wibowo, subur
Master Program Of Biomedic, Medical Faculty, UNISSULA, Semarang

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DIFFERENCE IN THE LEVELS OF FERRITIN, HEMOGLOBIN, AND ERYTHROCYTE COUNT OF STAGE 5 CHRONIC KIDNEY DISEASE PATIENTS AFTER ONE, THREE AND SIX MONTHS OF HEMODIALYSIS Wibowo, Subur; Chasani, Shofa; Wibowo, Joko Wahyu; Nasihun, Taufiqurrachman
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 10, No 1 (2019): June 2019
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (722.769 KB)

Abstract

INTRODUCTION: 77,892 chronic kidney disease patients in Indonesia undergo hemodialysis in 2017. However, the effects of period of undergoing hemodialysis on hemoglobin level, erythrocyte count, and ferritin level are still unclear.OBJECTIVE: This research aims at examining the effects of period of undergoing hemodialysis on the levels of ferritin, hemoglobin, and erythrocyte count of stage 5 of chronic kidney disease patients.METHODS: In the analytical observational research with a cross sectional design, 30 men meet the inclusion criteria and are randomly divided into 3 groups: one month group (1M-G), three months group (3M-G), and six months group (6M-G). Each of the research objects has undergone hemodialysis for one, three and six months. The levels of ferritin, hemoglobin, and erythrocyte count are analyzed with an immunoflourescence method.RESULTS: The Post Hoc LSD analysis states that the ferritin levels of 3M-G (718±63.61) and 6M-G (947±66.22) are significantly higher than that of 1M-G (383.77), p< 0.01. The ferritin level of 6M-G is significantly higher than that of 3M-G, p<0.01. The hemoglobin levels and erythrocyte counts between 1M-G (9.45±0.84) & (3.26±0.55), 3M-G (9.10±1.22) & (3.21±0.50) and 6M-G (8.35±1.21) & (2.92±0.40) are insignificant, p>0.05.CONCLUSION: After undergoing hemodialysis for three and six months, the ferritin levels improve significantly compared to that of one month of hemodialysis, and there is no significant difference in hemoglobin levels and erythrocyte counts.
An Overview of Erithocyt Index among Stroke Patients In Kraton Regional Hospital, Pekalongan Wibowo, Subur; Agustina Lestari, Anggun
INDOGENIUS Vol 4 No 3 (2025): INDOGENIUS
Publisher : Department of Publication of Inspirasi Elburhani Foundation Desa. Pamokolan, Kecamatan Cihaurbeuti, Kabupaten Ciamis, Provinsi Jawa Barat, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/igj.v4i3.622

Abstract

Background & Objective: Stroke is a serious health condition that requires immediate treatment. It occurs when blood supply to the brain is interrupted due to blockage or rupture of blood vessels in the brain, resulting in cell death in certain areas of the brain. This study aims to determine the erythrocyte indices (MCV, MCH, MCHC) in stroke patients. Method: The study design was descriptive, with a sample size of 24 participants. Total sampling was used for sample selection. The study was conducted at the inpatient ward of Kraton District General Hospital, Pekalongan Regency, from January to February 2025. Data analysis was performed using descriptive and analytical methods, presented in tables and narrated. Result: The study results showed that MCV levels were normal (80.00 μL/mL – 100.00 μL/mL) in all 24 samples (100%), with an average value of 85.32 μL/mL.  The majority of MCH levels showed normal results (27.00 pg – 31.00 pg) in 18 samples (75%), 3 samples (12.5%) with low values, and 3 (12.5%) samples with high values, with an average value of 34.32 pg. The majority of MCHC levels showed normal results (30.00–35.00 g/dL) in 15 samples (62.5%), 9 samples had high values, and there were no low results, with an average value of 29.2 g/dL. Conclusion: The conclusion of this study is that the average results of MCV, MCH, and MCHC in the respondents were normal.
Overview of Routine Blood Tests for Typhoid Fever Patients at Bendan Regional General Hospital, Pekalongan City Mahfudloh, Devi Syakirotul; Wibowo, Subur
INDOGENIUS Vol 4 No 3 (2025): INDOGENIUS
Publisher : Department of Publication of Inspirasi Elburhani Foundation Desa. Pamokolan, Kecamatan Cihaurbeuti, Kabupaten Ciamis, Provinsi Jawa Barat, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/igj.v4i3.624

