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All Journal TELKOMNIKA (Telecommunication Computing Electronics and Control) Jurnal Riset Kesehatan Berkala Ilmu Kesehatan Kulit dan Kelamin Global Medical and Health Communication Jurnal Imejing Diagnostik Health Notions Biomolecular and Health Science Journal Indian Journal of Forensic Medicine & Toxicology PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS (COMORBID) Folia Medica Indonesiana
Ferriastuti, Widiana
Department Of Radiology, Faculty Of Medicine Universitas Airlangga, Surabaya, Indonesia - Dr. Soetomo General Hospital Surabaya
Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Biomolecular and Health Science Journal

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Head Computed Tomography Images of HIV/AIDS Patients with Suspected Cerebral Toxoplasmosis in Dr. Soetomo General Hospital Surabaya Ria Wibawani; Bambang Soeprijanto; Widiana Ferriastuti; Erwin A Triyono
Biomolecular and Health Science Journal Vol. 2 No. 1 (2019): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (257.739 KB) | DOI: 10.20473/bhsj.v2i1.13343

Abstract

Introduction: Toxoplasma gondii is an intracellular pathogenic parasite with the majority of co-infections occurring in HIV/AIDS patients. This study assesses the head computed tomography (CT) images of cerebral toxoplasmosis in patients with HIV/AIDS.Methods: This study was a cross-sectional design using head CT images of 35 HIV/AIDS patients with suspected cerebral toxoplasmosis. Variables include lesion type, location, size, CD4 count, and therapeutic result with anti-cerebral toxoplasmosis. All data analysed descriptively.Results: From total 110, 35 patients met the inclusion criteria. 24 patients (68.6%) were male and 11 (31.4%) female, average age, was 36.1. 8 patients (22.3%) had lesions in cortical, 31 patients (88.6%) had < 1 cm lesion. Single lesions mainly calcified and found in the right centrum semiovale while multiple lesions were subcortical. A hypodense lesion with rim or nodular contrast enhancement is found in 75% of patients with CD4 > 200 in contrast to slight rim contrast enhancement and perifocal edema in patients with CD4 < 200. 20 patients (57.4%) had improved condition after anti-toxoplasmosis therapy.Conclusion: Cerebral toxoplasmosis lesions in HIV/AIDS patients have various types of imaging findings, mostly multiple, with most frequent location being cortical and diameter < 1 cm. Total recovery is achieved in the majority of patients with therapy.
The Correlation between Apparent Diffusion Coefficient Value on MRI and the Pathology Consistency of Meningioma Wyka Faulani Hafizah Nur; Widiana Ferriastuti; Bambang Soeprijanto
Biomolecular and Health Science Journal Vol. 3 No. 2 (2020): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bhsj.v3i2.22171

Abstract

Introduction: Preoperative evaluation of meningioma consistency is important because it will affect surgical procedures, surgical optimization, risk assessment, and patient management. The consistency of meningioma can be predicted by Apparent Diffusion Coefficient (ADC) value on MRI. ADC values are useful in quantitative tumor assessment based on diffusivity in the tumor. The objective of the study is to find out the correlation between ADC value and the pathology consistency of meningioma.Methods: A retrospective study was carried out using medical records at Dr. Soetomo General Hospital, Surabaya by January 2017 - December 2018. The ADC value was obtained by placing three ROI in the tumor and the consistency was obtained from the results of the pathology examination, followed by the Spearman correlation test.Results: There The tumor range value of ADC was 0.58 x 10-3mm2 s to 1.63 x 10-3mm2/s. The mean ADC value in soft, intermediate, and hard consistency was 1.247+ 0.200 x 10-3mm2/s, 0.950 + 0.453 x 10-3mm2/s, and 0.793 + 0.161 x 10-3mm2/s, the cut-off value of ADC was + 0.822 x 10-3mm2/s with specificity 68% and sensitivity 85%, the AUC is 0.740 with a significance value of 0.0043 (p<α, α = 0.05). It was obtained an ADC correlation with the consistency of meningioma, the significance value is p=0.000 (p<α, α = 0.05).Conclusion: There is a correlation between the ADC value and the consistency of meningioma. The ADC value can be considered for an optimal preoperative evaluation in assessing the consistency of meningioma.
Co-Authors Agus Setyo Kiswoyo Almuhayar, Mawanda Anindya Apriliyanti Pravitasari Bambang Soeprijanto Cita Rosita Sigit Prakoeswa Distyarini Primadita Dwi P. R. Tampubolon Erwin A Triyono Faradilla litiloly1, Hartono Yudi Sarastika1 Fithriasari, Kartika Gatot Murti Wibowo Ida Bagus Ramayuda Irhamah - Jannah, Marichatul Leon Agung Manurung Ni'ami, Muhamad Aufa Nur Iriawan Paulus Rahardjo, Paulus Prameswari, Faida Ufaira Qonita Qonita Ramayuda, Ida Bagus Ria Wibawani Rini Indrati Rosyidi, Muhammad Yunus Santi Wulan Purnami Siti Daryati Sri Mulyati Taufik Azmi Widodo Widodo Wyka Faulani Hafizah Nur