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All Journal International Journal of Integrated Health Sciences Althea Medical Journal Paediatrica Indonesiana
Tetty Yuniati
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Health Professions Medicine & Pharmacology

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Characteristics of Neonatal Hyperbilirubinemia at West Java’s Top Referral Hospital, Indonesia. Nurain Yahya; Tetty Yuniati; Leonardo Lubis
Althea Medical Journal Vol 4, No 2 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (205.312 KB) | DOI: 10.15850/amj.v4n2.1065

Abstract

Background: Neonatal hyperbilirubinemia or neonatal jaundice is a common disorder and considered as one of the main problems in neonatal period worldwide with high incidence, especially in Asia and Southeast Asia region. This study was conducted to determine the characteristics of neonatal hyperbilirubinemia including the prevalence and frequency of neonatal hyperbilirubinemia causes at Dr. Hasan Sadikin General Hospital in 2012.Methods: This descriptive study was conducted at Dr. Hasan Sadikin General Hospital using the cross-sectional method. Four hundred and twenty five cases of neonatal hyperbilirubinemia in hospitalized and outpatients, from 1 January to 31 December 2012 were included in this descriptive study.Results: The prevalence of neonatal hyperbilirubinemia was about 4.08%. Causes were identified in 95 cases and the most common cause of neonatal hyperbilirubinemia during this period of time was physiological causes (23.2%). Other causes included neonatal hepatitis (14.7%), other hemolytic causes (13.7%), infection (12.6%), ABO incompatibility (11.6%) and breastfeeding (11.6%).Conclusions: Neonatal hyperbilirubinemia cases are common and remain as one of the neonatal problems in Dr. Hasan Sadikin General Hospital, thus prevention and proper management of neonatal hyperbilirubinemia should be implemented. DOI: 10.15850/amj.v4n2.1065
NR2B Gene Expression Change in Wistar Rat Practicing Aerobic Exercise Comparing to Soybean (Glycine max) or Phyllanthus niruri Intakes and Soybean and Phyllanthus niruri Composition Intake Vita Muniarti Tarawan; Diah Dhianawaty; Tetty Yuniati; Muhamad Nurhalim Shahib
International Journal of Integrated Health Sciences Vol 3, No 2 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3012.63 KB) | DOI: 10.15850/ijihs.v3n2.582

Abstract

Objective: The objective of this study is to examine the relation between nutrition and brain memory. Qualified human resource is the most valuable national asset. Adequate nutrition and regular exercise provide higher achievement to create healthy and smart generations.Methods: The method applied in this study was experimental laboratory. This study was conducted on Juni 2011–Juli 2012 at the Biomedical and Biochemistry laboratory, Faculty of Medicine, Universitas Padjadjaran. The subjects were 8 weeks approximately 200–250 grams, male Wistar rats. The examination involved 56 male Wistar rats divided into 8 groups with different treatments. The groups which received exercise treatment were also given Glycine max and Phyllanthus niruri intakes. Results: NR2B gene expression changes can be described as the following results: (1) without practicing exercise (3,8) and after exercises (4,6); (2) Glycine max intake minus exercise (2,86) and Glycine max intake and exercises (3,17); (3) Phyllanthus niruri intake minus exercises (4,7) and Phyllanthus niruri intake and exercises (4,9); and (4) Glycine max and Phyllanthus niruri composition intake minus exercises (3,14) and Glycine max and Phyllanthus niruri composition intake and exercises (4,83).Conclusions: This study determines that exercises and Phyllanthus niruri intake enhance NR2B gene expressions. Glycine max inhibits the NR2B gene expressions. Glycine max and Phyllanthus niruri composition intake and either with or without practicing exercises enhance NR2B gene expressions. Therefore, practicing exercises and Phyllanthus niruri intake might cause brain cell apoptosis while Glycine max intake inhibits brain cell apoptosis. Keywords: Exercise, gene expressions, Glycin max, NR2B, Phyllanthus niruri DOI: 10.15850/ijihs.v3n2.582
Score for Neonatal Acute Physiology Perinatal Extension II (SNAPPE II) as the predictor of neonatal mortality hospitalized in neonatal intensive care unit James Thimoty; Dany Hilmanto; Tetty Yuniati
Paediatrica Indonesiana Vol 49 No 3 (2009): May 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (132.045 KB) | DOI: 10.14238/pi49.3.2009.155-9

Abstract

Background The assesment of severity of illness with scoringsystem has been used to predict neonatal mortality in neonatalintensive care unit (NICU). Score for Neonatal Acute PhysiologyPerinatal Extension II (SNAPPE II) is the best scoring systemalthough most of the studies were commonly conducted indeveloped countries.Objective To evaluate SNAPPE II as the predictor of neonatalmortality in NICU Hasan Sadikin General Hospital (HSGH)Ban dung.Methods This was a longitudinal observational study. All neonateshospitalized in NICU HSGH during the period of August toNovember 2008 were investigated according to SNAPPE IIrequirements. We excluded subjects admitted more than 48hours of age, who were discharged or moved to intermediatenewborn care ward less than 24 hours after admission. Predictionof mortality and determination of SNAPPE II cut-off point wereanalyzed using logistic regression. Discrimination was analyzedusing receiver operating characteristic (ROC) and calibration wasanalyzed using Hosmer-Lemeshow goodness-of-fit.Results Forty subjects fulfilled the inclusion criteria. There was agood relation between SNAPPE II and mortality prediction (P =0.007). The cut-off point for predicting mortality was 51. SNAPPEII showed good discrimination with AUC 0.933 (95% CI 0.843to 1.0) and good calibration 1.69 (P = 0.97).Conclusion SNAPPE II can be used to predict neonatal mortalityin NICU similar to that found in developed countries.
Co-Authors Dany Hilmanto Diah Dhianawaty James Thimoty Leonardo Lubis Muhamad Nurhalim Shahib Nurain Yahya Vita Muniarti Tarawan