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All Journal Jurnal Kebidanan Jurnal Penelitian Kesehatan Suara Forikes Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya
Abadiyah Zakiah Kustantina
Airlangga University
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Pengaruh Variasi Dosis Ekstrak Terong Belanda Terhadap Konsentrasi Spermatozoa Pada Mus Muscullus Yang Dipapar Timbal Asetat Abadiyah Zakiah; Reny I’tishom; Siti Khaerunnisa
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 11 (2020): Nomor Khusus Mei-Juni 2020
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf11nk319

Abstract

Infertility is a 10-15% problem experienced by men around the world. One of the causes of infertility in men is caused by an increase in reactive oxygen species (ROS) by toxic substances such as heavy metal lead (Pb). This research was conducted to find the potential of Dutch eggplant fruit (Solanum betaceum) in various doses to increase the concentration of mice spermatozoa (Mus muscullus) exposed to lead acetate. Dutch eggplant has a good phenolic content as an antioxidant to prevent free radicals. The study design used was Posttest only control group design with a sample of 40 male mice. The treatment time in all groups is 35 days. Mice were divided into 5 groups that were given oral treatment. The control group was given 75 mg/kgBW of lead acetate treatment. The treatment group was given lead acetate 75mg / KgBB and Dutch eggplant extract at various doses of 100 mg/kgBW (P1), 200 mg/kgBW (P2), and 400 mg/kgBW (P3). The results showed that Dutch eggplant extract (Solanum betaceum) with various doses could significantly increase spermatozoa concentration. The optimal dose of Dutch eggplant extract (Solanum betaceum) in mice exposed to lead is 100 mg/kg/day in the treatment group (P1). Keywords: tamarillo; spermatozoa concentration ABSTRAK Infertilitas merupakan masalah 10-15% yang dialami pria di seluruh dunia. salah satu penyebab infertilitas pada pria disebabkan oleh peningkatan reactive oxygen species (ROS) oleh bahan toksik seperti logam berat timbal (Pb). Penelitian ini dilakukan untuk menemukan potensi buah terong belanda (Solanum betaceum) dalam berbagai dosis terhadap peningkatan konsentrasi spermatozoa mencit (Mus musculus) yang dipapar timbal asetat. Terong belanda mempunyai kandungan fenolik yang baik sebagai antioksidan untuk mencegah radikal bebas. Desain penelitian yang digunakan Posttest only control group design dengan sampel 40 mencit jantan. Waktu perlakuan pada semua kelompok yaitu 35 hari. Mencit dibagi menjadi 5 kelompok yang diberikan perlakuan secara oral. Kelompok kontrol diberikan perlakuan timbal asetat 75mg/KgBB. Kelompok perlakuan diberikan timbal asetat 75mg/KgBB dan ekstrak terong belanda dengan berbagai dosis 100mg/KgBB (P1), 200mg/KgBB (P2), dan 400mg/KgBB (P3). Hasil penelitian menunjukkan bahwa ekstrak terong belanda (Solanum betaceum) dengan berbagai dosis mampu meningkatkan konsentrasi spermatozoa secara signifikan. Dosis optimal pemberian ekstrak terong belanda (Solanum betaceum) pada mencit yang dipapar timbal adalah 100 mg/kgBB/hari pada kelompok perlakuan (P1). Kata kunci: terong belanda; konsentrasi spermatozoa
Solanum betaceum Extract as a Protective on Spermatozoa Morphology of Mice Exposed to Lead Acetate Rima Wirenviona; Reny I'tishom; Siti Khaerunnisa; Anak Agung Istri Dalem Cinthya Riris; Nurul Fatimah Susanti; Nurul Jannatul Wahidah; Abadiyah Zakiah Kustantina
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 5, No 1 (2021)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v5i1.4594

Abstract

Environmental pollution is one of the factors that contribute to the decline in male fertility. Lead is one of six air pollutants harmful to the reproductive system. One parameter of infertility in men is an increase in reproductive function observed with decreased morphological abnormalities of spermatozoa. The purpose is to analyze the effect of giving various dosages of Solanum betaceum extract on spermatozoa morphology of mice exposed to lead acetate. This study was true experimental using a randomized post-test only control group design. The total sample was 40 male mice Balb/ C taken by simple random sampling technique. Treatment and maintenance of experimental animals for 35 days. Statistical tests showed there were significant differences with p-value 0.005. Solanum betaceum extract can be used as a protective to improve the normal morphology spermatozoa of mice that exposed to lead acetate.
Castration Punishment for Sex Offenders: Reproductive Health Science Review Anak Agung Istri Dalem Cinthya Riris; Rima Wirenviona; Abadiyah Zakiah Kustantina
Jurnal Kebidanan Vol 12, No 2 (2023): August 2023
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jk.12.2.2023.137-156

Abstract

Sexual crime is a form of crime in a society whose development is increasing based on their motives, traits, form, intensity, and modes. Women and children are subjected to victims of sexual crimes. The increase in sexual crimes caused the government to regulate castration punishment for sex offenders. Castration in health is surgery on the reproductive organs or using certain chemicals to reduce and eliminate sexual drive in men. The implementation of chemical castration in Indonesia is expected to have a deterrent effect on the perpetrators and prevent new cases of sexual violence. On the other hand, the implementation of chemical castration is thought to be against human rights. Related to the reproductive health perspective, castration as punishment can cause a decreasing reproductive function to come into sexual desire. Behavior aberration is a form of integrated multifactorial motives and the reason will not always biological factor or sexual drive. This article discusses the handling of sexual crimes that are comprehensively studied, especially in the area of reproductive health.
Co-Authors Anak Agung Istri Dalem Cinthya Riris Anak Agung Istri Dalem Cinthya Riris I'tishom, Reny Nurul Jannatul Wahidah Rima Wirenviona Rima Wirenviona Siti Khaerunnisa Susanti, Nurul Fatimah