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All Journal Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Ilmu Multidisplin Journal of Clinical Pharmacy and Pharmaceutical Science Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Fef Rukminingsih
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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PENGUKURAN TEKANAN DARAH PADA PASIEN PESERTA JKN DENGAN PENYAKIT JANTUNG ISKEMIK DI INSTALASI RAWAT JALAN RUMAH SAKIT ST. ELISABETH SEMARANG Fef Rukminingsih; Nike Kusuma Dewi
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.619

Abstract

Ischemic heart disease (IHD) is defined as a lack of oxygen and decreased or absent blood flow to the myocardium caused by narrowing of the coronary arteries. Hypertension is a risk factor that plays an important role in IHD. Hypertension therapy in IHD patients aims to prevent death, myocardial infarction. This study aims to evaluate the achievement of blood pressure targets in IHD patients participating in JKN in the outpatient installation of St. Elisabeth Hospital Semarang. This research is a descriptive observational study using retrospective data. Data obtained from the medical records. The inclusion criteria were JKN participant patients with IHD in the Outpatient Installation of St. Elisabeth Hospital Semarang for the period of October-December 2019 who received antihypertensive, aged 26-65 years, had blood pressure data for two consecutive months. The results were 88 patients, consisting of 64 (72.73%) male patients, 46 (52.27%) patients aged 56-65 years. 57 (64.78%) patients had comorbidities, the most comorbidities were type 2 diabetes. The most widely used antihypertensive agents were beta blockers. A total of 82 (93.18%) patients reached the target blood pressure based on JNC 8. The greater the success in achieving the therapeutic target, the risk of death from IHD will decrease.
PENGGUNAAN INSULIN PADA PASIEN DIABETES MELITUS TIPE 2 PESERTA JKN DI INSTALASI FARMASI RAWAT JALAN RUMAH SAKIT ST. ELISABETH SEMARANG Fef Rukminingsih; Valentina Catur Nova
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 1 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (169.72 KB) | DOI: 10.36387/jiis.v6i1.611

Abstract

Diabetes mellitus (DM) type 2 is a chronic and progressive clinical syndrome, characterized by polyuria, polydipsi and polyphagy accompanied by increased blood glucose or hyperglycemia. Management of type 2 diabetes mellitus in patients with HbA1C values > 9% is by administering insulin or a combination of insulin with oral hypoglycemic agents. This study aims to determine the suitability of the type and dose of insulin in type 2 DM patients in the Outpatient Pharmacy Installation of St. Elisabeth Hospital Semarang. This research is a descriptive observational study using retrospective data. The data were obtained from the medical records of Universal Health Coverage participant patients with type 2 diabetes mellitus in the Outpatient Pharmacy Installation of St. Elisabeth Hospital Semarang, who only received insulin therapy in January 2020, is 26-65 years old, and has examination results for fasting blood glucose, post prandial blood glucose and HbA1C (examination results for the last 6 months). The results showed that 57 patients consisted of 29 (50.88%) male patients and 28 (49.12%) female patients. A total of 47 (82.46%) patients were more than 45 years old. A total of 38 patients (66.67%) received combination insulin and all patients had HbA1C values> 9%. The suitability of using insulin based on the type of insulin was 68.42% and most of the patients (80.70%) received inappropriate insulin doses.
Monitoring Tekanan Darah Pada Pasien Diabetes Melitus Tipe Dengan Hipertensi Di Puskesmas Tlogosari Kulon Kota Semarang Fef Rukminingsih; Putri Sri Wahyuni
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 2 No. 2 (2023): Oktober : Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v2i2.38

Abstract

Diabetes Mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia that occurs due to abnormalities in insulin secretion, insulin action, or both. DM is a risk factor for hypertension. Hypertension in DM increases the risk of complications so it is necessary to monitor whether blood pressure targets are achieved. This study aims to determine the achievement of blood pressure targets in type 2 DM patients with hypertension at the Tlogosari Kulon Health Center, Semarang City. This research is a descriptive observational study. Data collection uses purposive sampling technique. Data were obtained from medical records of type 2 DM patients with hypertension aged ≥ 45 years, who had blood pressure examination results on 2 consecutive visits in September 2022 – February 2023, use antihypertensives for at least 1 year. It was found 47 patients, consisting of 25 male patients and 22 female patients. A total of 26 patients were aged between 60-69 years. A total of 36 patients (76.59%) had taken antihypertensives for 1-5 years and 42 patients (89.40%) received single therapy, namely amlodipine. Only 1 patient received combination therapy of 2 drugs (amlodipine and candesartan). There were 14 patients who achieved the target blood pressure <140/90 mmHg (29.78%).
PENGUKURAN PERSEPSI TENAGA TEKNIS KEFARMASIAN DI KOTA DAN KABUPATEN SEMARANG TERHADAP APOTEK ONLINE Fef Rukminingsih; Azifatul Ula; Dian Safitri
Jurnal Ilmiah Manuntung Vol 8 No 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.636

