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All Journal Jurnal Prima Medika Sains Buletin Kedokteran dan Kesehatan Prima
Hutabarat, Bartimeus Nicomama
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health

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The effectiveness of butterfly pea flower extract cream on collagen synthesis in post-dermapen wound healing Fatimah, Aulia Nurul; Hutabarat, Bartimeus Nicomama; Chairul, Muhammad
Jurnal Prima Medika Sains Vol. 6 No. 2 (2024): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v6i2.5744

Abstract

Skin wounds, whether acute or chronic, disrupt the integrity of the largest organ in the human body. The healing process involves intricate stages, with collagen playing a crucial role. Microneedling therapies, such as dermapen, stimulate collagen production and improve skin texture. This study investigated the effect of butterfly pea flower (Clitoria ternatea) extract cream on collagen production during the healing of dermapen-induced wounds in obese Wistar rats. Dermapen treatment, a minimally invasive cosmetic procedure, induces controlled skin punctures to stimulate collagen production. However, obesity can impair wound healing. This study aimed to determine if butterfly pea extract, rich in antioxidants, could enhance collagen synthesis and accelerate wound closure in obese rats. The results demonstrated that all treatment groups with butterfly pea extract cream exhibited significantly faster wound healing compared to the control group. Histopathological analysis revealed denser collagen deposition in the treatment groups, particularly those treated with 7% and 10% extract cream. These findings suggest that butterfly pea extract cream may have therapeutic potential in promoting efficient wound healing, particularly in obese individuals, by enhancing collagen production and accelerating the recovery process.
The effect of physical exercise on blood glucose levels in patients with type 2 diabetes mellitus Siregar, Annisa Surto; Ginting, Rapael; Putri, Nadya Nazimuddin; Leslie, William; Hutabarat, Bartimeus Nicomama; Syahputra, Ari Denggan
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6583

Abstract

Diabetes Mellitus (DM) is a chronic metabolic disease characterized by hyperglycemia. This study aimed to analyze the effect of physical exercise on blood glucose levels in patients with Type 2 DM at the Medan Johor Public Health Center. This analytical observational study utilized a case-control design and involved 34 respondents, divided into a case group (with uncontrolled blood glucose levels) and a control group (with controlled blood glucose levels). Data on physical activity, including frequency, duration, and intensity of exercise, were obtained through interviews using the GPAQ questionnaire, while blood glucose level data were sourced from medical records. The results showed a significant relationship between physical activity (p=0.028), frequency of physical exercise (p=0.006), duration of physical exercise (p=0.015), and intensity of physical exercise (p=0.034) with blood glucose levels. Physical exercise performed at least three times a week, for a minimum duration of 30 minutes per session, and at an appropriate intensity proved effective in controlling blood glucose levels in patients with Type 2 DM. This study emphasizes the importance of incorporating physical exercise into the management plan for Type 2 DM.
The effect of physical exercise on blood glucose levels in patients with type 2 diabetes mellitus Siregar, Annisa Surto; Ginting, Rapael; Leslie, William; Putri, Nadya Nazimuddin; Hutabarat, Bartimeus Nicomama; Syahputra, Ari Denggan
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6583

Abstract

Diabetes Mellitus (DM) is a chronic metabolic disease characterized by hyperglycemia. This study aimed to analyze the effect of physical exercise on blood glucose levels in patients with Type 2 DM at the Medan Johor Public Health Center. This analytical observational study utilized a case-control design and involved 34 respondents, divided into a case group (with uncontrolled blood glucose levels) and a control group (with controlled blood glucose levels). Data on physical activity, including frequency, duration, and intensity of exercise, were obtained through interviews using the GPAQ questionnaire, while blood glucose level data were sourced from medical records. The results showed a significant relationship between physical activity (p=0.028), frequency of physical exercise (p=0.006), duration of physical exercise (p=0.015), and intensity of physical exercise (p=0.034) with blood glucose levels. Physical exercise performed at least three times a week, for a minimum duration of 30 minutes per session, and at an appropriate intensity proved effective in controlling blood glucose levels in patients with Type 2 DM. This study emphasizes the importance of incorporating physical exercise into the management plan for Type 2 DM.
Co-Authors Aulia Nurul Fatimah Chairul, Muhammad Leslie, William Putri, Nadya Nazimuddin Rapael Ginting Siregar, Annisa Surto Syahputra, Ari Denggan