Article Per Year (5 Year)
p-Index From 2020 - 2025
0.444
P-Index
This Author published in this journals
All Journal Indian Journal of Forensic Medicine & Toxicology
Phatcharin Mahawong
Unknown Affiliation
Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Haplotype Profiling of Y-STRs among Northern Population in Thailand Supakit Khacha-ananda; Phatcharin Mahawong; Thida Kaewkod
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14450

Abstract

Background: The investigation of Y-short tandem repeats (Y-STRs) has been widely performed in forensiccaseworks. Due to variation between populations, understanding of genetic information within individual apopulation could provide the database and scientifically reliable results. This study was to investigate alleleand haplotype frequencies of Y-STRs among localized people who lived in northern Thailand.Methods: A retrospective descriptive study was conducted by gathering medical reports of Y-STRs typing.The allele frequency and gene diversity as well as haplotype frequency and diversity were calculated.Pairwise genetic distance (Rst) was also calculated based on haplotype pattern by using AMOVA andMultidimensional Scaling (MDS) tools.Results: The result showed that DYS389II, DYS439, and DYS392 represented the highest number of allelepatterns. The highest and lowest allele frequency was found to be allele 14 of DYS437 and allele 13 ofDYS437, respectively. The highest and lowest gene diversity was observed in DYS389II and DYS437,respectively. One-hundred and sixty different haplotypes were defined where 144 carried a unique haplotypeand 16 carried a replicate haplotype. A significant Rst value was obtained between the studied population andcentral Thai population.Conclusion: This study provided genetic database of Y-STRs among localized population in northern regionof Thailand. The genetic structure of our subjects also represented the significant close relationship withsome other populations in Southeast Asia.
Allele Frequencies and Forensic Statistical Parameters for 21 Autosomal Short Tandem Repeats (STRs) loci in Northern Thai Population Supakit Khacha-ananda; Yutti Amornlertwatana; Phatcharin Mahawong; Nitaya Khamkomkai
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 3 (2022): Indian Journal of Forensic Medicine and Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i3.18310

Abstract

Background: Although the genetic information of STRs has been established over the entire world, the differentcharacteristics between populations influenced the STRs information. FBI’s guideline recommended to expandadditional number of STRs loci to increase power of discrimination and exclusion. Unfortunately, the currentdata of STRs in northern Thai population have not fully covered additional loci. The aim of this study is to obtainaccurate allele frequencies of STRs among northern Thai population.Methods: The genetic profiles ofunrelated individuals were characterized by Investigator 24 plex Go kit. Allelefrequencies and forensic statistical parameters were calculated within GenoProof®3and Arlequin ver 3.5.2.2.Results: The SE33 and TH01 loci represented largest and lowest number of different alleles, respectively. Therewas no significant deviation from the Hardy–Weinberg equilibrium (HWE) after Bonferroni correction in all loci(p=0.002). The SE33 locus showed the greatest PD and PE, whereas the TPOX represented the lowest PD and PE.The studied population (northern Thai) appear to be most closely related to previously reported populationscontaining of Chinese, Japanese, and Vietnamese based on allele frequency.Conclusion: Our results recommended that current autosomal STRs data extended the application of STRs typingin parentage analyses and human identification among the localized population in northern region of Thailanddue to highly informative polymorphic data.
Co-Authors Nitaya Khamkomkai Supakit Khacha-Ananda Thida Kaewkod Yutti Amornlertwatana