Abstract

The development of online pharmacies in Indonesia will have an impact on the existence and role of Pharmaceutical Technicians. The number of pharmacies in Semarang City and Regency has reached almost 500 units. The number of Pharmaceutical Technicians who have practice permits in Semarang City is 477 people and in Semarang Regency is 115 people. Objective: This study aims to measure the perception of Pharmaceutical Technicians in Semarang City and Regency towards online pharmacies. Method: This research is a descriptive observational study using a cross sectional study design with using purposive sampling technique. The research data was obtained through a questionnaire in the form of a Likert scale which was distributed via google form in the Whatsapp group of Persatuan Ahli Farmasi Indonesia of Semarang City and Regency. Perceptions that are measured are drug guarantees, prices and consumer services. Pharmaceutical Technicians is said to have a positive perception of online pharmacies if the average score of the three parameters is in the range of 802.5 – 1284. Results: Respondents involved in this study were 321 respondents. Female respondents were 288 respondents (89.72%), 270 respondents (84.11%) aged less than 36 years and 177 respondents (55.14%) had Diploma III Pharmacy education. The drug guarantee parameter got a score of 1098, the drug price parameter got a score of 904 and the consumer service parameter got a score of 1035.5. The average score for the three parameters is 1012.5. Conclusion: Pharmaceutical Technicians in Semarang City and Regency have a positive perception toward online pharmacies.
KEPATUHAN MINUM OBAT PASIEN HIPERTENSI PESERTA JKN DI INSTALASI RAWAT JALAN RUMAH SAKIT SITI KHODIJAH KOTA PEKALONGAN Aqilatul Maziah; Fef Rukminingsih; Paulina Maya Octasari
Jurnal Ilmiah Manuntung Vol 10 No 1 (2024): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v10i1.741

Abstract

Hypertension is the highest case of non-communicable diseases (NCDs) in Pekalongan City. Uncontrolled hypertension can increase the risk of morbidity and mortality. Taking antihypertensive medication regularly can control the blood pressure of hypertensive patients so compliance with taking medication is the main factor that influences the success of therapy. This study aims to determine the medication compliance of hypertensive patients who are national health insurance participants at the Outpatient Installation of Siti Khodijah Hospital, Pekalongan City. This research is a descriptive observational study with a cross-sectional design. The sampling technique used is accidental sampling. Compliance was measured using the MMAS-8 (Morisky Medication Adherence Scale) questionnaire. Respondents were hypertensive patients in the outpatient installation of Siti Khodijah Hospital, Pekalongan City, aged ≥26 years, who were National Health Insurance participants and underwent examinations in March-April 2023. The data was analyzed qualitatively and quantitatively. The results revealed that of the 260 respondents consisting of 150 female patients and 110 male patients, most of the patients were ≥46 years old (91.92%), had an educational background of elementary school graduates (32.7%), high school (32.3%) and higher education (35%). A total of 67 respondents were housewives (25.77%) and 47 respondents did not work (18.07%). Meanwhile, others work in various professions such as teachers/lecturers, state civil servants, private employees and entrepreneurs. The adherence to taking medication for hypertensive patients at the Outpatient Installation of Siti Khodijah Hospital, Pekalongan City, was 82.31% compliant and 17.69% non-compliant. Patients aged ≥46 years were more compliant. Adherence to taking medication decreases as the duration of taking medication increases and the number of medications taken increases.
HIPERTENSI EMERGENSI DI INTENSIVE CARE UNIT (ICU) RUMAH SAKIT UMUM DAERAH (RSUD) TUGUREJO SEMARANG Setyoningrum Pujiastuti; Fef Rukminingsih
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 1 No. 1 (2022): April: Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v1i1.3

