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Ekstrak Solanum betaceum Mampu Meningkatkan Tebal Epitel dan Diameter Tubulus Seminiferus pada Mencit (Mus musculus) yang Terpapar Timbal Asetat Nurul Fatimah Susanti; Reny I’tishom; Siti Khaerunnisa
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 11 (2020): Nomor Khusus Mei-Juni 2020
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf11nk320

Abstract

One of the environmental factors that cause male infertility is heavy metal pollution such as lead. Lead can interfere with male fertility. Flavanoids are antioxidants that can prevent the negative effects caused by lead. The flavonoids contained in the Solanum betaceum extract have the potential to prevent the adverse effects of lead on the reproductive tract of mice because it can prevent oxidative stress. So it can affect the thickness of the seminiferous tubule epithelium and the diameter of the seminiferous tubules of mice exposed by lead acetat. The research method was a pure experimental laboratory (true experimental) randomized posttest only control group design approach. The total sample of 40 heads was divided into 5 groups. The study used 5 treatments. The concentration of Solanum betaceum for research group 100 mg/kg BW/day, 200 mg/kg BW/day, 400 mg/kg BW/day. Data analysis was performed analytically using One Way Anova. The results showed the mean ± standard deviation of the highest seminiferous tubular epithelium was highest 76.63 ± 7.17 and the mean ± standard deviation of the highest seminiferous tubule diameter was highest at 219.98 ± 17.06 in the P3 group. The results of this study indicate that there were significant differences between groups with p
Solanum betaceum Extract as a Protective on Spermatozoa Morphology of Mice Exposed to Lead Acetate Rima Wirenviona; Reny I'tishom; Siti Khaerunnisa; Anak Agung Istri Dalem Cinthya Riris; Nurul Fatimah Susanti; Nurul Jannatul Wahidah; Abadiyah Zakiah Kustantina
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 5, No 1 (2021)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v5i1.4594

Abstract

Environmental pollution is one of the factors that contribute to the decline in male fertility. Lead is one of six air pollutants harmful to the reproductive system. One parameter of infertility in men is an increase in reproductive function observed with decreased morphological abnormalities of spermatozoa. The purpose is to analyze the effect of giving various dosages of Solanum betaceum extract on spermatozoa morphology of mice exposed to lead acetate. This study was true experimental using a randomized post-test only control group design. The total sample was 40 male mice Balb/ C taken by simple random sampling technique. Treatment and maintenance of experimental animals for 35 days. Statistical tests showed there were significant differences with p-value 0.005. Solanum betaceum extract can be used as a protective to improve the normal morphology spermatozoa of mice that exposed to lead acetate.
Potensi ekstrak Solanum betaceum terhadap peningkatan sel spermatogenik pada mencit (Mus musculus) yang dipapar timbal asetat Nurul Fatimah Susanti; Reny I’tishom; Siti Khaerunnisa
Riset Informasi Kesehatan Vol 9 No 1 (2020): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30644/rik.v9i1.377

Abstract

Background : Flavanoids are antioxidants that can prevent the negative effects caused by lead. The flavonoids contained in the Solanum betaceum extract have the potential to prevent the adverse effects of lead on the reproductive tract of rats because it can prevent oxidative stress. The purpose of this study was to prove the effect of Solanum betaceum extract on spermatogenic cells of mice exposed to lead acetate. The hypothesis in this study is that there is an effect of the administration of Solanum betaceum extract to an increase in the number of spermatogenic cells of mice (Mus musculus) exposed to lead Method : this type of research was a true experimental laboratory (true experimental), the research design uses a randomized posttest only control group design approach. The total sample of 40 heads was divided into 5 groups. Group K-: control group without the provision of lead acetate and Solanum betaceum extract, group K +: group with 75 mg / KgBB of lead acetate for 32 days, group P1: group of treatment with 75 mg / KgBB of lead acetate extract + Solanum betaceum extract for 31 days + group 100 mg / gBB for 35 days, group P2: treatment group with 75 mg / kg lead acetate for 31 days + Solanum betaceum extract 200 mg / KgBB for 35 days, and group P3: treatment group with 75 mg lead acetate KgBB for 31 days + Solanum betaceum extract 400 mg / gBB for 35 days.. Results : The mean ± standard deviation of the highest cell spermatogenic was highest 2107.88±78.70.Conclusion : The administration of Solanum betaceum extract can increase the thickness of the seminiferous tubules epithelium and the diameter of the seminiferous tubules in rats (Mus musculus) which are exposed to lead acetat.
Strategies For Building A Golden Generation Through Balanced Nutrition Education For Pregnant Women Nurul Jannatul Wahidah; Rima Wirenviona; Susanti, Nurul Fatimah; Abadiyah Zakiah Kustantina
ABDIMAS: Jurnal Pengabdian Masyarakat Vol. 8 No. 2 (2025): ABDIMAS UMTAS: Jurnal Pengabdian Kepada Masyarakat
Publisher : LPPM Universitas Muhammadiyah Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35568/abdimas.v8i2.6544

