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All Journal Nexus Kedokteran Klinik Jurnal Prima Medika Sains
Aulia Nurul Fatimah
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Health Professions Medicine & Pharmacology Nursing Public Health

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Efek Anestesi Inhalasi Sevofluran dan Isofluran Terhadap Frekuensi Nadi Fatimah, Aulia Nurul; Sudjito, Mulyo Hadi; Probandari, Ari
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.044 KB)

Abstract

Background: Anesthesia is an important part of the surgery. Sevoflurane and isoflurane are two inhalation anesthesia drugs have been commonly used. During anesthesia, one of indicators should be monitored is frequency of pulse. This research aimed to know the effects of these two drugs to the frequency of pulse. Methods: This research was an analytical observational research with the approach of cross sectional. The sample was taken by consecutive sampling after being selected based on the inclusion and exclusion criteria. Totally, 50 patients were divided into two groups of inhalation anesthetic sevoflurane and inhalation anesthetic sevoflurane and isoflurane. Data was analyzed with independent t test. Results: The p values on t-independent test in the early phase of the pulse frequency, phase induction and phase intubation were 0.04; 0.00; 0.02, and of the phase 5’ of incision, 10’of incision and 15’of incision were 0.02; 0,0; 0.03. This results showed statistical significant of mean of pulse-frequency difference between sevoflurane and isoflurane in each of phase of inhalation anesthesia. Conclusions: Both sevoflurane and isoflurane influence the frequency of pulse. The mean of pulse frequency by isoflurane is higher than sevoflurane. However, inhalation anesthesia sevoflurane provides better stability than isoflurane. Keywords: Anesthetic Inhalation, Frequency of Pulse, Isoflurane, Sevoflurane
Efek Anestesi Inhalasi Sevofluran dan Isofluran Terhadap Frekuensi Nadi Aulia Nurul Fatimah; Mulyo Hadi Sudjito; Ari Probandari
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.044 KB)

Abstract

Background: Anesthesia is an important part of the surgery. Sevoflurane and isoflurane are two inhalation anesthesia drugs have been commonly used. During anesthesia, one of indicators should be monitored is frequency of pulse. This research aimed to know the effects of these two drugs to the frequency of pulse. Methods: This research was an analytical observational research with the approach of cross sectional. The sample was taken by consecutive sampling after being selected based on the inclusion and exclusion criteria. Totally, 50 patients were divided into two groups of inhalation anesthetic sevoflurane and inhalation anesthetic sevoflurane and isoflurane. Data was analyzed with independent t test. Results: The p values on t-independent test in the early phase of the pulse frequency, phase induction and phase intubation were 0.04; 0.00; 0.02, and of the phase 5 of incision, 10of incision and 15of incision were 0.02; 0,0; 0.03. This results showed statistical significant of mean of pulse-frequency difference between sevoflurane and isoflurane in each of phase of inhalation anesthesia. Conclusions: Both sevoflurane and isoflurane influence the frequency of pulse. The mean of pulse frequency by isoflurane is higher than sevoflurane. However, inhalation anesthesia sevoflurane provides better stability than isoflurane. Keywords: Anesthetic Inhalation, Frequency of Pulse, Isoflurane, Sevoflurane
The effectiveness of butterfly pea flower extract cream on collagen synthesis in post-dermapen wound healing Fatimah, Aulia Nurul; Hutabarat, Bartimeus Nicomama; Chairul, Muhammad
Jurnal Prima Medika Sains Vol. 6 No. 2 (2024): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v6i2.5744

Abstract

Skin wounds, whether acute or chronic, disrupt the integrity of the largest organ in the human body. The healing process involves intricate stages, with collagen playing a crucial role. Microneedling therapies, such as dermapen, stimulate collagen production and improve skin texture. This study investigated the effect of butterfly pea flower (Clitoria ternatea) extract cream on collagen production during the healing of dermapen-induced wounds in obese Wistar rats. Dermapen treatment, a minimally invasive cosmetic procedure, induces controlled skin punctures to stimulate collagen production. However, obesity can impair wound healing. This study aimed to determine if butterfly pea extract, rich in antioxidants, could enhance collagen synthesis and accelerate wound closure in obese rats. The results demonstrated that all treatment groups with butterfly pea extract cream exhibited significantly faster wound healing compared to the control group. Histopathological analysis revealed denser collagen deposition in the treatment groups, particularly those treated with 7% and 10% extract cream. These findings suggest that butterfly pea extract cream may have therapeutic potential in promoting efficient wound healing, particularly in obese individuals, by enhancing collagen production and accelerating the recovery process.
Co-Authors Ari Probandari Ari Probandari Chairul, Muhammad Hutabarat, Bartimeus Nicomama Mulyo Hadi Sudjito Mulyo Hadi Sudjito