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All Journal Farmaka Pharmacology and Clinical Pharmacy Research
Norisca A. Putriana
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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ARTIKEL TINJAUAN: MANFAAT KEFIR UNTUK KESEHATAN KULIT Mentari Luthfika Dewi; Taofik Rusdiana; Muchtaridi Muchtaridi; Norisca A. Putriana
Farmaka Vol 16, No 2 (2018): Farmaka (Agustus)
Publisher : Fakultas Farmasi, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (160.709 KB) | DOI: 10.24198/jf.v16i2.18052

Abstract

Kefir merupakan produk susu hasil fermentasi yang penggunaannya semakin populer karena terbukti secara ilmiah memiliki banyak manfaat bagi kesehatan. Penggunaan kefir tidak saja sebagai minuman probiotik untuk mengatasi permasalahan metabolisme tubuh, namun ternyata kefir memiliki banyak manfaat untuk memelihara kesehatan kulit dan mengatasi permasalahan kesehatan yang bermanifestasi pada kulit. Beberapa senyawa berkhasiat yang  terkandung di dalam kefir seperti peptida dan asam laktat menunjukan aktivitasnya sebagai inhibitor enzim tirosinase, selain itu senyawa-senyawa fenolik dalam kefir sangat efektif untuk mengatasi permasalahan kulit yang disebabkan oleh radikal bebas, dan sifat asam dari kefir sangat efektif untuk menghambat pertumbuhan beberapa jenis bakteri patogen terutama propionibacterium acnes. Artikel tinjauan ini betujuan untuk mengupas tuntas manfaat kefir terhadap kesehatan kulit khususnya sebagai agen pencerah kulit, antioksidan, anti jerawat dan mempercepat penyembuhan luka pada kulit beserta bukti ilmiahnya.
In-Vivo Effectiveness of 5% Azadirachta indica Oil Cream as Anti-Scabies Patihul Husni; Mayang K. Dewi; Norisca A. Putriana; Rini Hendriani
Pharmacology and Clinical Pharmacy Research Vol 4, No 1
Publisher : Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (231.947 KB) | DOI: 10.15416/pcpr.v4i1.21388

Abstract

Scabies is an infectious skin disease caused by mite Sarcoptes scabiei. Neem tree (Azadirachta indica) has the potential to be used as an anti-parasite due to the presence of azadirachtin compound that is commonly found in the seeds. The aim of this study was to evaluate in-vivo effectiveness of neem oil as an anti-scabies. This study used an experimental method.  The effectiveness of the cream as an anti-scabies was tested on New Zealand white rabbits which were infected with scabies. Permethrin cream was used as a positive control and cream base was used as a negative control.  Cream was applied once daily and left for 8 hours. The data were analyzed using Kruskal Wallis and Mann Whitney. Dermal acute irritation test was performed by applying  0.5 g cream on the rabbit dorsal. We found that 5% neem oil cream was effective as an anti-scabies with 20-21 days recovery time. The recovery time is longer than permethrin cream (7-8 days), but shorter compared to negative control with recovery time over 30 days. Primary irritation index for 5% neem oil creams was 0, indicating negligible irritation category. In conclusion, A. indica cream was effective for the treatment of scabies although its recovery time is shorter than permethrin cream.  Keywords: effectiveness test, irritation test, neem oil cream, scabies
Co-Authors Mayang K. Dewi Mentari Luthfika Dewi Muchtaridi Muchtaridi Patihul Husni Rini Hendriani Taofik Rusdiana