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All Journal Husada Mahakam: Jurnal Kesehatan Sains Medisina
Dini Indriaty Yusran
Poltekkes Kemenkes Kaltim
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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PENGARUH INDEK HEMOLISIS TERHADAP PENINGKATAN KADAR SERUM GLUTAMATE OXALOACETAT TRANSAMINASE (SGOT) Laila Ariyani; Loly R.D Siagian; Dini Indriaty Yusran
Husada Mahakam Vol 9 No 2 (2019): Nopember 2019
Publisher : Poltekkes Kemenkes Kalimantan Timur (URL: http://poltekkes-kaltim.ac.id/)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (204.536 KB) | DOI: 10.35963/hmjk.v5i1.169

Abstract

Serum Glutamate Oxaloacetat Transaminase (SGOT) adalah salah satu enzim aminotransferase yang berada di sel hati. Kadar SGOT dapat meningkat karena nekrosis sel-sel hati seperti sirosis tetapi dapat juga disebabkan karena ketidak-akuratan pada saat pra-analitik, salah satunya hemolisis. Hemolisis dapat menyebabkan peningkatan ketidak-akuratan pada pemeriksaan SGOT. Tujuan dari penelitian ini adalah untuk mengetahui indek hemolisis dan melihat adanya pengaruh indek hemolisis terhadap peningkatan kadar SGOT.Jenis penelitian ini adalah eksperimental. Sampel pada penelitian ini sebanyak 10 sampel. Masing-masing sampel dimasukkan kedalam 7 tabung, satu tabung tanpa hemolisat dan enam tabung lainnya ditambahkan hemolisat dengan indek hemolisis H1 sampai H6. Seluruh sampeln kemudian diperiksa kadar SGOT. Hasil penelitian ini diuji statistik dengan uji Kolmogorov Smirnov, kemudian dianalisa dengan menggunakan uji korelatif Pearson.Dari hasil penelitian ini didapatkan rata-rata indek hemolisis sebesar 1,55 mg/dl dan peningkatan kadar SGOT pada sampel yang ditambahkan indek hemolisis H1 sampai H6 berturut-turut yaitu 25,63 U/L; 28,96 U/L; 37,37 U/L; 64,88 U/L; 79,08 U/L; 109,45 U/L. Peningkatan kadar SGOT setelah ditambahkan enam indek hemolisis besar 4%, 7%, 16%, 43%, 58% dan 88 %.Dari penelitian ini dapat disimpulkan bahwa terdapat pengaruh indek hemolisis terhadap peningkatan kadar SGOT.
Analisis Cemaran Logam Berat Timbaldan Kadmium Pada Produk Kosmetika BB Cream Ganea Qorry Aina; Dini Indriaty Yusran; Tiara Dini Harlita; Puput Uswatun Hasanah; Muhammad Ivan Saputra
Sains Medisina Vol 1 No 3 (2023): Sains Medisina
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (310.958 KB)

Abstract

Blemish Balm Cream (BB Cream), is a cosmetic product that is often used by women. In the composition of BB Cream, there are basic ingredients, one of which is a coloring agent that has many contaminants such as lead and cadmium. Dyes such as CI. 77492 or called iron oxide already contains lead and cadmium with levels < 10 and < 5 ppm. Long-term exposure to lead and cadmium can cause kidney damage and impaired nerve function. The purpose of this study was to determine that the levels of lead and cadmium in BB Cream circulating in the Samarinda area had met the safe limit. This research is a descriptive study using Atomic Absorption Spectrophotometry method. The variables in this study are the independent variables, namely the levels of lead and cadmium in BB Cream circulating in the Samarinda area. The results of measuring the levels of lead and cadmium in 10 samples of BB Cream showed that the levels of lead and cadmium in the tested BB Cream did not exceed the contamination limit. Based on this research, it can be concluded that there are lead and cadmium content from 10 samples, and of these 10 samples all 100% contain lead and cadmium and meet the requirementsfor the standard lead contamination 10 ppm and standard cadmium 5 ppm.
Co-Authors Ganea Qorry Aina Laila Ariyani Loly R.D Siagian Muhammad Ivan Saputra Puput Uswatun Hasanah Tiara Dini Harlita