORTC QLQ-CR29 untuk Menilai Kualitas Hidup Pasien Kanker Kolorektal di Indonesia Pramaningasih, Maelissa; Basir, Ibrahim; Jeo, Wifanto Saditya; Kekalih, Aria
Jurnal llmu Bedah Indonesia Vol 47 No 1 (2019): Artikel Penelitian
Publisher : Ikatan Ahli Bedah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46800/jibi-ikabi.v47i1.19

Abstract

Latar Belakang: Saat ini di Indonesia tidak ada kuesioner standar untuk menilai kualitas hidup pasien dengan kanker kolorektal. European Organization for Research and Treatment of Cancer Quality of Life Questionnaire ColoRectal 29 (EORTC QLQ-CR29), adalah sebuah kuesioner yang terstandarisasi untuk menilai kualitas hidup yang umum digunakan pada negara maju. Penelitian ini mencoba membuktikan bahwa EORTC QLQ-CR29 adalah kuesioner yang valid dan reliabel untuk digunakan di Indonesia. Metode: Kuesioner EORTC QLQ-CR29 diterjemahkan kedalam bahasa Indonesia, dan diterjemahkan kembali ke bahasa Inggris. Dilakukan sebuah studi pilot terlebih dahulu, kemudian studi utama ke pasien kanker kolorektal pada poliklinik Bedah Digestif di RSUPN dr.Cipto Mangunkusumo. Desain studi cross-sectional, digunakan intraclass correlation coeficient (ICC) untuk menilai test-retest realiability. Konsistensi internal dievaluasi menggunakan Cronbach’s α coefficient. Validitas konvergen dan diskriminan dianalisa dengan multi-trait scaling. Validitas klinis dievaluasi berdasarkan perbedaan klinis yang telah diketahui sebelumnya menggunakan known-group comparisons. Hasil: Sebanyak lima puluh dua pasien yang berpartisipasi pada penelitian ini. Proses penterjemahan membutuhkan sedikit perubahan akibat adanya perbedaan budaya. Uji test-retest dilakukan pada 17 subjek, yang menunjukkan nilai yang dapat diterima (0.67-1.00). Nilai Cronbach’s α coefficient 0,77-0,86, nilai ini melebihi kriteria 0,7. Pada multi-trait scaling analysis menunjukkan skala multi-item memenuhi standar validitas konvergen dan diskriminan. Pada uji known group comparison menunjukkan kualitas hidup yang berbeda berdasarkan lokasi tumor. Simpulan: Dibutuhkan adaptasi budaya dalam proses penterjemahan. Kuesioner EORTC QLQ-CR29 yang telah diterjemakan merupakan kuesioner yang valid dan reliabel untuk menilai kualitas hidup pasien kanker kolorektal di Indonesia.
Validasi Kuesioner EORTC QLQ-CR29 untuk Menilai Kualitas Hidup Pasien Kanker Kolorektal di Indonesia Maelissa Pramaningasih; Ibrahim Basir; Wifanto Saditya Jeo; Aria Kekalih
Jurnal llmu Bedah Indonesia Vol. 47 No. 1 (2019): Maret 2019
Publisher : Ikatan Ahli Bedah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46800/jibi-ikabi.v47i1.19

