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All Journal Jurnal Ilmu Pertanian Indonesia Jurnal Penelitian Sains Jurnal Ilmiah Multidisiplin Indonesia Journal of Natural Product for Degenerative Diseases
Ros Sumarny
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Earth & Planetary Sciences Engineering Health Professions Mathematics Medicine & Pharmacology Physics Public Health

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Pengobatan penyakit tumor mammae melalaui operasi (matektomi dan ovariohisterektomi) dan kombinasinya (tanaman herbal) pada hewan Gunanati Soedjono; Bambang Pontjo Priosoeryanto; Ietje Wientarsih; Ros Sumarny
Jurnal Ilmu Pertanian Indonesia Vol. 14 No. 1 (2009): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1495.219 KB)

Abstract

Tumor or neuplasm can be meant as a abnormal and uncontrol growth of the transformation tissue or the change of one or main location of the body. This degenerative desease is one of the deseases in the animal pet especially dog and cat. Generaly this tumor deseases can be used with therapy using surgery and usually will relapse after six months. from our previous research had succeded to examp by using activity in vitro antiproliverati from extract plant (nusa indah, blustru and temu putih) combined with recombinanct interferon dog ( rCaiFN). The above phenomenon indicate a new hope to make a therapy for tumor desease, especially for dog and cat and may be in the future can be used for human. In this research we used 21 female rabbits and divided into 7 treatment groups, consisted of 3 rabits ie : group A. negative control; B. surgery, preventive and curative curcumine; C. positive control; D. positive control and surgery; E. surgery and preventive zedoaria capsul; F. surgery , preventive and curative zedoaria capsule and G. surgery and curative zedoaria capsule . Induction with carcinogen (MNU) treated every weeks during 3 weeks. Surgery is executed in the 5 weeks and giving capsule zedoaria is executed every day for 4 weeks (preventive or curative) and 8 weeks (preventive andcurative). Result of the research indicated that mammae tumor has been made successfully by MNU (n-metil-nnitrosuria) induction to rabit and capsule zedoaria and it has been treated by doing surgery therapy (mastectomy and ovariohisterectomy). Also decombination of zedoaria capsule. The result of the research indicated lindrance of tumorgenesis to the group which is given by zedoaria capsule. from the clinical picture shows that zedoaria capsule does not give negative effect to clinical picture (temperature, respiratory frequency and heart rate)/ still normal to all the groups. Tumor induction with (MNO) at mammary gland will occur allegic reaction inflammatory which is the beginning of tumor mechanism which is marked by total leucosit, neutrofil, eosinofil, and basofil increase. Tumor therapy with surgery (masektomi and ovariohisterektomi) and the combination with rimpang Temu Putih capsule can decrease the number of leucosit, neutrofil and limfosit but only a little affectmonosit number, although statistically it does not show real difference.
Kajian Pola Penggunaan Antibiotik Profilaksis Hubungannya Dengan Angka Kejadian Infeksi Daerah Operasi (IDO) Pada Pasien Bedah Digestif Di Rumah Sakit Swasta Kiki Amelia; Ros Sumarny; Delina Hasan; Hafidh Komar
Jurnal Penelitian Sains Vol 21, No 1 (2019)
Publisher : Faculty of Mathtmatics and Natural Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (138.792 KB) | DOI: 10.56064/jps.v21i1.527

Abstract

Abstract: Prophylaxis antibiotics are given to prevent surgical site infection (SSI). This study aimed to examine the pattern of the use of prophylaxis antibiotics on the incidence and SSI risk factors. This study was an observational analytic study with a cross sectional design. SSI observation was directly observed in postoperative wounds, the first in the treatment room at the time of dressing change, the second observation was carried out in the surgical clinic at the time of repeated control. The total sample during the study period was 57. The results of this study showed the incidence of SSI in digestive surgery patients was 17.5% (10 out of 57 samples). The most widely used prophylaxis antibiotics ware the third generation cephalosporin group ceftriaxone (96,5%)
Analysis of Potentially Inappropriate Medication (PIM) Risk Factors In Geriatric Hypertension Patients With Comorbids In Inpatients Based On Beer's® 2023 Criteria Hospital X Fitria Aptika; Ros Sumarny; Hesty Utami R; Mida P
Jurnal Ilmiah Multidisiplin Indonesia (JIM-ID) Vol. 4 No. 05 (2025): Jurnal Ilmiah Multidisplin Indonesia (JIM-ID), June 2025
Publisher : Sean Institute

