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Knowledge, Attitude, and Behavior Level of Women of Reproductive Age toward Calcium Intake Kartika Ratna Dewi; Eva M. Hidayat; Anita Rachmawati
Althea Medical Journal Vol 5, No 1 (2018)
Publisher : Faculty of Medicine Universitas Padjadjaran

Background: Women have a higher risk of developing osteoporosis compared to men. Calcium intake is one of the determinant factor which can be modified to prevent osteoporosis. Knowledge, attitude and behaviour are important factors to fulfill the needs of calcium intake. This study aimed to describe knowledge, attitude, and behavior toward calcium intake of woman of reproductive age.Methods: This descriptive study recruited 100 women (aged 20–30 years) in Jatinangor, West Java and was conducted from September to November 2014. Knowledge and attitude measurements used a validated questionnaire consisting of 10 and 9 closed questions respectively. Behavioral aspect was assessed using semi-quantitative Food Frequency Questionnaire (FFQ). Knowledge was classified as high, moderate, and low based on questionnaire scoring results, >75%, 60–75%, and <60% respectively. Attitude was categorized in two: positive and negative. Behaviour category used Recommended Dietary Allowances (RDA) as the cut-off point. If the daily calcium intake is below the RDA it is categorized less and if the daily calcium intake equals to or exceeds the RDA it is categorized sufficient. The collected data were presented in frequency tabulation and percentage.Results: The majority of subjects showed low to moderate level of knowledge toward calcium intake, 66% of subjects showed negative attitude towards calcium intake, and 98% showed calcium intake below the RDA. Conclusions: Subjects of this study have low to moderate level of knowledge, negative attitude toward calcium intake, and low level of behavior toward calcium intake.

Karakteristik Ibu Hamil dengan HIV/AIDS di RSUP Dr. Hasan Sadikin Bandung Periode 2014 ̶ 2016 Romy Ade Putra; Hadi Susiarno; Anita Rachmawati; Windi Nurdiawan
Indonesian Journal of Obstetrics & Gynecology Science Volume 1 Nomor 2 September 2018
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

AbstrakTujuan: Untuk mengetahui karakter HIV/AIDS selama kehamilan di Rumah Sakit Dr. Hasan Sadikin Bandung sejak Januari 2014 sampai Desember 2016.Metode: Studi retrospektif terhadap HIV/AIDS selama kehamilan di Klinik Rawat Jalan Teratai di Rumah Sakit Dr. Hasan Sadikin Bandung, dengan mengumpulkan data dari rekam medis pasien baru mulai bulan Januari 2014 sampai Desember 2016. Ciri khasnya adalah usia, pekerjaan, tingkat pendidikan, cara transmisi, tempat tinggal, status perkawinan dan sejarah pengobatan anti retroviral.Hasil: Terdapat 102 kasus wanita hamil dengan HIV/AIDS sejak Januari 2014 sampai Desember 2016. Sebagian besar kasus ditemukan pada usia 30-39 tahun, 63 kasus (61,8%). 69 (67,6%) pasien adalah ibu rumah tangga. Sebanyak 55 (53,9%) pasien telah menyelesaikan sekolah menengah atas. Sebagian besar kasus adalah transmisi heteroseksual 95 (93,13%) dan 96 (94,1%) pasien sudah menikah.Kesimpulan: Terdapat perubahan karakteristik wanita hamil dengan infeksi HIV / AIDS di Rumah Sakit Dr.Hasan Sadikin Bandung.The Characteristics of Pregnant Women with HIV/AIDS Infection in Dr. Hasan Sadikin General Hospital Bandung in 2014−2016AbstractObjective: To find the characterics of HIV/AIDS during pregnancy in Dr. Hasan Sadikin Hospital Bandung since January 2014 to December 2016.Method: Retrospective study of HIV/AIDS during pregnancy in Teratai Outpatient Clinic of Dr.HasanSadikin Hospital Bandung, by collecting data from the medical record of new patients from January 2014 to December 2016. The characteristics are age, occupation, education level, mode of transmission, residence, marital status and history of anti retroviral treatment.Result: there are 102 cases of pregnant women with HIV/AIDS since January 2014 to December 2016. The most cases are found in 30-39 years old, 63 cases (61.8%). 69 (67.6%) patients are housewife. 55 (53.9%) patients had completed senior high school. The most cases are heterosexual transmission 95 (93.13%). 96 (94.1%) patients are married.Conclusion: There are changes in characteristics of pregnant women with HIV infection /AIDS in Dr.Hasan Sadikin Hospital Bandung.Key words: HIV/AIDS, pregnancy