Abstract

Latar Belakang: Saat ini di Indonesia tidak ada kuesioner standar untuk menilai kualitas hidup pasien dengan kanker kolorektal. European Organization for Research and Treatment of Cancer Quality of Life Questionnaire ColoRectal 29 (EORTC QLQ-CR29), adalah sebuah kuesioner yang terstandarisasi untuk menilai kualitas hidup yang umum digunakan pada negara maju. Penelitian ini mencoba membuktikan bahwa EORTC QLQ-CR29 adalah kuesioner yang valid dan reliabel untuk digunakan di Indonesia. Metode: Kuesioner EORTC QLQ-CR29 diterjemahkan kedalam bahasa Indonesia, dan diterjemahkan kembali ke bahasa Inggris. Dilakukan sebuah studi pilot terlebih dahulu, kemudian studi utama ke pasien kanker kolorektal pada poliklinik Bedah Digestif di RSUPN dr.Cipto Mangunkusumo. Desain studi cross-sectional, digunakan intraclass correlation coeficient (ICC) untuk menilai test-retest realiability. Konsistensi internal dievaluasi menggunakan Cronbach’s ? coefficient. Validitas konvergen dan diskriminan dianalisa dengan multi-trait scaling. Validitas klinis dievaluasi berdasarkan perbedaan klinis yang telah diketahui sebelumnya menggunakan known-group comparisons. Hasil: Sebanyak lima puluh dua pasien yang berpartisipasi pada penelitian ini. Proses penterjemahan membutuhkan sedikit perubahan akibat adanya perbedaan budaya. Uji test-retest dilakukan pada 17 subjek, yang menunjukkan nilai yang dapat diterima (0.67-1.00). Nilai Cronbach’s ? coefficient 0,77-0,86, nilai ini melebihi kriteria 0,7. Pada multi-trait scaling analysis menunjukkan skala multi-item memenuhi standar validitas konvergen dan diskriminan. Pada uji known group comparison menunjukkan kualitas hidup yang berbeda berdasarkan lokasi tumor. Simpulan: Dibutuhkan adaptasi budaya dalam proses penterjemahan. Kuesioner EORTC QLQ-CR29 yang telah diterjemakan merupakan kuesioner yang valid dan reliabel untuk menilai kualitas hidup pasien kanker kolorektal di Indonesia.
Management of Sigmoid Cancer In dr Cipto Mangunkusumo Hospital during 2008–2011 Wahyu Sriningsih; Ibrahim Basir; Benny Philippi
Jurnal llmu Bedah Indonesia Vol. 43 No. 1 (2014): September 2014
Publisher : Ikatan Ahli Bedah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46800/jibi-ikabi.v43i1.67

Abstract

A retrospective analysis was performed to sigmoid cancer cases in the digestive surgery division of Cipto Mangunkusumo Hospital during the period of 2008–2011. Fifty–two cases were analyzed for metastases, stages and histopathology; mortality and morbidity were calculated for anastomotic leakage, 3–year survival, and incidence of local recurrence. Three–year survival analysis was performed using Kaplan–Meier based on staging and histopathology. The overall operative mortality was 1.9%, and the anastomotic leakage incidence was 8.1%. The incidence of local recurrence was 9.1%. The 3–year survival rates based on Dukes Staging were as follows: 100% survival for Dukes A, 95.5% for Dukes B and 61.1% for Dukes C and 0% for Dukes C. The 3–year survival rates in sigmoid cancer according to histopathology were 73.5% for well differentiated, 63.6% for moderately differentiated and 100% for poorly differentiated (sample size was one patient, could not be assessed), with 50% survival for mucinous histopathology. The overall survival in this sigmoid cancer study was 69.2%.
Chemotherapy for Advanced Colorectal Cancer among Indonesians in a Private Hospital in Jakarta: Survival when Best Treatment is Given Aru W Sudoyo; Ibrahim Basir; Levina Pakasi; Maureen Lukman
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 14, NUMBER 1, April 2013
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (366.075 KB) | DOI: 10.24871/14120133-8

Abstract

Background: Survival of colorectal cancer in Indonesia is thought to be shorter due to to several factors, among these: ethnic, nutritional, and the low affordability factors. Aim of this study to assess and evaluate survival in advanced colorectal cancer when given the best drugs available as recommended by international guidelines.Method: A historical cohort study was done in patients with advanced colon or rectal cancer between 2008 and 2010 at Medistra Hospital. Cases were retrieved from medical record data. Subjects were included if they were diagnosed or had a relapse of their disease during the study period and were followed until they died or lost to follow-up. Staging procedure was done using the tumor node metastasis (TNM) system. All patients received the combination of 5-uorouracil (5-FU)/leucovorin (LV), oxaliplatin for 6 cycles (FOLFOX4) as the standard  rst-line regimen for metastatic colorectal cancer (mCRC) in Indonesia. Oral capecitabine and targeted therapy such as bevacizumab and cetuximab might were also given, whenever indicated.Results: Nineteen patients (48.7%) died during the study period, while the rest were alive or lost to follow-up. The median overall survival of patients was 18 months (95% CI = 6.98 – 29.02 months). The longest survival was76 months (the patient is still alive when this manuscript was being prepared). Patients with colon cancer tended to live longer than rectal cancer, i.e. 21 vs. 15 months; log-rank p = 0.147. There was no signi cant difference of survival between patients with stage IV disease and relapse cases, i.e. 18 vs. 12 months, log-rank p = 0.807. Conclusion: With proper treatment and access to cytostatics and biologicals, advanced colorectal cancer among Indonesian patients have the same survival rates as patients in more developed countries as reported in the literature. Keywords: advanced colorectal cancer, chemotherapy, survival