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Abstract

Hypertension is still a health problem for the elderly. Polypharmacy, which is common in the elderly and cannot always be avoided, often poses a risk of poor outcomes and can increase the risk of Potentially Inappropriate Medication (PIM). The purpose of this study was to identify socio-demographic characteristics, use of drugs that meet the Beer's® 2023 criteria, the relationship between the number of drugs prescribed and the incidence of PIM, the relationship between the length of hospitalization and the incidence of PIM and what risk factors influence the incidence of PIM in geriatric patients with hypertension with comorbidities in hospitalization at Hospital X. The research method used a cross-sectional design with prospective data collection. The results showed that geriatric patients were more in the 65-69 year group by 55%, the most dominant gender was male by 38%, where all patients had various comorbidities which meant receiving ≥ 10 drugs with a maximum length of hospitalization ≥ 5 days. The relationship between the number of drugs and the incidence of PIM has a significant relationship with a value of (p<0.25) 0.197, which means that the number of drugs and the incidence of PIM has a significant correlation. The relationship between the length of hospitalization and the incidence of PIM has a significant relationship with a value of (p<0.25) 0.169, which means that the length of treatment affects the incidence of PIM. Risk factors that trigger the incidence of PIM are gender, number of drugs and length of hospitalization.
Study of The In Vivo Anti-Inflammatory, Antipyretic and Analgesic Effect of The Ethanol Extract Indian Nettle Plant (Acalypha indica Linn) Khairani, Sondang; Ros Sumarny; Yurista Elystra
Journal of Natural Product for Degenerative Diseases Vol. 1 No. 2 (2024): JNPDD March
Publisher : Faculty of Pharmacy Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58511/jnpdd.v1i2.6506

Abstract

The body can experience fever and pain, when inflammation occurs. Indian nettle plant (Acalypha Indica Linn.) are known to contain flavonoid compounds which are thought to have anti-inflammatory, antipyretic, and analgesic effect. This study aims to test the anti-inflammatory, antipyretic, and analgesic effect of the ethanol extract of 70% Indian Nettle plant. Method each test used 5 groups, negative control all given Na CMC 0,5%. Antiinflammatory use rats with Winter method, aspirin 40,43mg/200gBB, the test group dose 70mg/200gBW (I), 140mg/200gBW (II), 280mg/200gBW (III), antipyretics use rats with Brewer's yeast method, aspirin 21,45mg/200gBW, the test group dose 70mg/200gBW (I), 140mg/200gBW (II), 280mg/200gBW (III). Analgesic use mice with the Siegmund method, aspirin 3,10mg/20gBB, the test group dose of 10mg/20gBB (I); 20mg/20gBB (II); 40mg/20g BW (III). Results Kruskall Wallis test, the anti-inflammatory effect significant difference to negative control, p value <0,05. Percentage of inhibition positive control edema and test dosage I, II, and III obtained 34,44%; 18,88%; 21,37%, and 29,61%. The Mann Whitney test, the antipretic and analgesic effects significant difference to the negative control, p value <0,05. The decreased percentage of fever in positive control and dosage I, II, and III test preparations was 3,74%; 2,60%; 2,55%; 3,01%. Inhibition percentage of stretching positive control and test dosage I, II, and III obtained 41,05%; 24,46%; 27,78%; and 33,31%. Conclussion: Wriggling inhibition (analgesic) had the highest presentation dose III 33,31% compare to anti-inflammatory and antipyretic activities, lower than aspirin as positive control 41,05% (p<0,05).
Co-Authors Bambang Pontjo Priosoeryanto Delina Hasan Fitria Aptika Gunanati Soedjono Hafidh Komar Hesty Utami R IETJE WIENTARSIH Kiki Amelia Mida P S.Farm., M.Farm., Apt, Sondang Khairani Yurista Elystra