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All Journal Jurnal Teknosains Biology, Medicine, & Natural Product Chemistry Majalah Obat Tradisional Jurnal Farmasi Sains dan Komunitas PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Pharmaceutical Sciences and Research (PSR)
Andhi FAHRURROJI
Universitas Tanjungpura
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Economics, Econometrics & Finance Health Professions Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Mechanical Engineering Medicine & Pharmacology Public Health Social Sciences

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The Effect of Angkak Addition Towards DPPH Antioxidant Activity and Yields in Mixed Angkak-Red Ginger Extracts Christy, Clarissa; Nugraha, Fajar; Fahrurroji, Andhi; Anastasia, Desy Siska
Biology, Medicine, & Natural Product Chemistry Vol 14, No 1 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.141.73-82

Abstract

Angkak and red ginger, which represents West Borneo’s Chinese ethnic group’s herbal cooking, were studied to produce antioxidant activity through shogaol along with monacolin K and respond to DPPH (2, 2-diphenyl-1-picrylhydrazyl) test. This research aims to combine the two ingredients into extracts and observe how they affect the yields and IC50 value. Methods were started with the extraction of both materials in a variety of simplicia powder weights using 800 rpm stirring speed at 60°C for 120 minutes. The extracts were then tested for percentage yield (%), Thin Layer Chromatography (TLC), and half-maximal inhibitory concentration (IC50) value. IBM SPSS Statistics 25 analysis was also carried out at the end for yields and IC50 values data. Results showed that the angkak addition affected the IC50 value without giving any significant impact on each yield amount (p-value>0,05). Increased angkak in the variations led to the IC50 values decrease, ranging from 122.996 ppm (Mix 1) to 225.399 ppm (Mix 3). Angkak’s pigments and red ginger’s polyphenol compounds which provide antioxidant ability were found to occupy Mix extracts based on the TLC profile. In conclusion, angkak decreased the DPPH antioxidant activity of its extract combination with red ginger, but did not affect the yield percentage.
Co-Authors Amanda Angelina Sinaga, Amanda Angelina Anastasia, Desy Siska Anggraini, Dwi Willa Bambang WIJIANTO Christy, Clarissa Diana Susanti Emilia - Fajar Nugraha Juhardi, Jesslyn Felicia Liza Pratiwi Luliana, Sri Lumbantoruan, Ellya Catharine Romanna Aprilya Meilvina, Meilvina Missy, Felesia Mistika Zakiah Wintari Taurina Yuswar, Muhammad Akib