Abstract

Background & Objective: Typhoid fever is an acute infectious disease that remains a health problem in Indonesia due to its high morbidity and mortality rates. This disease is caused by Salmonella typhi or Salmonella paratyphi and can be diagnosed through routine blood tests. This study aims to determine the routine blood profile of typhoid fever patients at Bendan Regional General Hospital in Pekalongan City. Method: This study used a descriptive design with a sample of 30 patients. Routine blood tests were performed using an automatic hematology analyzer. Results: The results showed that 18 samples (60%) had normal leukocyte counts, 6 samples (20%) had high leukocyte counts, and 6 samples (20%) had low leukocyte counts. For monocytes, 22 samples (73.34%) were within normal levels, 7 samples (23.33%) showed high levels, and 1 sample (3.33%) showed low levels. Conclusion: In general, routine blood tests showing white blood cell and monocyte counts in samples from typhoid fever patients at Bendan Regional General Hospital in Pekalongan City were within normal limits.
Overview of Hemoglobin and Hematocrit Levels in Stunted Toddlers in the Kajen 1 Community Health Center Working Area Hidayah, Laela Nurul; Wibowo, Subur
INDOGENIUS Vol 4 No 3 (2025): INDOGENIUS
Publisher : Department of Publication of Inspirasi Elburhani Foundation Desa. Pamokolan, Kecamatan Cihaurbeuti, Kabupaten Ciamis, Provinsi Jawa Barat, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/igj.v4i3.626

Abstract

Background & Objectives: Stunting is a condition in which a child's growth and development are disrupted due to prolonged malnutrition. Children who experience stunting are 2.7 times more likely to develop anemia. Common characteristics of anemia include decreased hemoglobin levels and decreased hematocrit (Ht) values. Malnutrition accompanied by anemia can lead to growth disorders, reduced cognitive and psychomotor function, and decreased immunity in children. This study aims to determine the hemoglobin and hematocrit levels in stunted toddlers in the working area of the Kajen 1 Community Health Center. Method: The type of research used was descriptive research, with sampling conducted using total purposive sampling. From a population of 27 toddlers, 18 samples of toddlers who met the inclusion and exclusion criteria were taken. Result: The results of hemoglobin level tests using the POCT method and hematocrit tests using the microhematocrit method showed hemoglobin levels above 11.0 g/dl in 100% of cases, normal hematocrit levels in 10 toddlers (56%), and low hematocrit levels in 8 toddlers (44%). with the lowest hematocrit level being 31% and the highest being 39%. Conclusion: Hemoglobin levels in stunted toddlers in the Kajen 1 Community Health Center working area were all normal above 11.0 g/dl, hematocrit levels were normal in 10 toddlers, and hematocrit levels were low in 8 toddlers.
Blood Type Profile in Relation to the Prevalence of Metabolic Diseases and Diabetes Mellitus at Kraton Regional General Hospital, Pekalongan Regency Wibowo, Subur; Safanah, Asti
INDOGENIUS Vol 4 No 3 (2025): INDOGENIUS
Publisher : Department of Publication of Inspirasi Elburhani Foundation Desa. Pamokolan, Kecamatan Cihaurbeuti, Kabupaten Ciamis, Provinsi Jawa Barat, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/igj.v4i3.629

Abstract

Background & Objective: Diabetes mellitus is one of the chronic metabolic diseases whose prevalence continues to increase in Indonesia and is the third leading cause of death in the country. The main disorder in diabetes is carbohydrate metabolism, which causes chronic hyperglycemia and poses a risk of complications in various organs of the body, such as the eyes, kidneys, nerves, heart, and blood vessels. In addition to genetic factors and lifestyle, several studies have shown an association between ABO blood type and the tendency to develop type 2 diabetes mellitus. This study aims to determine the distribution of blood types in relation to the tendency for metabolic diabetes mellitus at Kraton District General Hospital in Pekalongan. Method: This study used a descriptive design with 35 samples collected through total sampling among diabetes mellitus patients at Kraton District General Hospital in Pekalongan. Blood type testing was conducted using the slide method. Result: The results showed that blood type B had the highest percentage (40%), followed by blood type A (28.57%), blood type O (20%), and blood type AB (11.43%). Conclusion: It can be concluded that blood type B has a high percentage (40%) compared to other blood types. This indicates that blood type B is more dominant among diabetes mellitus patients in the sample at Kraton District General Hospital, Pekalongan.
Overview of Erythrocyte Index Values in Pregnant Women with Anemia at Kraton Regional General Hospital, Pekalongan Regency Rohali, Amelia; Wibowo, Subur
INDOGENIUS Vol 4 No 3 (2025): INDOGENIUS
Publisher : Department of Publication of Inspirasi Elburhani Foundation Desa. Pamokolan, Kecamatan Cihaurbeuti, Kabupaten Ciamis, Provinsi Jawa Barat, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/igj.v4i3.637

