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All Journal JIMKesmas (Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat) Indonesia Chimica Acta Al-Kimia Jurnal Biotek Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Ruwa Jurai: Jurnal Kesehatan Lingkungan Helium: Journal of Science and Applied Chemistry

Santi Santi

STIKes Mega Rezky Makassar

Author-ID : 2672069

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Energy Environmental Science Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Other

Published : 9 Documents Claim Missing Document

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Articles

Kinetika Adsorpsi Ion Logam Pb (II) pada Karbon Aktif dengan Gelombang Ultrasonik Santi Santi
Al-Kimia Vol 3 No 1 (2015): June
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Adsorption capacity Increase of the activated carbon can be done with the use of ultrasonic energy-producing high chemical. Activated carbon is used to absorb the metals Pb(II) with a variety of time. Research purposes to determine the effect of variation of contact time on the adsorption of Pb(II) using rice husk activated carbon irradiated with ultrasonic waves and without irradiation. Determining the reaction kinetics model (reaction order and k values) of Pb (II) using rice husk activated carbon irradiated with ultrasonic waves. The results showed the optimum time on the adsorption process of Pb(II) by rice husk activated carbon is irradiated with ultrasonic waves were 50 minutes, whereas the adsorption process of Pb (II) by rice husk activated carbon without irradiated with wave ultrasonic is 30 minutes. Reaction kinetics of Pb(II) according to the pseudo-second-order kinetic model and the value of k2 = 0.0472 g. mg-1.min-1.

Produksi dan Uji Aktivitas Enzim Selulase dari Bakteri Bacillus subtilis Al Maratun Sholihati; Maswati Baharuddin; Santi Santi
Al-Kimia Vol 3 No 2 (2015): December
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Enzyme cellulose can be produced from bacteria Bacillus subtilis. This bacteria is a kind of bacteria which grounded on the genus that can degrade cellulose to glucose. Cellulase enzyme acquired different optimum pH and temperature depends on the bacteria. This research aim to produce and analyze the activity of the cellulose enzyme from bacteria Bacillus subtilis at optimum pH and temperature. The research of this enzyme cellulose derived by prolific process and rejuvenation bacteria Bacillus subtilis on the nutrition culture, nutrition selective, and nutrition production that executed by cold centrifugation to obtain extract or the enzyme cellulose at the temperature of 4°C, 3500 rpm within 15 minutes. On the determine pH with variety pH 5,6 using buffer acetat and pH 6,0; 6,5; 7,0; 7,5; and 8.0 using phosphate buffer while on the determine temperature using variety temperature 25°C, 30°C, 35°C, 40°C, 45°C, and 50°C which the next make an experiment activity enzyme cellulose by method Nelson-Somogy that measured in spectrophotometer UV-Vis of λ 540 nm. The result shows that the highest enzyme activity at optimum pH of 6, 0 is 4,3661 10ˉ3 U/mL and in optimum temperature of 30°C as is 5,6609 10ˉ3 U/mL.

Potensi Zat Warna dari Ekstrak Etanol Kayu Sappang Sebagai KalorimetriAnion Nurmala Sari; Rachma Rachma; Santi Santi
Al-Kimia Vol 5 No 2 (2017): December
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Dye from Sappang Tree has been isolated using ethanol as a solvent. Braziline is one of the chemical compound found in the ethanol extract. The Compound can be used as anion calorimethric due to their active sites of hydroxyl and chromophore groups. Dyes from sappang tree has been tested on 10 g of several types of saturated anions (carbonate, sulfate, phosphate, cyanide, acetate, borax, nitrite, chloride, bromide, and iodide). The results of the tests show that the color of the dye from changes in carbonate, phosphate, cyanide, acetate, nitrite, and hydroxyl. Spectrophotometer UV/Vis is used to detect the limit of cyanide anion. Metanol and acetone show positive results on the dye in cyanide anion. Detection limit of braziline is 3x10-4 M. By addition of cyanide anion, the dye has detection limit at 1x10-4 M.

ANALISIS KADAR SGPT PADA PASIEN MULTIDRUG RESISTANT TUBERKULOSIS (MDR-TB) DI BALAI BESAR KESEHATAN PARU MASYARAKAT MAKASSAR (BBKPM) Arlitha Akbar; Santi Santi; Kasmuddin Darmo; Zindy Devi; Amirah Aznawi; Ka’bah Paharu
(Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat) Vol 7, No 3 (2022): JIMKesmas (Jurnal Ilmiah Kesehatan Masyarakat)
Publisher : Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37887/jimkesmas.v7i3.31459

