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All Journal Ilomata International Journal of Tax and Accounting Biomedika Poltekita: Jurnal Ilmu Kesehatan
Burhannudin
Jurusan Analis Kesehatan, Poltekkes Denpasar, Denpasar
Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Social Sciences

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Empirical Evidence from the Indonesia Stock Exchange: The Influence of Debt to Equity Ratio (DER) and Return on Equity (ROE) on Sharia Stock Prices Sri Bulkia; Burhannudin; Kurniaty Kurniaty; Alpia Rahmah; Mustaghfiri Abdan
Ilomata International Journal of Tax and Accounting Vol. 3 No. 3 (2022): July 2022
Publisher : Yayasan Ilomata

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (385.567 KB) | DOI: 10.52728/ijtc.v3i3.500

Abstract

This paper aims to obtain empirical evidence about the influence of the Debt to Equity Ratio (DER) and Return on Equity (ROE) on Islamic stock prices, either partially or simultaneously. An exploratory investigation of 26 companies classified as sharia with the criteria of the Jakarta Islamic Index on the Indonesia Stock Exchange. The secondary data analysis used is to collect complete financial data for the 2014-2018 period. The secondary data was successfully examined as many as 130, then processed using SPSS 26, then analyzed using regression. The findings of the investigation provide empirical evidence that the Debt to Equity Ratio (DER) and Return on Equity (ROE) have a positive and significant influence on Islamic stock prices, either partially or simultaneously. This study provides a theoretical contribution to limited research exploring the Debt to Equity Ratio (DER) and Return on Equity (ROE) with Islamic stock prices on the stock exchange in Indonesia. In practice, this research provides significant insights that can be used to measure the company's health and assess the company's ability to generate returns from shareholder investments of companies classified as sharia.
Use of a Hotplate at 80°C for 3 minutes to help Fixation of Histological Preparations Burhannudin; Herbyananda, Arnando Daffa
Biomedika Vol 16, No 2 (2024): Biomedika Agustus 2024
Publisher : Universitas Muhammadiyah Surakarta

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Abstract

Fixation is a complex stage and requires a long time. The microwave heating process has been proven to accelerate the fixation rate, but the use of a hotplate in helping the fixation process has yet to be discovered. The study aims to determine the optimal time of 80°C hotplate heating in helping fixation. The study was conducted experimentally using a post-test only control group design. A total of 75 histological slides of hepatic tissue of male Wistar rats were divided into five groups with equal size: control group (conventional/K and microwave/M) and three treatments of 80°C hotplate for 3 minutes (H1), 5 minutes (H2) and 10 minutes (H3). Hematoxylin Eosin (HE) staining results of all histology slides were morphologically observed and scored based on previous studies. In addition, the staining scores were tested for differences between groups using the Kruskal-Wallis and Mann-Whitney tests, with p values <0.05 being significant. The results of morphological observations of HE stains stated that the median H2 group was worth a score of 3, while the other groups were worth a score of 2. The results of the Kruskal-Wallis and Mann-Whitney tests showed that the H2 group significantly differed from the control group (p<0.05). This shows that using a hotplate at 80 ° C for 5 minutes can help the fixation process in making histological preparations of rat hepatic tissue.
The Effect of Robusta Coffee (Coffea canephora) on the Expression of SOD and Nrf-2 in Diabetes Mellitus condition (Animal Model) Sofyanita, Eko Naning; Maulana, Mochamad Rizal; Lestari, Puji; Burhannudin
Poltekita: Jurnal Ilmu Kesehatan Vol. 18 No. 3 (2024)
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v18i3.3753

Abstract

Hyperglycemia is a condition that occurs when Diabetes Mellitus (DM) is uncontrolled, which causes an increase in free radicals and disruption of cell function and endogenous antioxidants. Coffee, especially robusta coffee, is known to have benefits as an exogenous antioxidant that can increase the activity of endogenous. This study aims to examine the effect of giving robusta coffee on the expression of Nuclear Factor-erythroid-2 Related Factor 2 (Nrf-2) and Superoxide Dismutase (SOD) in DM model mice. The design of this study was experimental with the Post Test Control Group Design method. A total of 24 male Rattus norvegicus mice aged 3 months with a body weight of 230-250 grams were randomly divided into four groups. After undergoing acclimatization for one week, the mice were given robusta coffee once a day for 14 days. On the 15th day, Nrf-2 and SOD expression were examined. The results showed that the average expression of Nrf-2 in each group was: 23.15 ± 1.96 (normal group/KN), 62.14 ± 1.30 (positive DM group/KP), 50.66 ± 2.18 (DM group with low dose coffee/KK1), and 71.13 ± 1.51 (DM group with high dose coffee/KK2). Meanwhile, SOD expression was: 4.95 ± 0.62 (KN), 8.14 ± 0.54 (KP), 6.10 ± 0.79 (KK1), and 9.26 ± 0.31 (KK2). The results of the ANOVA and Post Hoc LSD tests showed a p value <0.05, which indicated a significant difference between groups. In conclusion, administration of robusta coffee (Coffea canephora) was able to increase the activity of the Nrf-2 and SOD enzymes in mice suffering from diabetes mellitus.
Co-Authors Alpia Rahmah Dewa Ayu Intan Puspita Dewi Eko Naning Sofyanita Herbyananda, Arnando Daffa I Waya Merta I Wayan Merta Kurniaty Kurniaty Maulana, Mochamad Rizal Mustaghfiri Abdan Ni Made Dwijayanti PUJI LESTARI Sri Bulkia