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All Journal Indian Journal of Forensic Medicine & Toxicology
Sujay Thakkar
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Comparative Study of Magnesium Sulphate added to Bupivacaine and Ropivacaine Local Infiltration of Wound for Postoperative Analgesia in Patients Undergoing Upper Abdominal Surgery: A Randomized Double Blind Study Anuja Agrawal; Sujay Thakkar; Akhilesh Chhaya; Malini Mehta
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14277

Abstract

Aim: To compare subcutaneous infiltration of Inj Bupivacaine with inj MgSO4and Inj Ropivacaine withInjMgSO4 for postoperative analgesia undergoing upper abdominal surgery. Goal: To determine duration ofanalgesia, doses of rescue analgesia, VAS at different time intervals.Background: Post-operative pain is most neglected entity. We should use availableresources inoptimummanner for improving pain managementstrategies.Methods: A Prospective, double-blinded, randomized studyof 50 patients undergoing upper abdominalsurgery divided into group B and R. Infiltration was done in the subcutaneous plane by surgeon before skinclosure. Group B: Inj. Bupivacaine 50mg (10ml of 0.5% Inj . Bupivacaine) with Inj.MgSO4 500mg (1ml ofInj 50% MgSO4) diluted with NS 9 ml to make total volume of 20 ml whereas, Group R: Inj Ropivacaine50 mg (6.7 ml of 0.75% Inj. Ropivacaine) with Inj MgSO4 500 mg diluted with NS (12.3 ml) making a totalvolume of 20 ml. In postoperative period, parameters noted were vitals and Visual Analogue Score (VAS)for 24 hours.Results: In group R, moderate pain was seen in 40%of the patients at T12 whereas in group B 48% hadmoderate pain. Total no. of rescue analgesic doses required in Group R is 2.1 +/- 0.5 and in Group B is 2.6+/- 0.5 in 24 hrs and has significant differencestatistically.Conclusion: Group R had better VAS scores at T24 and reduced no.of rescue analgesic doses.
An Observational Study of Intravenous Granisetron Vs Oral Gabapentin in Preventing Postoperative Nausea and Vomiting after Middle Ear Surgery Malini Mehta; Akshata Thakurdesai; Sujay Thakkar
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15334

Abstract

Background- Postoperative nausea and vomiting (PONV) is one of the most unpleasant complications after middle ear surgery. Several studies have demonstrated use of gabapentin as antiemetic. This study aims at comparison of intravenous granisetron vs oral gabapentin in preventing PONV. Methods - 64 patients of ASA I or II between the ages of 18 and 65 years were divided equally into two groups. Patients in group I received 3mg granisetron iv 2 minutes and patients in group II received 300 mg gabapentin orally 1 hour prior to surgery. Patients were premedicated with inj. glycopyrrolate and inj. midazolam. Anaesthesia was induced, maintained and reversed in usual manner. Haemodynamic changes and number of episodes of nausea and vomiting were recorded upto 24 hours postoperatively. No statistically significant difference was observed in both the groups at 0 and 1 hour in preventing PONV (p<0.05). Next 24 hours postoperatively neither group showed PONV. No significant haemodynamic changes were observed and there were noside effects in either of the groups.Conclusion- There was no statistically significant difference in prevention of PONV in the patients who had either received inj granisetron 3mg i.v. 2 minutes prior to surgery or oral Gabapentin 300mg 1hour prior to surgery after middle ear surgery without any side effects.
A Comparitive Study Between Magnesium Sulphate Versus Dexamethasone as an Adjuvant to Bupivacaine in Supraclavicular Brachial Plexus Block Sara Mary Thomas; A. Anjali; Jayshri B. Desai; Sujay Thakkar
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15937

Abstract

Introduction: Magnesium Sulphate and Dexamethasone are used as adjuvants to local anaesthetics inregional anaesthesia to improve the quality of blockObjective: To compare the efficacy of magnesium sulphate and dexamethasone on the characteristics of theblock and its effect on postoperative analgesia when added as an additive to bupivacaine in supraclavicularbrachial plexus block.Materials and Methods: Fifty patients belonging to American Society of Anaesthesiologists (ASA) GradeI and II, aged between 18 to 55 years, scheduled for elective upper limb surgeries under supraclavicularbrachial plexus block were enrolled in this study. Patients were equally divided into two groups : group Mreceived 0.5% Bupivacaine 30ml with 10% Magnesium sulphate 5 ml (500mg) and group D received 0.5%Bupivacaine 30ml with Dexamethasone 2ml (8mg) + Normal saline 3ml. Onset and duration of sensory andmotor block , duration of postoperative analgesia and any complications were observed.Results: In our study the demographic profile of patients, duration of surgery and ASA status between thetwo groups were comparable. Onset of sensory block was earlier in group D than group M (17.12±0.93minutes and 19.40 ±1.08 minutes respectively, p=0.001). Duration of motor block and analgesia were longerin group D as compared to group M (479.00 ±50.83 minutes vs 346.40 ±32.77 minutes respectively, p=0.001 for motor block and 533.80 ±59.80 minutes vs 415.00 ±57.23 minutes respectively, p=0.001 foranalgesia). No significant side effects were noted.Conclusion: Dexamethasone is a better adjuvant than Magnesium Sulphate when added to bupivacaine insupraclavicular brachial plexus block as it prolongs duration of motor block and analgesia significantly withminimal side effects.
Co-Authors A. Anjali Akhilesh Chhaya Akshata Thakurdesai Anuja Agrawal Jayshri B. Desai Malini Mehta Sara Mary Thomas