<![CDATA[Background: The investigation of Y-short tandem repeats (Y-STRs) has been widely performed in forensiccaseworks. Due to variation between populations, understanding of genetic information within individual apopulation could provide the database and scientifically reliable results. This study was to investigate alleleand haplotype frequencies of Y-STRs among localized people who lived in northern Thailand.Methods: A retrospective descriptive study was conducted by gathering medical reports of Y-STRs typing.The allele frequency and gene diversity as well as haplotype frequency and diversity were calculated.Pairwise genetic distance (Rst) was also calculated based on haplotype pattern by using AMOVA andMultidimensional Scaling (MDS) tools.Results: The result showed that DYS389II, DYS439, and DYS392 represented the highest number of allelepatterns. The highest and lowest allele frequency was found to be allele 14 of DYS437 and allele 13 ofDYS437, respectively. The highest and lowest gene diversity was observed in DYS389II and DYS437,respectively. One-hundred and sixty different haplotypes were defined where 144 carried a unique haplotypeand 16 carried a replicate haplotype. A significant Rst value was obtained between the studied population andcentral Thai population.Conclusion: This study provided genetic database of Y-STRs among localized population in northern regionof Thailand. The genetic structure of our subjects also represented the significant close relationship withsome other populations in Southeast Asia.]]>
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