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EFEK JUS BAWANG BOMBAY (ALLIUM CEPA LINN.) TERHADAP MOTILITAS SPERMATOZOA MENCIT YANG DIINDUKSI STREPTOZOTOCIN (STZ) Annisa Hasanah
Saintika Medika Vol. 11 No. 2 (2015): Desember 2015
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.v11i2.4203

Abstract

Diabetes melitus adalah penyakit metabolik yang ditandai dengan hiperglikemia. Sekitar 90% pria penderita DMmengalami penurunan kualitas spermatozoa. STZ  merupakan bahan toksik yang merusak sel β pankreas. Kandungan quercetin yang tinggi dalam bawang bombay (Allium cepa Linn.) melindungi spermatozoa dari kerusakan. Penelitian ini adalah penelitian eksperimental dengan rancangan posttest only control group design. Besar sampel menggunakan rumus Federer dengan jumlah sampel 32 ekor mencit yang dibagi empat kelompok perlakuan : K0 adalah kelompok kontrol diberi placebo dan jus bawang bombay 1 g/kgBB, K1 adalah kelompok kontrol DM yang diinduksi STZ dosis rendah 50 mg/ kgBB, K2 adalah kelompok induksi STZ dosis rendah dan jus bawang bombay 0,5 g/kgBB, K3 adalah kelompok induksi STZ dosis rendah dan jus bawang bombay 1 g/kgBB. Kualitas spermatozoa yang diperiksa adalah motilitas spermatozoa. Data dianalisis dengan uji Kruskal-Wallis dilanjutkan uji Mann-Whitney. Uji normalitas dengan Saphiro-Wilk didapatkan p<0,05 pada semua parameter (data tidak berdistribusi normal). Hasil uji Kruskal-Wallis didapatkan p<0,05, menunjukkan ada perbedaan signifikan motilitas pada keempat kelompok perlakuan. Uji Mann-Whitney menunjukkan perbedaan signifikan motilitas antar kelompok (p<0,05). Kesimpulan penelitian ini adalah pemberian jus bawang bombay dosis 0,5 g/kgBB dan 1 g/kgBB meningkatkan motilitas spermatozoa mencit yang dijadikan DM dengan induksi STZ.Kata Kunci : Jus bawang bombay (Allium cepa Linn.), motilitas spermatozoa, mencit (Mus musculus), streptozotocin (STZ)
PENGARUH EKSTRAK BIJI ANGGUR (VITIS VINIFERA) VAR ALPHONSO LAVALLEE TERHADAP FUNGSI GINJAL MENCIT JANTAN (MUS MUSCULUS) MODEL HIPERURISEMIA Mira Wiji Lestari; dr Isbandiah; Annisa Hasanah
Saintika Medika Vol. 13 No. 1 (2017): JUNI 2017
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.v13i1.5447

Abstract

Pengaruh Ekstrak Biji Anggur (Vitis vinivera) var Alphonso lavallee Terhadap Fungsi Ginjal Mencit Jantan (Mus musculus) Model Hiperurisemia.Latar Belakang : Prevalensi hiperurisemia di Indonesia sebesar 18% populasi. Hiperurisemia dapat menyebabkan terjadinya disfungsi ginjal.Kreatinin merupakan salah satu parameter untuk mengukur fungsi ginjal.Terjadinya disfungsi ginjal dapat dicegah menggunakan biji anggur var Alphonso lavallee.Biji anggur ini memiliki kandungan polifenol tinggi terutama proanthocyanidin, flavonoid, dan resveratrol yang berfungsi sebagai antiinflamasi, antioksidan, inhibisi COX-2, dan meningkatkan produksi NO.Tujuan:Mengetahui pengaruh ekstrak biji anggur var Alphonso lavallee terhadap fungsi ginjal mencit jantan (Mus musculus) model hiperurisemia.Metode : Eksperimental, The Post Test Only Control Group Design. Sampel terdiri dari 30 ekor mencit jantan yang dibagi menjadi 5 kelompok diantaranya kelompok kontrol -, kontrol + , dam 3 kelompok perlakuan. Semua kelompok kecuali kontrol – diinduksi dengan kalium oksonat 250 mg/kg/hari dan 3 kelompok perlakuan diberi ekstrak biji anggur var Alphonso lavallee dengan dosis 3.5 mg/ekor mencit/hari, 7 mg/ekor mencit/hari, dan 14 mg/ekor mencit/hari peroral selama 7 hari. Kreatinin serum diukur menggunakan spektrofotometer untuk menilai fungsi ginjal mencit.Analisis data menggunakan uji One way ANOVA, post hoc bonferroni, dan uji regresi.Hasil Penelitian : Ekstrak biji anggur var Alphonso lavallee dapat menurunkan kadar kreatinin serum secara signifikan dengan p < 0.001 pada dosis mulai dari 7 mg/ekor mencit/hari.Kesimpulan : Ekstrak biji anggur var Alphonso lavallee berpengaruh dalam mencegah terjadinya kerusakan fungsi ginjal pada mencit hiperurisemia. Kata kunci : Biji anggur var Alphonso lavallee, polifenol, fungsi ginjal, kalium oksonat
Pengaruh Pola Hidup Masyarakat terhadap Penyakit Diabetes Melitus di Desa Tengah Kecamatan Pantai Labu Yusril Iza Mahendra; Yunia Humairah Ayub; Bintang Rizki Angeli; Suhaila Syahda; Annisa Hasanah; Wahyudi Wahyudi
Jurnal Ilmiah Universitas Batanghari Jambi Vol 23, No 2 (2023): Juli
Publisher : Universitas Batanghari Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33087/jiubj.v23i2.2971

