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All Journal E-Jurnal Medika Udayana JBN (Jurnal Bedah Nasional) Majalah Patologi Indonesia The International Journal of Medical Science and Health Research
I Made Darmajaya
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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DIAGNOSTIC METHOD OF HIRSCPRUNG’S DISEASE I Putu Trisnawan; I Made Darmajaya
E-Jurnal Medika Udayana vol 2 no5(2013):e-jurnal medika udayana
Publisher : Universitas Udayana

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Abstract

Hirschsprung’s disease (congenital megacolon) is caused by the failed migration of colonic ganglion cells during gestation. Hirschsprung’s disease most commonly involves the rectosigmoid region of the colon but can affect the entire colon and, rarely, the small intestine. Symptoms in infants include difficult bowel movements, poor feeding, poor weight gain, and progressive abdominal distention. Early diagnosis is important to prevent complications (e.g., enterocolitis, colonic rupture). With proper treatment, most patients will not have long-term adverse effects and can live normally.
ATRESIA DUODENAL, DIAGNOSIS AND TREATMENT I Dewa Ayu Widiastuti; I Made Darmajaya
E-Jurnal Medika Udayana vol 2 no5(2013):e-jurnal medika udayana
Publisher : Universitas Udayana

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Duodenal atresia is a condition where the duodenum is not well developed. Atresia Duodenal is an obstruction that often occur in the neonate after birth.  Atresia occurs in 1 of 1000 births. Intestinal Atresia may occur at various places in the small intestine. 50% of cases of intestinal atresia occurs in the duodenum. Symptoms are often caused the bowel obstruction. Symptoms will appear within 24 hours after birth. Continuous vomiting are the most frequent symptoms. If the child's condition is not treated quickly, the child will experience dehydration, weight loss, electrolyte balance disorders. If dehydration is not treated, it can happen or hipokloremia hypokalemic metabolic alkalosis. On physical examination found  abdominal distension. Investigations at the prenatal period by using prenatal ultrasonography. Investigations that postnatal use a x-ray. X-ray examination of the first by the plain abdominal x-ray. X-ray image shows the double-bubble sign without gas in the distal colon. Management options include menagement preoperative, intraoperative and postoperative management. Life expectancy for infants with duodenal atresia which is 90-95%. Mortality is high due to prematurity and multiple congenital abnormalities.  
TEKNIK OPERASI DUA TAHAP PADA KASUS PENYAKIT HIRSCHSPRUNG DIAGNOSIS TERLAMBAT DI RSUP SANGLAH: 1 STUDI DESKRIPTIF TAHUN 2010-2012 Putu Dewi Octavia; I Made Darmajaya
E-Jurnal Medika Udayana vol 3 no 8 (2014):e-jurnal medika udayana
Publisher : Universitas Udayana

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Abstract

Latar Belakang: Penelitian ini bertujuan untuk mengetahui bagaimana diagnosistertunda pada pasien Hirschsprung di RSUP Sanglah serta masing-masing proporsiteknik operasi dua tahap pada pasien Hirschsprung diagnosis tertunda dihitung daritahun 2010 sampai 2012.Metode: Penelitian ini merupakan potong lintang deskriptif dengan data yangdigunakan bersumber dari data sekunder yang diperoleh dari hasil pencatatan pasienpenyakit Hirschsprung di RSUP Sanglah tahun 2010 sampai 2012.Hasil: Dari 102 kasus Hirschsprung pada tahun 2010 sampai 2012, 76 pasien dilakukanpenanganan dengan teknik operasi dua tahap. Proporsi penanganan pasien Hirschsprungmasing-masing tahun didominasi dengan teknik operasi dua tahap. Teknik operasi duatahap yang digunakan paling banyak adalah Duhamel Stapler.Kesimpulan: Pasien Hrischsprung dengan diagnosis tertunda memiliki proporsi lebihbanyak dibandingkan Hirschsprung diagnosis dini. Teknik operasi dua tahap lebihbanyak dikerjakan mengikuti diagnosis penyakit Hirschsprung diagnosis terlambat.
Validity of Barium Enema as Hirschsprung’s Disease Diagnostic Tools for Infant in Sanglah Hospital Denpasar I Made Darmajaya; I Ketut Subhawa
JBN (Jurnal Bedah Nasional) Vol 5 No 1 (2021): JBN (Jurnal Bedah Nasional)
Publisher : Program Studi Ilmu Bedah, Fakultas Kedokteran Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JBN.2021.v05.i01.p03