Primary Umbilical Endometriosis Presenting as Cyclic Umbilical Bleeding: A Case Report with Preoperative Dienogest Therapy Anna Theresia Regina Ritonga; Anita Rachmawati; Dian Tjahyadi; Ruswana Anwar
Indonesian Journal of Obstetrics & Gynecology Science Volume 9s Number 2 July 2026 Special Issue Case Report & Systematic Review
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v9i2.1084

Introduction: Endometriosis is a chronic inflammatory gynecologic disease characterized by the presence of endometrial-like tissue outside of the uterus, most commonly on pelvic organs, affecting approximately 10% of women and girls of reproductive age worldwide. Umbilical endometriosis, also known as Villar’s nodule, is a rare form of endometriosis characterized by the presence of endometrial tissue in the umbilicus, with an incidence approximately 0.5% to 1% of all endometriosis cases worldwide.Case Report: A 36-year-old woman, P2A0, presented with a slowly enlarging umbilical nodule for 8 months, accompanied by pain and cyclic menstrual bleeding, with no history of abdominal surgery. Physical examination revealed a blackish-brown umbilical nodule measuring 2.5×3×1cm. A previous biopsy confirmed external endometriosis. Administration of dienogest at a dose of 2 mg/day for three months resulted in a favorable therapeutic response, as evidenced by clinical improvement and a reduction in lesion size to 1.5×1.5cm. The patient subsequently underwent surgical excision, and histopathological examination confirmed umbilical endometriosis. Dienogest therapy was continued for six months postoperatively, with no evidence of recurrence during follow-up.Conclusion: Primary umbilical endometriosis is a rare type of endometriosis and dienogest can be used as pretreatment before surgery.Endometriosis Umbilikalis Primer dengan Manifestasi Perdarahan Siklik dari Umbilikus: Laporan Kasus dengan Terapi Dienogest PreoperatifAbstrakPendahuluan: Endometriosis adalah penyakit inflamasi ginekologis kronis yang ditandai dengan jaringan mirip endometrium di luar rahim, paling sering pada organ panggul yang memengaruhi sekira10% wanita dan anak perempuan usia reproduksi di seluruh dunia. Endometriosis umbilikalis juga dikenal sebagai nodul Villar, adalah bentuk endometriosis langka yang ditandai dengan adanya jaringan endometrium di umbilikus, dengan insiden 0,5% hingga 1% dari semua kasus endometriosis di seluruh dunia.Laporan kasus: Seorang wanita berusia 36 tahun, P2A0, datang dengan nodul umbilikalis yang membesar perlahan selama 8 bulan, disertai nyeri dan perdarahan menstruasi siklik, tanpa riwayat operasi perut. Pemeriksaan fisik menunjukkan nodul umbilikalis berwarna coklat kehitaman berukuran 2,5×3×1cm. Biopsi sebelumnya mengonfirmasi endometriosis eksternal. Pemberian dienogest 2mg/hari selama tiga bulan menghasilkan respons terapi yang baik, yang ditunjukkan oleh perbaikan klinis dan penyusutan ukuran lesi menjadi 1,5×1,5 cm. Setelah itu, pasien menjalani eksisi bedah, dengan hasil histopatologi yang mengonfirmasi endometriosis umbilikalis. Terapi dienogest dilanjutkan selama enam bulan pascaoperasi, dan pada evaluasi lanjutan tidak ditemukan tanda-tanda kekambuhan.Kesimpulan: Endometriosis umbilikal primer adalah jenis endometriosis yang langka dan dienogest dapat digunakan sebagai pengobatan pendahuluan sebelum pembedahan.

