Article Per Year (5 Year)
p-Index From 2020 - 2025
1.116
P-Index
This Author published in this journals
All Journal JIMKesmas (Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat) Indonesia Chimica Acta Al-Kimia Jurnal Biotek Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Ruwa Jurai: Jurnal Kesehatan Lingkungan Helium: Journal of Science and Applied Chemistry
Santi Santi
STIKes Mega Rezky Makassar
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Energy Environmental Science Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Other

Published : 9 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Indonesia Chimica Acta

 1 
Exploring the Role of HEPES Buffer in the Synthesis and Characterization of Lanthanide-Nucleotide Complexes Santi, Santi; Amirah; Putri Salsabila, Nabila
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 17, No 2: December 2024
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70561/ica.v17i2.41123

Abstract

Lanthanide-nucleotide complexes are of interest due to their unique luminescent properties and have potential applications in a wide range of fields from medical imaging to environmental sensing. Given the sensitive nature of biochemical reactions, the choice of reaction conditions including pH plays a crucial role in determining the synthesis yield. One of the buffering agents that has gained prominence in this synthetic methodology is HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid). This study investigates the role of HEPES buffer in maintaining stable pH conditions, which are critical for the successful formation of lanthanide-nucleotide complexes. Terbium complexes with adenosine triphosphate ligands have been successfully synthesized with a maximum reaction time of 60 minutes. The complex was characterized using a UV-Vis spectrophotometer where the absorption peak at a wavelength of 257.5 nm indicates the occurrence of π-π* electron transitions. There is an absorption band at a wavelength of 349 cm-1 in the TbATP complex using an FT-IR spectrophotometer, this can be associated with the vibration of the Tb-N bond, which confirms the formation of a terbium complex with adenosine triphosphate. A sharp infrared absorption band at a wavelength of 630 cm-1 indicates the presence of vibrations of the O-H bond bound to the terbium ion, namely the formation of a Tb-OH complex bond, indicating that the phosphate group in ATP is involved in the formation of the complex.
Co-Authors Al Maratun Sholihati Amirah Amirah Aznawi Arlitha Akbar Indas Wari Rahman Kasmuddin Darmo Ka’bah Paharu Maswati Baharuddin Miladiarsi Miladiarsi Nurfardila Nurfardila Nurmala Sari Putri Salsabila, Nabila Rachma Rachma Shafitri, Dian Sulfiani, Sulfiani Tabalessy, Oliviane Katherina Zindy Devi