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All Journal As-syifaa Jurnal Farmasi
Eka Mega Asariningtyas
Fakultas Farmasi Universitas Muslim Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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EFEK ANTIINFLAMASI EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura L.) PADA MENCIT (Mus musculus) Safriani Rahman; Aulia Wati; Eka Mega Asariningtyas
As-Syifaa Jurnal Farmasi Vol 9, No 1 (2017): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (48.17 KB) | DOI: 10.33096/jifa.v9i1.244

Abstract

Leaf cherry (Muntingia Calabura L) empirically been used by the public as an anti-inflammatory drug. Cherry leaf contains flavonoids are thought to have antioxidant effects. This study has been tested antiinflammatory effect of ethanol extract of leaves of cherry (Muntingia Calabura L) in mice (Mus musculus). A total of 15 mice were divided into 5 groups of 3 animals. Group I (control) are given Na.CMC 1% w/v, Group II, III, and IV (treatment) were given cherry leaf extract ethanol concentration of 1% w / v, 3% w / v, and 5% w / v, as well as groups V (comparison) given Diclofenac Sodium 0.195 mg / 30 gBW. Before treatment all groups karagen induced with 1% w / v in intraplantar. Antiinflammatory effect was measured using pleytismometer. The results were analyzed statistically by one-way ANOVA method. The results showed that the ethanol extract of cherry leaf has anti-inflammatory effects and the concentration of 3% and 5% w / v has an effect no different to that diclofenac sodium.
Co-Authors Aulia Wati Safriani Rahman