Article Per Year (5 Year)
p-Index From 2020 - 2025
0
P-Index
This Author published in this journals
All Journal Jurnal Fitofarmaka Indonesia
Sri Amalia
Fakultas Kedokteran Universitas Tanjungpura
Biochemistry, Genetics & Molecular Biology Chemistry Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
UJI AKTIVITAS ANTIBAKTERI FRAKSI n-HEKSAN KULIT BUAH NAGA MERAH (Hylocereus polyrhizus Britton & Rose) TERHADAP BAKTERI Staphylococcus aureus ATCC 25923 Sri Amalia; Sri Wahdaningsih; Eka Kartika Untari
Jurnal Fitofarmaka Indonesia Vol 1, No 2 (2014): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (763.312 KB) | DOI: 10.33096/jffi.v1i2.191

Abstract

Inappropiate antibiotic use was one of the main reason that caused pathogenic microorganism resistance, leads to ineffective treatment. One of those resistance bacteria is Staphylococcus aureus. The research for discovering new antibiotics can help with this issue. The peel of red dragon fruit (Hylocereus polyrhizus) is one of the plants that has antibacterial compounds. The aim of this research is to prove and determine the minimum inhibitory concentration (MIC) value of n-hexane fraction of red dragon fruit’s peel againts Staphylococcus aureus ATCC 25923. The peel was maserated with chloroform, then fractinated by n-hexane. Futhermore, the antibacterial properties of the fraction was tested using Disc Diffusion (Kirby-Bauer) methode with 40, 20 dan 10 mg/mL concentrations. Ampisilin used as control positive. Based on the phytochemical screening of the fraction, the n-hexane fraction of the dragon fruit’s peel contain triterphenoid, steroid and alkaloid. Clear zones produced by 40 mg/mL is 12,80 mm and for 20 mg/mL is 11,17 mm. Wherea concentration 10 mg/mL didn’t show any inhibitory zone. According to this reasearch, the MIC value of the fraction is  20 mg/mL.
Co-Authors Eka Kartika Untari Sri Wahdaningsih