Abstract

Diabetes Mellitus (DM) is a chronic disease caused by a disturbance in the body, so that the body cannot produce or use blood glucose into the body's cells, resulting in glucose accumulating in the blood. Symptoms of diabetes are characterized by increased blood sugar which tends to be higher than normal. This study used quantitative research with cross sectional analysis method because this research was carried out at one time. The sample in this study was the elderly community in Tengah Village, Pantai Labu District, totaling 40 people. From the results of the research conducted, it shows that the residents or people in Tengah Village always adopt a healthy lifestyle, even the elderly. Because, we can see that researchers examined the community as many as 40 people. However, out of the 40 respondents, only 6 people had diabetes mellitus.
Hubungan Antara Durasi dan Frekuensi Paparan Layar Media Elektronik (screen time) dengan Perkembangan Bahasa pada Balita di Puskesmas Kendal Kerep di Kota Malang Annisa Hasanah; Nadia Paramita Bhakti Putri; Iwan Sis Indrawanto; Rahayu
Teaching and Learning Journal of Mandalika (Teacher) e- ISSN 2721-9666 Vol. 6 No. 1 (2025)
Publisher : Institut Penelitian dan Pengembangan Mandalika Indonesia (IP2MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/teacher.v6i1.2988

Abstract

The incidence of speech and language delay disorders in children in Indonesia ranges from 2.3-24.6%. The American Academy of Pediatrics (AAP) recommends that electronic media screen exposure should not be given to children under 18 months of age. While at the age of 2 to 4 years, exposure to electronic media screens is suggested to be limited to about 1 hour per day. The influence of the duration of the digital devices in electronic media screen exposure (screen time) greatly impacts language development. This study aims to determine the correlation between duration and frequency of exposure to screen time on language development of toddlers at Kendalkerep health center in Malang city. This study used a cross-sectional method with questionnaires and KPSP measuring instruments to determine language development in toddlers at Kendalkerep Health Center in Malang City. There was a correlation between duration and frequency of exposure to screen time on language development of toddlers at Puskesmas Kendalkerep in Malang City with a spearman correlation of duration and language development of r=0.375 (Moderate), while the spearman correlation of frequency and language development was r=0.424 (Moderate). The study concluded that there was a correlation between duration and frequency of exposure to Electronic Screen Time on language development of toddlers at Puskesmas Kendalkerep in Malang City.
Babuta'an Traditional Games In Increasing Students' Learning Motivation Annisa Hasanah; Zain Ahmad Fauzi; Fahri Fajrul Falah; Norma Paulina; Asyfa Nabila; Linda Rosydah
International Journal of Multilingual Education and Applied Linguistics Vol. 1 No. 2 (2024): May: International Journal of Multilingual Education and Applied Linguistics
Publisher : Asosiasi Periset Bahasa Sastra Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/ijmeal.v1i2.54

Abstract

The researcher chose the traditional game Bubuta'an to overcome noise outside the classroom due to school renovations which resulted in students' lack of focus on learning. The traditional game Bubuta'an is also a traditional game in South Kalimantan which in Indonesian is known as the game Si Buta-Si Buta. The aim of the research is to analyze the role of traditional babuta'an games in increasing students' learning motivation. The type of research used is Classroom Action Research with a qualitative approach. The research results show that the percentage of students' classical learning motivation obtained at the first meeting was 75% with the criterion "Mostly Skilled", at the second meeting it had increased to and had increased at the second meeting to 92% with the criterion " Almost All Skilled" and at the third meeting it had increased to 96% with the criteria "Almost All are Skilled" . This was because at the first meeting several students had not achieved the assessment indicators. So these conditions are below standards set by researchers for developing students' learning motivation. To overcome these obstacles, educators make improvements motivating, providing reinforcement, paying attention and reminding students to be more interested in participating in the learning process. The conclusions obtained by traditional game Babuta'an can be used as a means of developing students' learning motivation.
Improving Critical Thinking Skills and Collaboration Skills Using Problem Based Learning Models, DNGM Models, Wordwall Media and Dragon Games Fahri Fajrul Falah; Zain Ahmad Fauzi; Annisa Hasanah; Norma Paulina; Asyfa Nabila; Linda Rosydah
International Journal of Multilingual Education and Applied Linguistics Vol. 1 No. 3 (2024): August : International Journal of Multilingual Education and Applied Linguistic
Publisher : Asosiasi Periset Bahasa Sastra Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/ijmeal.v1i3.73

Abstract

The problem of this research is that there is still a lack of student activity in participatory learning as well as interaction and collaboration between students in group learning activities. In this research, Classroom Action Research (PTK) was carried out in three meetings. The subjects of this research were 25 class V students of SDN Antasan Besar 7 Banjarmasin. The measure of research success with learning completeness is that 80% of students achieved a KKM score above 80. The results of this research show that at Meeting I to Meeting III there was an increase in the acquisition of learning activities in the application of the learning model, resulting in the "Very Active" criteria at Meeting I, II and III. At Meetings II and III, learning activities increased to almost all very active. Students' critical thinking skills increased to almost all highly skilled at Meetings II and III. At Meetings II and III, students' collaboration skills increased to Almost All Skilled. Meanwhile, completeness of learning outcomes increased again to 100% at Meeting III. From the results of this research, it can be concluded that educators' activities experienced a very significant increase when implementing the PBL model supported by DNGM using Wordwall media and the Dragon Snake game, as well as student activities, critical thinking skills, collaboration skills, and learning outcomes.