Abstract

Achieving a golden generation begins with ensuring optimal health and development during the earliest stages of life, particularly through maternal nutrition. This study underscores the critical role of balanced nutrition education for pregnant women in promoting healthy fetal growth and long-term maternal and child well-being. A structured educational intervention was designed to equip pregnant women with comprehensive knowledge on essential nutrients, appropriate meal planning, and the lifelong impact of proper dietary practices. The study engaged 32 pregnant participants and employed a pre- and post-test design to evaluate changes in nutritional knowledge. The results revealed a marked and statistically significant improvement in participants' understanding following the intervention. These findings highlight the effectiveness of targeted, community-based education in enhancing maternal nutritional literacy, thereby contributing to improved pregnancy outcomes and supporting the foundation for a healthier future generation.Keywords: golden generation, balanced nutrition, pregnant women, nutrition education, maternal health.
Faktor-Faktor yang Mempengaruhi Komunikasi Orang Tua-Remaja dalam Isu Kesehatan Seksual dan Reproduksi: Tinjauan Literatur Sistematis Susanti, Nurul Fatimah; Octaliana, Hasrita; Listya, Endah Purda
Media Kesehatan Politeknik Kesehatan Makassar Vol 20 No 1 (2025): Media Kesehatan
Publisher : Direktorat Politeknik Kesehatan Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/medkes.v20i1.1416

Abstract

Adolescents are individuals aged 10–18 years. Adolescents who have sufficient knowledge about sexual and reproductive health issues can make wise decisions and avoid risky behavior. Parents are the closest people to provide information, guide, and encourage adolescents in their attitudes toward reproductive health. Parent-adolescent communication plays an important role in reducing risky sexual behavior and preventing various sexual and reproductive health problems. The purpose of this study is to update and provide a comprehensive overview of the factors that influence parent-adolescent communication about reproductive health issues. A literature review was conducted using the PubMed and ScienceDirect databases. Article selection methods used PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) and were reviewed using the PICO framework (Participants, Interventions, Comparisons, and Outcomes). Keyword searches used a combination of keywords with Boolean operators (AND). Out of 1,133 articles found, 306 were selected for the study objectives and abstracts. Subsequently, selection was conducted according to inclusion criteria. Inclusion criteria were articles published between 2020 and 2025, quantitative research design, written in English, and all articles were free and accessible. Analysis of the 6 articles revealed that factors influencing parental communication with adolescents about sexual and reproductive health include parental education (3 articles), parental knowledge (3 articles), adolescents' attitudes toward sexual and reproductive health issues, and adolescents' awareness of accessing information about sexual and reproductive health (3 articles). The results of this study indicate the need for integrated reproductive health education that targets not only adolescents but also parents through various strategies, such as regular counseling conducted by relevant health care facilities. This educational program should be designed to enhance parents' knowledge, communication skills, and confidence in discussing sexual and reproductive issues openly and age-appropriately. Keywords: Communication; Parents; Adolescents; Sexual and reproductive health
BERAT LAHIR BAYI DIHUBUNGKAN DENGAN STATUS GIZI IBU HAMIL KURNIA PRATAMA, RINI MUSTIKASARI; DAMAYANTI, DAMAYANTI; OCTALIANA, HASRITA; LISTYA, ENDAH PURDA; SUSANTI, NURUL FATIMAH; KURNIA PRATAMA, BELLA PRATIWI
Journal Of Midwifery Vol 13 No 1 (2025)
Publisher : UNIVED PRESS, Universitas Dehasen Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pendahuluan: Indonesia memiliki masalah gizi anak dengan presentase Bayi Berat Lahir Rendah (BBLR) mencapai 6,2%. Ibu hamil dengan kekurangan gizi berisiko melahirkan bayi dengan berat lahir rendah 2-3 kali lebih besar dibandingkan ibu hamil yang tidak mengalami kekurangan gizi dan kemungkinan bayi meninggal 1,5 kali lebih besar. KEK saat hamil juga dapat meningkatkan risiko terjadinya BBLR. Tujuan penelitian ini adalah mengkaji faktor determina berat lahir bayi ditinjau dari keadaan ibu yang berisiko KEK. Metode: Penelitian ini menggunakan desain penelitian observasional analitik dengan pendekatan cross sectional. Lokasi penelitian di Wilayah Kerja Puskesmas Talang Bakung, Kota Jambi. Sampel diambil menggunakan teknik purposive sampling sebanyak 30 orang ibu hamil dengan kriteria inklusi. Pengukuran Lingkar Lengan Atas (LiLA) sebagai penilaian KEK dilakukan menggunakan pita LiLA pada sepertiga lengan ibu hamil bagian atas. Analisa data menggunakan uji chi-square. Hasil dan Pembahasan: Variabel KEK menggunakan uji Fisher’s Exact diperoleh p-value 0,063 dimana lebih besar dari 0,05 sehingga tidak terdapat hubungan KEK dengan berat badan lahir bayi, dengan sebagian besar ibu hamil tidak mengalami KEK melahirkan bayi dengan berat lahir normal (46,7%). Kesimpulan: Tidak terdapat hubungan KEK dengan berat badan lahir bayi, dimana KEK tidak dapat dijadikan sebagai faktor determinan berat lahir bayi. Diharapkan penelitian selanjutnya dapat lebih banyak lagi mengkaji tentang faktor-faktor dari ibu hamil yang dapat memengaruhi berat badan lahir dengan menggunakan sampel yang lebih besar dan cakupan wilayah kerja yang lebih luas.