Mosaic Turner Syndrome and Hypogonadotropic Hypogonadism in a 17-Year-Old Female: A Diagnostic Dilemma with Possible Kallmann Syndrome Muhammad Alif; Artha Falentin Putri Susilo; Hanom Husni Syam; Dian Tjahyadi; Anita Rachmawati
Indonesian Journal of Obstetrics & Gynecology Science Volume 9s Number 2 July 2026 Special Issue Case Report & Systematic Review
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v9i2.1085

Introduction: Primary amenorrhea, defined as the absence of menstruation by age 15, has a broad differential diagnosis, including anatomical, endocrine, hypothalamic-pituitary, and genetic causes. Turner syndrome and Kallmann syndrome are two distinct etiologies with different pathophysiological mechanisms. Turner syndrome is characterized by hypergonadotropic hypogonadism due to gonadal dysgenesis, whereas Kallmann syndrome results from gonadotropin-releasing hormone (GnRH) deficiency and is often associated with anosmia.Case Presentation: A 17-year-old female was referred with primary amenorrhea and absent secondary sexual development. Physical examination revealed Tanner Stage I breast and pubic hair development, with no reported olfactory disturbances. Hormonal assays indicated hypogonadotropic hypogonadism, with low FSH, LH, and estradiol levels. Pelvic ultrasonography revealed a hypoplastic uterus and non-visualized ovaries. Cranial MRI showed pituitary hypoplasia and bilateral agenesis of the olfactory bulbs, suggestive of Kallmann syndrome. However, karyotype analysis revealed a mosaic 45,X/46,XX pattern, consistent with Turner syndrome. This combination of clinical, hormonal, imaging, and cytogenetic findings posed a unique diagnostic dilemma.Discussion: The overlapping features of Turner and Kallmann syndromes make this case highly unusual. Turner syndrome typically presents with hypergonadotropic hypogonadism, whereas Kallmann syndrome is characterized by hypogonadotropic hypogonadism, often with anosmia. Comprehensive evaluation, including cytogenetic analysis and MRI, was essential for accurate diagnosis. Management focused on pubertal induction with hormone replacement therapy and appropriate genetic and systemic evaluation.Conclusion: This case underscores the diagnostic complexity of primary amenorrhea with overlapping features of Turner and Kallmann syndromes. Accurate diagnosis requires integrated hormonal, imaging, and cytogenetic evaluation, with management focused on hormonal correction and long-term supportive care.

A Systematic Review Of The Factors Influencing Successful Vaginal Birth After Cesarean Fatimah Azzahra; Sri Endah Rahayuningsih; Anita Rachmawati; QORINAH ESTININGTYAS SAKILAH ADNANI; VICTOR ABIOLA ADEPOJU
Jurnal Kesehatan Masyarakat Vol. 21 No. 3 (2026)
Publisher : Universitas Negeri Semarang in collaboration with Ikatan Ahli Kesehatan Masyarakat Indonesia (IAKMI Tingkat Pusat) and Jejaring Nasional Pendidikan Kesehatan (JNPK)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v21i3.22873

Background: This systematic review explores factors influencing the success of Vaginal Birth After Cesarean (VBAC) in response to increasing global cesarean rates. VBAC reduces the need for repeat cesareans and associated risks. Purpose: To identify key medical, psychological, and institutional factors affecting VBAC outcomes. Methods: A total of 21 studies were reviewed from PubMed, ScienceDirect, and Google Scholar using PRISMA-ScR criteria. The analysis focused on maternal age, previous vaginal birth, cervical dilatation, healthcare access, and psychosocial support. Results: Successful VBAC was linked to younger maternal age, prior vaginal birth experience, spontaneous labor onset, and adequate cervical dilatation at admission. Psychosocial support, including family encouragement and professional guidance, significantly influenced VBAC decisions. Hospital policies promoting VBAC and ensuring access to emergency services further enhanced success rates. Conclusion: Medical, social, and institutional factors significantly affect VBAC success. Establishing standardized guidelines and providing improved counseling are essential to support women’s choices during childbirth. Future research should focus on large, diverse populations to confirm predictors and assess long-term outcomes compared to repeat cesareans.

