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Journal : Jaringan Laboratorium Medis

Gambaran Pemeriksaan Kadar SGOT dan SGPT pada Penderita Tuberkulosis Paru Siti Chairini; Widodo Widodo
Jaringan Laboratorium Medis Vol 2, No 1 (2020): May 2020
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v2i1.6266

Abstract

Liver disfunction is characterized by increased levels of SGOT and SGPT. The mechanism of liver disfunction by anti-tuberculosis drug (ATD) is not yet clearly known, but several research mention the occurrence of hepatotoxicity which caused by direct effect or through the complex production of drug enzyme which have consequences in cell disfunction as well as membrane disfunction. Hepatotoxicity due to ATD does not occur in each patient, but it could cause liver injury. research objective to find out the description of examination of SGOT and SGPT levels in patients of pulmonary tuberculosis. The research type was descriptive using medical records data and laboratory data of RSUP patients of pulmonary TB in January-March 2020. Research results : the normal SGOT levels in men 6-33 U/L as much as 63,33%, and SGOT normal 50-66 U/L as much as 2,35%. The normal SGOT levels in women 10-25 U/L as much as 25,88%, and SGOT normal in women 15-63 U/L as much as 8,24%. The normal SGPT levels in men 3-43 U/L as much as 62,35%, and SGPT normal 55-65 U/L as much as 3,53%. The normal SGPT levels in women 7-29 U/L as much as 34,12%. Hepatotoxicity based on SGOT levels as many as 9 people (10,59%), namely 2 men (elderly and old man) and 7 women (adolescent, adult, and elderly). Hepatotoxicity based on SGPT levels as many as 3 people (3,53%) in elderly and old man.
Skrining Gestational Diabetes Mellitus (GDM) pada Wanita Hamil dan Diabetes pada Lansia di Wilayah Getasan Widodo Widodo; Ahmad Riyadi; S.Y. Didik Widiyanto; Aulia Qurotul Ayuni
Jaringan Laboratorium Medis Vol 5, No 1 (2023): May 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i1.9661

Abstract

Type 1 and type 2 diabetes are influenced by genetic and environmental factors causing a decrease in β cell function resulting in hyperglycemia. Patients with hyperglycemia are at risk for chronic complications. The elderly have the potential to suffer from diabetes mellitus due to the age factor and the decreased ability of the body's metabolism. Whereas in pregnant women any hyperglycemia is considered gestational diabetes mellitus (GDM), regardless of diabetes occurring before or during the current pregnancy GDM is diabetes diagnosed in the second trimester or later. This study aims to map cases of diabetes and gestational diabetes. This research is a non-experimental study with a survey method approach without intervention that is descriptive analytic research results of 48 people with a total of 14 men and 5 pregnant women out of a total of 34 female respondents. Examination results for supporting examinations obtained the results of 8 glucose samples with levels 200 mg/dl and those who had diabetes mellitus based on HbA1c examination were 6 people aged 45-65 years and as many as 3 people aged over 65 years. Respondents who had diabetes mellitus were 2 men and 4 women and none of the pregnant women had gestational diabetes. This research has an impact on the people who take part in this activity, one of which is getting education on how to maintain a healthy quality of life in old age and for those who enter the diabetes mellitus screening group, it is continued in the process of care and assistance by the Getasan Health Center.