Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Journal of Food and Pharmaceutical Science Jurnal Kesehatan
Wisdawati Wisdawati
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
AKTIVITAS ANTIOKSIDAN Caulerpa lentillifera J.Agardh DENGAN METODE PEREDAMAN RADIKAL BEBAS 1,1-diphenyl-2 picrylhydrazil Selpida Handayani; Ahmad Najib; Wisdawati Wisdawati; Anisatul Khoiriyah
Jurnal Kesehatan Vol 13 No 1 (2020): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v13i1.13848

Abstract

Green caviar (Caulerpa lentillifera J. Agardh) contains substances which potentially act as antioxidant. This research aim to determine the antioxidant activity of Green caviar extract using free radical scavenging method by 1,1-Diphenyl-2 Picrylhydrazil (Dpph). Green caviar was extracted with sequences extraction using n-hexane, ethyl acetate, and etanol 96% with the yield value for n-hexane, ethyl acetate, and ethanol are 2.256%, 4.176%, 5.548% respectively. Furthermore, the chemical contents of each extract were identified using phytochemical screening and TLC qualitative test with n-hexane : ethyl acetate ( 8 : 2 ) as mobile phase and silica gel 60 F254 as stationary phase. The results showed that each green caviar extract has antioxidant activity with IC50 value of n- hexane extract 61.057 μg/mL identified as moderate antioxidant (50-100 μg/mL) ethyl acetate extract 41.756 μg/mL included as strong antioxidant (10-50 μg/mL), and ethanol 96 % which is 52.116 μg/mL classified as moderate antioxidant (50-100 μg/mL). Ethyl acetate is the best solvent to be used to extracting the antioxidant compounds of Green caviar.
Lemongrass (Cymbopogon citratus) Essential Oil Ointment for Topical Therapy: Wound Healing Efficacy, Anti-Inflammatory Response, and Skin Irritation Assessment in Animal Models Wisdawati Wisdawati; Andi Trihadi Kusuma Kisra; Rais Razak; Selpida Handayani; Irma Santi; Dewi Yuliana
Journal of Food and Pharmaceutical Sciences Vol 14, No 4 (2026): J.Food.Pharm.Sci (In Press)
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.27082

Abstract

Lemongrass (Cymbopogon citratus), containing citronellal, geraniol, and limonene, has demonstrated wound healing and anti-inflammatory potential. Lemongrass extract has been found to increase fibroblast numbers in rats, and formulated ointment containing its essential oil exhibit good characteristics. This study evaluated the wound healing, anti-inflammatory, and skin irritation potential of lemongrass essential oil ointment. Wound healing activity was assessed to compare  three formulation (F1:5%, F2: 10% and F3: 15%). Incision wounds were made in all groups and then treated according to groups assignment, the healing progression was measured on days 0, 3, 7, 10, 14 and 21. The ointment enhanced wound closure in a dose-dependent manner. As in the anti-inflammatory test, five animal groups were employed, with the positive group replaced by HOT-IN DCL emulgel®. Edema volume was recorded hourly for five hours following carrageenan induction. Also, the ointment demonstrated dose-dependent manner of anti-inflammatory activity. Skin irritation was evaluated according to non-clinical toxicity guidelines using three formulations on rabbit skin, and responses were scored using the Primary Irritation Index (PII). All formulations showed a PII value of 0, indicating negligible irritation. These findings support the potential of lemongrass essential oil ointment as a safe candidate for topical therapeutic development.
Co-Authors Ahmad Najib Andi Trihadi Kusuma Kisra Anisatul Khoiriyah Dewi Yuliana Irma Santi Rais Razak Selpida Handayani Selpida Handayani