The Role of Neuron Growth Factor and Interleukin-10 in The Development of Pain in Adenomyosis: A Narrative Review Agus Heriyanto; Dian Tjahyadi; Anita Rachmawati; Luky Adlino
Indonesian Journal of Obstetrics & Gynecology Science Volume 8 Nomor 3 November 2025
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v8i3.931

Introduction: Adenomyosis, a benign uterine condition characterized by endometrial tissue within the myometrium, leads to uterine enlargement, infertility, dysmenorrhea, and heavy menstrual bleeding. While its precise etiology remains elusive, delayed pregnancy may contribute to its increasing incidence among infertile women. This condition, predominantly affecting parous women, is also associated with higher rates of early miscarriage. Although immune dysregulation in endometriosis is well-documented, comparable research in adenomyosis is limited.Objective: This review aims to explore the roles of Interleukin-10 (IL-10), an anti-inflammatory cytokine, and Neuronal Growth Factor (NGF), a neuroimmune factor, in adenomyosis.Discussion: Elevated IL-10 levels in ectopic endometrial tissue suggest a potential immunosuppressive mechanism that may exacerbate symptoms. NGF is also implicated in the pain and inflammation associated with adenomyosis. A deeper understanding of the interplay between IL-10 and NGF could offer critical insights into the inflammatory nature and pain mechanisms of this condition.Conclusion: This review proposes IL-10 as a potential inflammatory biomarker and NGF as a pain marker in adenomyosis, paving the way for future research into novel therapeutic targets. Elucidating these pathways could lead to treatments focused on mitigating inflammation and alleviating associated symptoms of adenomyosis.Keywords: adenomyosis; neuronal growth factor; interleukin-10; pelvic pain Peran Neuron Growth Factor (NGF) dan Interleukin-10 (IL-10) dalam pembentukan Nyeri pada Adenomyosis : Sebuah Review NaratifAbstrakPendahuluan: Adenomyosis, suatu kondisi rahim jinak yang ditandai dengan adanya jaringan endometrium di dalam miometrium, menyebabkan pembesaran rahim, infertilitas, dismenore, dan perdarahan menstruasi yang berat. Meskipun etiologi pastinya masih belum jelas, kehamilan yang tertunda kemungkinan berkontribusi pada peningkatan insidennya di kalangan wanita infertil. Kondisi ini, yang sebagian besar memengaruhi wanita multipara, juga dikaitkan dengan tingkat keguguran dini yang lebih tinggi. Meskipun disregulasi imun pada endometriosis telah didokumentasikan dengan baik, penelitian serupa pada adenomyosis masih terbatas.Tujuan: Tinjauan ini bertujuan untuk mengeksplorasi peran Interleukin-10 (IL-10), sitokin anti-inflamasi, Faktor Pertumbuhan Saraf (NGF) dan faktor neuroimun dalam adenomyosis.Diskusi: Peningkatan kadar IL-10 dalam jaringan endometrium ektopik menunjukkan mekanisme imunosupresif potensial yang dapat memperburuk gejala. NGF juga berperan dalam nyeri dan peradangan yang terkait dengan adenomyosis. Pemahaman yang lebih dalam tentang interaksi antara IL-10 dan NGF dapat memberikan wawasan penting mengenai sifat inflamasi dan mekanisme nyeri dari kondisi ini.Kesimpulan: Tinjauan ini mengusulkan IL-10 sebagai biomarker inflamasi potensial dan NGF sebagai penanda nyeri pada adenomyosis. Hal tersebut membuka jalan bagi penelitian lebih lanjut untuk target terapeutik baru. Menguraikan jalur-jalur ini dapat mengarah pada perawatan yang berfokus pada mitigasi peradangan dan mengurangi gejala adenomyosis.Kata kunci: adenomiosis; interleukin-10; neuronal growth factor; nyeri pelvis.

