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All Journal Jurnal Penelitian Kesehatan Suara Forikes Window of Health : Jurnal Kesehatan Indian Journal of Forensic Medicine & Toxicology
Setyo Trisnadi
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Health Professions Medicine & Pharmacology Nursing Public Health

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Reconstruction of Prevention and Handling of Stunting Policy in Public Health Center Retno Widhiastuti; Mahmutarom HR; Setyo Trisnadi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14874

Abstract

Introduction: Indonesia has severe nutritional problems, one of which is stunting. Stunting is a chronicmalnutrition condition caused by many multi-dimensional. According to the Minister of Health Republicof Indonesia No. 43 of 2019 about Public Health Center, Public Health Center Services are part of publicservices and are basic routine health services consisting of Public Health Efforts (UKM) and IndividualHealth Efforts (UKP), one of which is the prevention and handling of stunting in Public Health Center.Demak III Public Health Center is a health center in the city that has an area of 18.78 km with a populationof 38,218 people precisely on the road Cempaka Raya No. 5 Katonsari, Demak consists of 5 villages and1 village namely Kalikondang village, Katonsari, Donorojo, Mangunjiwan, Cabean, and Tempuran. Of thesix villages, Donorejo village is the village that has the highest number of stunting cases compared to othervillages.Research Objectives: The purpose of this study is to find out and analyze the reconstruction of preventionand handling of stunting policy in Public Health Center.Research Methods: This research uses the paradigm of constructivism, which is the policies that exist ingovernment agencies can be examined objectively related to accurate data, then constructed through theconcept of law that is only tested again its strength. Methods used with Critical thinking. Critical thinkingis the ability to think clearly and rationally, understand the logical relationship between ideas. The samplingmethod is a non-random sampling technique that is purposive sampling is a way of taking subjects based ona specific goal.Results and Discussion: The description of the reconstruction of prevention and handling of stunting policyin Public Health Center through integration actions with stakeholders of government agencies in the DemakRegency area is still partial. With the policy that is still partial, in the prevention and handling of stunting bycriticizing (critical thinking) existing policies. Prevention and reduction of stunting is carried out by healthworkers through programs with cross-sectors and networks already running.
Pengaruh Penambahan Citronella pada Formalin terhadap Efektivitas Embalming Otot Gastrocnemius Setyo Trisnadi
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 12 (2021): Nomor Khusus November 2021
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/%x

Abstract

Latar belakang : Penggunaan formalin memiliki efek samping yang berpotensi membahayakan kesehatan serta bau yang ditimbulkan sangat mengganggu lingkungan sekitar. Citronella merupakan salah satu minyak wangi alami yang memiliki sifat antibakteri. Tujuan penelitian ini yaitu mengetahui pengaruh penambahan citronella pada formalin terhadap efektivitas embalming otot gastrocnemius tikus galur Wistar jantan. Metode : Penelitian eksperimental dengan rancangan post test only control group design dengan 25 ekor tikus galur wistar jantan dibagi dalam 5 kelompok kemudian didislokasi servikal. Kelompok I disuntikan 10 ml formalin. Kelompok II-V disuntikan campuran formalin-citronella dengan dosis bertingkat. Setiap kelompok diambil jaringan otot gastrocnemius 48 jam post mortem kemudian diamati secara histopatologi dengan mikroskop cahaya dengan pengecatan HE dengan perbesaran 400x. Data dianalisis dengan uji normalitas dan homogenitas kemudian dilanjutkan dengan uji Kruskal Wallis dan Mann Whitney. Penelitian ini telah melewati ethical clearance. Hasil : Gambaran histopatologi otot gastrocnemius tikus galur wistar jantan yang diberi formalin 48 jam post mortem adalah 1,88±3,67% sedangkan pada campuran formalin-citronella 2,5 ml adalah 18,11±10,01%, pada campuran formalin-citronella 5 ml adalah 4,82± 3,45%, pada campuran formalin-citronella 7,5 ml adalah 17,54±10,71% dan pada campuran formalin-citronella 10 ml adalah 26,92±22,72%. Hasil uji Kruskal Wallis menunjukkan hasil yang signifikan p=0,009 (p
The Influence of Blue Butterfly Pea Flower (Clitoria Ternatea) Gel Extract on Interleukin-10 (IL-10) and Glutathione Peroxidase (GPx) Levels Siti Asichah; Titiek Sumarawati; Setyo Trisnadi
Window of Health : Jurnal Kesehatan Vol 7 No 3 (July 2024)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/woh.v7i2.1418

Abstract

Long-term exposure to Ultraviolet B (UV-B) radiation causes increased skin darkening owing to a reaction to oxidative stress leading to elevated levels of nitric oxide (NO) and reactive oxygen species (ROS). Excessive ROS induces signal transduction and stimulates the transcription factor NF-kβ, an inflammatory mediator. Butterfly flower extract has high antioxidant levels, inhibiting ROS production and reducing inflammatory conditions, hindering MMP, preventing fibroblast cell apoptosis, and inhibiting collagen degradation. However, the role of butterfly pea flowers on IL-10 and GPx gene levels in melasma skin due to UV-B exposure is unclear. This research aims to assess the effectiveness of applying Blue Butterfly Pea Flower Extract Gel on the level of the IL-10 and GPx genes in Wistar rat strains exposed to UV-B. The UV-B-experimental research with the post-test control group. Groups K2, K3, and K4 were each exposed to UV-B at 302 nm with a MED of 160 mJ/cm2, while group K1 was the healthy group. K3 was given 5% butterfly pea flower gel, K4 was given 10% gel daily for 14 days, and K2 received base gel. On the 21st day, ELISA examined the tissue for IL-10 and GPx levels. The IL-10 gene level in the treatment group increased with higher dosages (K3=83.27±3.11, K4=90.66±4.00) compared to controls (K2=33.26±2.98, K1=104.7±3.26). The relative level of the GPx gene in the treatment group increased along with increasing dose (K3=44.90±1.44, K4=54.09±1.00) compared to the control group (K2=29.54±0.85, K1=62.43±0.85). Administration of butterfly pea flower gel can increase the level of the IL-10 gene and the level of the GPx gene in the skin tissue of mouse models of UV-B light-induced hyperpigmentation.
Co-Authors Mahmutarom HR Retno Widhiastuti Siti Asichah Titiek Sumarawati