AbstrakTuberkulosis adalah penyakit kronik menular yang disebabkan oleh Mycobacterium tuberculosis. Pengobatan tuberkulosis yang tidak efektif akan menyebabkan seseorang terkena multidrug resistant tuberkulosis. Pada kasus MDR-TB yang gagal dalam pengobatan yang menjadi salah satu masalah untuk pengendalian MDR-TB dikarenakan dapat menjadi salah satu sumber penyebaran Mycobacterium tuberculosis dengan resisten pengobatan, penularan kontak Mycobacterium tuberculosis yang sudah mengalami resistensi obat akan menciptakan kasus yang baru dan pada penderita MDR-TB yang sudah mengalami resistensi primer. Kasus MDR-TB meningkat menjadi salah satu masalah krisis dalam kesehatan masyarakat dan dapat mengancam keamanan kesehatan dunia Penggunaan obat pada pasien MDR-TB mempengaruhi kadar SGPT melalui sifat hepatoksik obat yang dapat mempengaruhi fungsi hati. Tujuan penelitian ini mengetahui kadar SGPT pada pasien multidrug resistant tuberkulosis (MDR-TB) dengan jenis penelitian deskriptif analitik. Adapun jumlah subjek penelitian sebanyak 20 responden. Penelitian dilakukan dengan menggunakan metode semi automatik dengan alat selectra. Hasil penelitian menunjukkan bahwa ditemukan hasil pemeriksaan SGPT yang normal (100%) pada semua sampel yang di periksa. Pada penelitian ini dapat disimpulkan bahwa semua sampel dinyatakan normal dimana memperlihatkan bahwa terjadinya pemutusan atau jeda pengobatan pada MDR-TB tidak mempengaruhi kelainan hati. Kata Kunci : Hepatoksik, MDR-TB, Selectra, SGPT

Uji Diagnostik Jamur Dermatofita Pada Luka Kaki Penderita Diabetes Melitus dengan Metode PCR (Polymerase Chain Reaction) Miladiarsi Miladiarsi; Indas Wari Rahman; Santi Santi; Nurfardila Nurfardila
Jurnal Biotek Vol 11 No 1 (2023): JUNI
Publisher : Department of Biology Education of Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jb.v11i1.31707

Copyright©2023 Diabetic wounds often occur in people with diabetes mellitus as a result of impaired tissue perfusion and fungal infections, one of which is excessive dermatophytes that cause tissue death. This study aims to detect dermatophyte fungi in foot wounds of diabetics with diabetes mellitus by the Polymerase Chain Reaction (PCR) method. The type of laboratory observational study with a cross sectional study design, and the sampling technique used is total sampling by swab foot wounds in diabetes mellitus patients. The research method uses the PCR method to detect the presence or absence of dermatophyte fungi characterized by the formation of DNA fragments on electrophoresis visualization. The results showed that from 8 samples detected, 5 samples or 62.5% were positive for dermatophyte fungal infection based on amplification results marked by the formation of an amplicon DNA target band measuring around 700-1000 bp using ITS1 primers (forward: 5' GGT TGG TTT CTT TTC CT 3') and ITS2 (reverse: 5' AAG TAA AAG TCG TAA CAA GG 3'), so it can be concluded that in identifying samples using the PCR (Polymerase Chain Reaction) method has a high sensitivity in detecting fungi so as to allow more specific and more accurate results.

Edukasi Bahan Tambahan Pangan yang Halal, Sehat dan Bergizi untuk Masyarakat Kelurahan Talaka Santi Santi
Warta Pengabdian Andalas Vol 30 No 4 (2023)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.30.4.732-738.2023

Food is one of the basic human needs, and food is usually given food additives. However, public knowledge about food additives still needs to be improved in terms of type, appropriate dosage for use and impact on human health. Apart from being good, food must also be halal, but public understanding of halal food ingredients and the contamination of non-halal ingredients into food is still lacking. This community service activity aims to increase public knowledge, especially in Talaka village, about food additives that are halal, healthy and nutritious and to be able to recognize products that contain food additives that are dangerous to health. This activity was carried out through introductions, giving pre-test questionnaires, providing education on halal, healthy and nutritious food, and giving a post-test afterwards. Nineteen participants answered questions correctly before education was 50%, while after education it was improved to 75%. Based on the results of observations and discussions with counselling participants, information was obtained that the public already understands the importance of choosing food products that are hygienic, halal, healthy and nutritious and that the public knows about additional ingredients—permitted and prohibited foods for food products.