Characteristics of Patients with Diminished Ovarian Reserve Undergoing in Vitro Fertilization (IVF) at Hasan Sadikin Hospital from 2019-2023 Iqbal Anugrah Fitriyanto; Anita Rachmawati; Akhmad Yogi Pramatirta
Indonesian Journal of Obstetrics & Gynecology Science Volume 8 Nomor 3 November 2025
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v8i3.1004

Objective: This study aimed to describe the characteristics of patients with diminished ovarian reserve undergoing in vitro fertilization (IVF) to improve understanding of its implications for infertility.Methods: Cross-sectional descriptive study using medical records of patients who underwent IVF at Dr. Hasan Sadikin General Hospital (RSHS) from 2019 to 2023. Analyzed variables included age, education level, occupation, duration of marriage, body mass index, Anti-Müllerian hormone (AMH) level, and ovarian stimulation protocol.Results: A total of 57.14% of the 55 patients were aged 35 – 40 years, 87.5% nulliparous, and 55.36% had a body mass index greater than 24.9 kg/m2. The percentage that held a bachelor’s degree was 64.29%, and 55.36% had AMH levels below 1.1 ng/ml. A total of 78.57% received a short stimulation protocol, and 21.43% received a long stimulation protocol.Conclusion: Most patients with diminished ovarian reserve undergoing IVF at RSHS (2019 – 2023) were aged 35 – 40, nulliparous, obese class I–II, AMH value <1.1 ng/ml, and were subjected to a short IVF protocol.Karakteristik Pasien dengan Diminished Ovarian Reserve yang Melakukan In Vitro Fertilization (IVF) di Rumah Sakit Hasan Sadikin pada Tahun 2019 – 2023AbstrakTujuan: Penelitian ini bertujuan menggambarkan karakteristik pasien dengan cadangan ovarium menurun yang menjalani fertilisasi in vitro untuk meningkatkan pemahaman tentang implikasi cadangan ovarium menurun pada infertilitas.Metode: Metode yang digunakan dalam penelitian ini adalah deskriptif observasional potong lintang yang menggunakan data rekam medis pasien yang menjalani fertilisasi in vitro di Rumah Sakit Hasan Sadikin (RSHS) periode 2019 – 2023. Variabel yang dianalisis meliputi usia, tingkat pendidikan, pekerjaan, lama menikah, indeks massa tubuh, kadar hormon anti-Müllerian, dan protokol stimulasi ovarium.Hasil: Hasil penelitian menunjukkan bahwa dari 55 pasien, 57,14% berusia 35 – 40 tahun, 87,5% belum pernah melahirkan, 55,36% memiliki indeks massa tubuh lebih dari 24,9 kg/m2, 64,29% berpendidikan sarjana, dan 55,36% memiliki kadar hormon anti-Müllerian kurang dari 1,1 ng/ml. Sebanyak 78,57% menjalani protokol stimulasi pendek dan 21,43% menjalani protokol stimulasi panjang.Kesimpulan: Sebagian besar pasien dengan cadangan ovarium menurun yang menjalani fertilitasi in vitro di RS Dr. Hasan Sadikin (201 – 2023) berusia 35 – 40 tahun, nullipara, obesitas kelas I–II, nilai AMH <1.1 ng/ml dan menjalani protokol IVF pendek.Kata kunci: Anti-mullerian hormone; diminished ovarian reserve; FSH; infertilitas; in vitro fertilization (IVF), teknologi reproduksi berbantu

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