Abstract

A sudden increase in blood pressure reaching> 180/120 mmHg accompanied by involvement of organ damage is called hypertensive emergencies. Nationwide Emergency Department recorded visits of hypertensive emergency cases as much as 3309 million in 2006 and 6178 million in 2013. The Hospital data information system (SIMRS) in Tugurejo Regional Hospital Semarang in 2017 found that the number of patients diagnosed with hypertension reached 1,125 patients. The aim of this study was to evaluate the use of antihypertension in hypertensive emergency patients in the Intensive Care Unit (ICU) of Tugurejo Hospital Semarang in the period January - December 2018. This study is a descriptive observational study using retrospective data. Data retrieval was done by looking at the medical record data of patients with hypertensive emergencies who received hypertension therapy in the ICU Tugurejo Hospital in the period January - December 2018. Data were analyzed based on patient characteristics, antihypertensive use patterns and evaluation of antihypertensive use. The number of patients who fulfilled the inclusion and exclusion criteria were 58 patients. The results of this study indicate that the suitability of antihypertensive use in decreasing systolic blood pressure at 1 hour, 2 – 6 hours, 24 – 48 hours in a row is 81.03%; 24.14%; 20.93%. Whereas for a decrease in diastolic blood pressure at 1 hour, 2 – 6 hours, 24 – 48 hours respectively 77.59%; 43.10%; 74.42% according to the ACC / AHA guidelines (2018).     
Pengaruh Sistem Penyimpanan Sediaan Farmasi pada Karakteristik Fisik di Apotek Dataran Rendah dan Dataran Tinggi Bayu Kristianto, Yosua; Diyah Ikasari, Endang; Fef Rukminingsih
Jurnal Ilmu Multidisiplin Vol. 4 No. 1 (2025): Jurnal Ilmu Multidisplin (April–Mei 2025)
Publisher : Green Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38035/jim.v4i1.824

Abstract

Penyimpanan persediaan farmasi harus mengikuti regulasi yang berlaku untuk menjaga kualitas dan mencegah kerusakan. Tujuannya menjaga kualitas, mencegah penyalahgunaan, dan mengelola persediaan secara efisien. Apotek berperan penting dalam pengelolaan ini, mengingat faktor lokasi dan kondisi geografis seperti suhu dan kelembaban dapat mempengaruhi karakteristik fisik dari sediaan farmasi tersebut. Pengamatan sistem penyimpanan dilakukan secara deskriptif observasional sesuai dengan Petunjuk Teknis Standar Pelayanan Kefarmasian. Tujuan penelitian ini adalah mengevaluasi kesesuaian proses penyimpanan obat di apotek dataran rendah dan dataran tinngi dengan pedoman standar, mengidentifikasi faktor-faktor yang mempengaruhi kerusakan mutu sediaan farmasi, menganalisis pengaruh suhu, kelembaban, dan kondisi penyimpanan terhadap stabilitas fisika sediaan farmasi, serta perubahan stabilitas sediaan farmasi pada kondisi dan waktu tertentu di kedua apotek tersebut. Pengujian karakteristik fisik sediaan farmasi untuk mengevaluasi pengaruh sistem penyimpanan sediaan farmasi di dua apotek dengan kondisi geografis berbeda, melibatkan sampel sediaan farmasi padat, semi padat dan cair dengan zat aktif vitamin C. Pengujian karakteristik fisik sediaan farmasi dilakukan pada bulan ke nol sampai bulan ke tiga dengan menganalisis data uji sediaan farmasi SPSS versi 24. Hasil penelitian diperoleh karakteristik fisik sediaan farmasi baik pada sediaan padat, semipadat dan cair yang dilakukan pada apotek dataran rendah dan dataran tinggi memiliki hasil berpengaruh signifikan pada pengujian kerapuhan, kekerasan dan waktu hancur pada sediaan padat. Berpengaruh signifikan pada pengujian daya lekat, daya sebar, uji pH pada sediaan semipadat. Berpengaruh signifikan pada pengujian bobot jenis, uji pH, uji viskositas pada sediaan cair. Berdasarkan hasil tersebut sediaan farmasi yang disimpan pada apotek pada kondisi geografis yang berbeda di apotek mengalami perbedaan karakteristik fisik yang signifikan (p<0.05).
Co-Authors Aqilatul Maziah Azifatul Ula Bayu Kristianto, Yosua Dian Safitri Diyah Ikasari, Endang Nike Kusuma Dewi Paulina Maya Octasari Putri Sri Wahyuni Setyoningrum Pujiastuti Valentina Catur Nova