The Effect of Distillation on Ethanol Content in Sageru and Sopi Samples from Enau Trees (Arenga Pinnata) Using UV-Vis Spectrophotometer Tabalessy, Oliviane Katherina; Santi, Santi
Helium: Journal of Science and Applied Chemistry Vol 4, No 1 (2024): Helium: Journal of Science and Applied Chemistry
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/helium.v4i1.9961

Sopi is a traditional Maluku alcoholic drink produced from the fermentation of sageru from tapping palm trees (Arenga pinnata), one of the ingredients of which is ethanol. The research aimed to determine the ethanol content of sageru and beef samples from traditional and steam distillation. This experimental research method uses the UV-Vis spectrophotometer method to determine the effect of distillation on ethanol levels in sageru and sopi samples from Enau trees (Arengan pinnata). Based on the results of the quantitative analysis carried out using the UV-Vis spectrophotometry method, it was found that the alcohol content in traditional drinks (sageru and sopi) from palm plants (Arenga pinnata) was (13%-29%), which falls within the provisions of BPOM RI No. 6 of 2018 states that drinks that have ethyl alcohol or ethanol levels of more than 20% to 50% are included in group C. So, it can be concluded that the ethanol content was obtained in the sageru sample resulting from distillation at a temperature of 50 ºC to 78 ºC (13% - 27%). Ethanol levels were found in samples of traditional distilled beef (24% - 29%).

Exploring the Role of HEPES Buffer in the Synthesis and Characterization of Lanthanide-Nucleotide Complexes Santi, Santi; Amirah; Putri Salsabila, Nabila
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 17, No 2: December 2024
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70561/ica.v17i2.41123

Lanthanide-nucleotide complexes are of interest due to their unique luminescent properties and have potential applications in a wide range of fields from medical imaging to environmental sensing. Given the sensitive nature of biochemical reactions, the choice of reaction conditions including pH plays a crucial role in determining the synthesis yield. One of the buffering agents that has gained prominence in this synthetic methodology is HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid). This study investigates the role of HEPES buffer in maintaining stable pH conditions, which are critical for the successful formation of lanthanide-nucleotide complexes. Terbium complexes with adenosine triphosphate ligands have been successfully synthesized with a maximum reaction time of 60 minutes. The complex was characterized using a UV-Vis spectrophotometer where the absorption peak at a wavelength of 257.5 nm indicates the occurrence of π-π* electron transitions. There is an absorption band at a wavelength of 349 cm-1 in the TbATP complex using an FT-IR spectrophotometer, this can be associated with the vibration of the Tb-N bond, which confirms the formation of a terbium complex with adenosine triphosphate. A sharp infrared absorption band at a wavelength of 630 cm-1 indicates the presence of vibrations of the O-H bond bound to the terbium ion, namely the formation of a Tb-OH complex bond, indicating that the phosphate group in ATP is involved in the formation of the complex.

ANALISA KADAR HDL DAN LDL PADA PEROKOK KONVENSIONAL DAN PEROKOK ELEKTRIK (VAPE) Shafitri, Dian; santi, Santi; Sulfiani, Sulfiani
Ruwa Jurai: Jurnal Kesehatan Lingkungan Vol. 18 No. 2 (2024)
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/rj.v18i2.4490

Latar belakang: Merokok merupakan kebiasaan berbahaya bagi kesehatan yang merusak dinding pembuluh darah. Nikotin yang terkandung dalam asap rokok baik rokok konvensional maupun rokok elektrik (vape) akan merangsang hormon adrenalin yang akan merubah metabolisme lemak sehingga kadar HDL (High Density Lipoprotein) di dalam aliran darah menurun dan kadar LDL (Low Density Lipoprotein) dalam darah meningkat. Penelitian ini bertujuan untuk mengetahui kadar HDL dan LDL pada perokok konvensional dan perokok elektrik (vape).Metode: Jenis penelitian ini menggunakan deskriptif kuantitatif dengan pendekatan cross sectional. Penelitian ini dilakukan di RSUD Labuang Baji, dengan jumlah responden sebanyak 20 orang terdiri dari 10 perokok konvensional dan 10 perokok elektrik (vape).Hasil: Penurunan kadar HDL pada perokok konvensional sebanyak 7 responden (70%), tinggi sebanyak 3 responden (30%) pada perokok elektrik (vape) penurunan kadar HDL sebanyak 10 responden (100%). Hasil kadar LDL perokok konvensional dengan klasifikasi optimal 4 responden (40%), hampir optimal 2 responden (20%), ambang batas tinggi 3 responden (30%) dan tinggi 1 responden (10%), pada perokok elektrik (vape) dengan klasifikasi optimal 2 responden (20%), hampir optimal 1 responden (10%), ambang batas tinggi 5 responden (50%) dan tinggi 2 responden (20%).Simpulan: Dari hasil penelitian diharapkan bahwa masyarakat menjaga pola hidup yang sehat serta mengurangi konsumsi rokok.

Co-Authors Al Maratun Sholihati Amirah Amirah Aznawi Arlitha Akbar Indas Wari Rahman Kasmuddin Darmo Ka’bah Paharu Maswati Baharuddin Miladiarsi Miladiarsi Nurfardila Nurfardila Nurmala Sari Putri Salsabila, Nabila Rachma Rachma Shafitri, Dian Sulfiani, Sulfiani Tabalessy, Oliviane Katherina Zindy Devi

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