Abstract

Aim: To determine the validity (sensitivity, specificity, likelihood ratio) of barium enema as Hirschsprung's disease diagnostic tool in infants. Methods: This study was a diagnostic test of barium enema compared with postoperative histopathology examinations as the gold standard. The population were all patients with indigestion symptom be discovered at the pediatric surgical clinic of Sanglah Hospital Denpasar. The sampling method was consecutive sampling, satisfy inclusion criteria (< 12 months old, indicate classic symptoms of Hirschsprung’s disease). The total sample of the study was 52 patients. Sensitivity, specificity, positive and negative predictive value were analysed using cross-tabulation test of barium enema and postoperative histopathology. Results: A total of 52 patients were evaluated during the study period, mean of age was 3.31 months old, and boys:girls (75%:25%). Based on symptoms, 98.08% of patients were delayed release of meconium more than 24-48 hours and abdominal distention. Among all the patients reviewed, sensitivity, specificity, positive and negative predictive value of barium enema for diagnostic of Hirschsprung’s disease was 95.5%, 87.5%, 97.7%, and 77.8%. Conclusion: Barium enema can be used as an early diagnostic tool for infants suspected of Hirschsprung’s disease.
The Analysis Study of Diagnosis and Management of Giant Omphaloceles: A Comprehensive Systematic Review Risko Sandy; I Gusti Agung Ngurah Maha Yudha; I Made Darmajaya
The International Journal of Medical Science and Health Research Vol. 6 No. 1 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/16yqzc19

Abstract

Background: Giant omphalocele (GO) is a severe form of omphalocele, characterized by a defect larger than 5 cm, often including the liver. Management strategies include staged surgical closure and non-operative delayed closure, with the latter focusing on neo-epithelialization and secondary operations. This study aims to explore diagnosis and management during neonatal care. Methods: This systematic review exclusively examined full-text articles published in English between 2014 and 2024, adhering to the PRISMA 2020 guidelines. Result: The study conducted a thorough review of more than 300 publications that were obtained from reputable databases, such as ScienceDirect, SagePub, and PubMed. Eight publications were identified as necessitating a more comprehensive examination subsequent to an initial screening. As a result, a comprehensive review of these selected studies was conducted to guarantee an exhaustive and rigorous assessment. Conclusion: Giant omphaloceles management involves a multifaceted approach, including primary closure, staged surgical closure, and nonoperative delayed closure. Synthetic materials and biological meshes promote granulation tissue formation and gradual closure, but further research is needed to reduce morbidity and mortality.
Combination of Urachal and Omphalomesenteric Duct Remnant: A Rare Case Reports Maker, Luh Putu Iin Indrayani; Manna, Johana Sensy Leni; Darmajaya, I Made
Majalah Patologi Indonesia Vol. 33 No. 1 (2024): MPI
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v33i1.645

Abstract

Umbilical problems encountered in the pediatric population are often associated with retained umbilical cord structures or with failure of the umbilical ring to close at birth. This article reported a case of umbilical anomalies in 3-years old male, with a chief complaint of a lump on the umbilical area a urinary discharge from the umbilical since birth. Incidence of patent vitelointestinal duct (omphalomesenteric duct) varies from 1 in 5000-8000 while patent urachus are still rare, ranging from 1-2 per 100000. The combination of both anomalies is very rare, only 12 reported cases since 1898 until 2016. Ultrasound can play an important diagnostic role for these types of anomalies if performed by expert. In our case, the ultrasound was not able to confirm the diagnosis due to a lot of gas in the abdomen. Based on clinical data and histopathologic examination, the patient was diagnosed with combination of urachal and omphalomesenteric duct remnant.
Co-Authors I Dewa Ayu Widiastuti I Gusti Agung Ngurah Maha Yudha I Ketut Subhawa I Putu Trisnawan Maker, Luh Putu Iin Indrayani Manna, Johana Sensy Leni Putu Dewi Octavia Risko Sandy