Abstract

Background & Objective: The erythrocyte index is the average value or corpuscular value. The erythrocyte index value includes the average erythrocyte volume obtained from the MCV value. The average hemoglobin content in erythrocytes can be seen from the MCH, while the average hemoglobin concentration in erythrocytes is determined by the MCHC value. The erythrocyte index in pregnant women with anemia shows a decrease in MCV during the early stages of iron deficiency. The severity of anemia increases if the Mean Corpuscular Hemoglobin Concentration (MCHC) also decreases. This study aims to determine the profile of erythrocyte indices in pregnant women with anemia. Method: This study is a descriptive studyusing total sampling with 30 respondents. Result: The study obtained 17 erythrocyte index values with a percentage (56.67%) indicating hypochromic microcytic anemia, and 13 erythrocyte index values with a percentage of (43.33%) indicating normochromic normocytic anemia. Conclusion: The results of the study on erythrocyte index profiles in pregnant women with anemia at Kraton General Hospital, Pekalongan Regency, revealed 17 samples (56.67%) with hypochromic microcytic anemia, meaning the erythrocytes are small in size and pale in color. Additionally, 13 samples (43.33%) were found to have normochromic normocytic anemia, meaning they have normal size and color.
Profile of Erythrocyte Index Values in Patients with Pulmonary Tuberculosis at Bendan Regional Hospital, Pekalongan City Qomariyah, Ismi Tri; Wibowo, Subur
INDOGENIUS Vol 4 No 3 (2025): INDOGENIUS
Publisher : Department of Publication of Inspirasi Elburhani Foundation Desa. Pamokolan, Kecamatan Cihaurbeuti, Kabupaten Ciamis, Provinsi Jawa Barat, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/igj.v4i3.638

Abstract

Background & Objective: Pulmonary tuberculosis (commonly known as TB) is an infectious disease caused by Mycobacterium tuberculosis. If not treated properly, this disease has the potential to cause various serious complications, even death. The objective of this study was to describe the erythrocyte index values in patients with pulmonary tuberculosis at Bendan Regional Hospital, Pekalongan City. Method: This research used a descriptive approach involving 30 samples. Examination of erythrocyte indices was carried out using an automatic analyzer method. Result: The results showed that 13 samples (43%) had microcytic hypochromic anemia, 9 samples (30%) had normocytic normochromic anemia, 5 samples (17%) had microcytic normochromic anemia, and 3 samples (10%) had normocytic hypochromic anemia. Conclusion: Overall, the most common type of anemia found in TB patients at Bendan Regional Hospital, Pekalongan City was microcytic hypochromic anemia.
Description of Erythrocyte Index Values in Chronic Kidney Disease Patients at Bendan Hospital, Pekalongan City Fadhila, Arina; Wibowo, Subur
INDOGENIUS Vol 4 No 3 (2025): INDOGENIUS
Publisher : Department of Publication of Inspirasi Elburhani Foundation Desa. Pamokolan, Kecamatan Cihaurbeuti, Kabupaten Ciamis, Provinsi Jawa Barat, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/igj.v4i3.653

Abstract

Background & Objective: Chronic Kidney Disease (CKD) is a condition characterized by the gradual and permanent decline of kidney function, which can lead to various complications, including anemia. Anemia in CKD patients is generally caused by reduced production of the hormone erythropoietin, iron deficiency, and the shortened lifespan of red blood cells due to the hemodialysis process. Erythrocyte index parameters, such as MCV, MCH, and MCHC, play a crucial role in determining the type of anemia in CKD patients. Method: This study used a descriptive design with a quantitative approach. The sample consisted of 30 CKD patients undergoing hemodialysis, selected using total sampling technique. Erythrocyte indices were examined automatically using a hematology analyzer. The data were analyzed and presented in the form of a frequency distribution table. Result: The examination results showed that the most dominant type of anemia was normochromic normocytic anemia (47%), followed by hypochromic microcytic anemia (37%), normochromic microcytic anemia (10%), and hypochromic normocytic anemia (6%). The average patient hemoglobin level was 8.4 g/dL and the average erythrocyte count was 2.7 million/µL Conclusion: The majority of CKD patients at Bendan Hospital, Pekalongan City, experience normochromic normocytic anemia. This finding highlights the importance of regular monitoring of erythrocyte indices to support the diagnosis and management of anemia in CKD patients.
Comparison of Hemoglobin Levels in Mothers Before and After Cesarean Section at Bendan Hospital, Pekalongan City Oktafiani, Aisah Fani; Wibowo, Subur
INDOGENIUS Vol 4 No 3 (2025): INDOGENIUS
Publisher : Department of Publication of Inspirasi Elburhani Foundation Desa. Pamokolan, Kecamatan Cihaurbeuti, Kabupaten Ciamis, Provinsi Jawa Barat, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/igj.v4i3.659

Abstract

Background & Objective: Cesarean section, or Sectio Caesarea, is a frequently used delivery method when vaginal birth is not possible or poses a risk to the mother and baby. Method: The type of research conducted was comparative research, which aims to compare the hemoglobin levels in pregnant women before and after undergoing a cesarean section at Bendan Hospital. Hemoglobin level is a very important indicator for assessing maternal health status, particularly during and after the delivery process. Result: The average hemoglobin level before cesarean delivery was known to be 11.7 g/dl, with a minimum level of 9.1 g/dl and a maximum level of 14.8 g/dl. Furthermore, the average hemoglobin level in pregnant women after cesarean delivery was 10.8 g/dl, with a minimum level of 7.7 g/dl and a maximum level of 13.2 g/dl. Conclusion: Based on the parametric test (paired test), a sig value of 0.000 < 0.05 was obtained, meaning there is a statistically significant difference between the hemoglobin levels in pregnant women before and after delivering by cesarean section at Bendan Hospital.