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SYIFA HANIFAH
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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REVIEW : AKTIVITAS ANTIHIPERLIPIDEMIA ANGKAK SYIFA HANIFAH; TIANA MILANDA
Farmaka Vol 17, No 3 (2019): Farmaka (Desember)
Publisher : Fakultas Farmasi, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2077.397 KB) | DOI: 10.24198/jf.v17i3.22075

Abstract

Abstrak Hiperlipidemia adalah kondisi penumpukkan lipid secara berlebih dalam darah, yang disebabkan gangguan metabolisme lipid. Salah satu bahan alam yang diketahui memiliki aktivitas antihiperlipidemia adalah angkak, yaitu produk fermentasi beras oleh Monascus sp. Untuk mengetahui aktivitas antihiperlipidemia angkak, maka dilakukan penelusuran pustaka tentang angkak dari  jurnal nasional mapupun internasional bereputasi secara on line. Berbagai hasil penelitian menunjukkan bahwa angkak dan metabolit sekundernya, yaitu senyawa  monakolin, dapat menurunkan kadar kolesterol total, kadar LDL dan kadar trigliserida serta dapat menaikkan kadar HDL dalam darah. Monakolin, terutama monakolin K, dapat menginhibisi aktivitas (5-hidroksi-3-metilglutaril-koenzim A) reduktase, sehingga menghambat sintesis pembentukan kolesterol di hati, seperti halnya lovastatin. Angkak dapat digunakan dalam pengobatan dislipidemia pada pasien dengan SAMs (statin associated myalgias)  dan mengurangi kejadian kardiovaskular pada pasien jantung koroner dengan infark miokard. Angkak juga aman digunakan sebagai suplemen diet dalam jangka waktu lama, karena tidak memiliki efek toksik terhadap HMG-KoA reduktase. Kata kunci : Hiperlipidemia, Angkak, Monakolin, Lovastatin Abstract Hyperlipidemia is the condition of the accumulation of lipids in excess in the blood, caused by disorders of lipid metabolism. Natural ingredients that are known to have activity antihyperlipidemic is angkak, which is the product of fermentation of rice by Monascus sp. To determine the activity of antihyperlipidemic angkak, then conducted a search of the literature about angkak from national and international journals of repute online. The results of various research shows that angkak and metabolites the secondary, i.e. compounds monakolin, can lower total cholesterol, LDL, triglyceride levels and can increase HDL levels in the blood. Monakolin, especially monakolin K, can inhibit the synthesis of cholesterol formation in the liver, as well as lovastatin. Angkak can be used in the treatment of dyslipidemia in patients with SAMs (statin associated myalgias) and reduce cardiovascular events in patients with coronary heart disease with myocardial infarction. Keywords: hyperlipidemia, Angkak, Monakolin, Lovastatin
Women’s Use of Social Media Durring the Iddah Period Following Divorce: A Perspektive Based Of Goffman’s Dramaturgy and Wahbah Zuhaili’s Fiqh Nur vita Ristiana; Naela Rosita; Azka Syifaul Maula; Syifa Hanifah; Naufal Faiq Mubarak
Hukum Islam Vol 26 No 2 (2026): Islamic Law
Publisher : Universitas Islam Negeri Sultan Syarif Kasim Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24014/vwq0z253

Abstract

The ease of using social media has transformed the patterns of self-expression among its users, including women undergoing the ‘iddah period following divorce. This study aims to analyse women’s social media practices during the ‘iddah period based on Erving Goffman’s dramaturgical theory, and to examine the legal implications from the perspective of Wahbah al-Zuhaili’s contemporary fiqh. This study employs a qualitative approach with a case study focus. Data were collected through in-depth interviews with three female informants currently undergoing the ‘iddah period, as well as through observation of their social media activities. Data analysis was conducted using thematic analysis with a socio-legal approach. The findings indicate that social media reveals a ‘front stage’ characterised by self-representation through social media posts that provoke negative comments, whilst the ‘back stage’ reveals unseen emotional dimensions, such as posting content driven by a need for public validation or validation from a former husband. This confirms that social media can also function as a space for identity construction that is inseparable from psychological dynamics. From the perspective of Wahbah al-Zuhaili’s fiqh, based on maqashid al-sharia, some of these digital behaviours are inconsistent with the principles of safeguarding honour, religion and social stability during the ‘iddah period. This study concludes that women’s social media practices during the ‘iddah period are influenced by social and emotional factors, as well as developments in digital technology.
Co-Authors Azka Syifaul Maula Naela Rosita Naufal Faiq Mubarak Nur Vita Ristiana TIANA MILANDA