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Nicolas Layanto
Departemen Mikrobiologi, Fakultas Kedokteran, Universitas Kristen Krida Wacana
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Uji Fenotipik Deteksi Enzim ESBL, AmpC dan Karbapenemase pada Bakteri Enterobacteriaceae Ade Dharmawan; Nicolas Layanto
Jurnal Kedokteran Meditek Vol 25 No 3 (2019): SEPTEMBER - DESEMBER
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v25i3.1754

Abstract

Organisms that express extended-spectrum β-lactamase (ESBLs) such as Enterobacteriaceae have been increasing for the past forty years. Organisms that express this enzyme can hydrolyze oxyminocephalosporins and monobactam,but can be inhibited using β-lactam inhibitors. There are various types of enzymes that contribute to cephalosporin and monobactam resistances, such as AmpC β-lactamase, and carbapenemase enzymes. Polymerase Chain Reaction (PCR) is an accurate method for detecting ESBL, but this method is a genotypic method that requires a specialized instrument. Therefore there is a need for a phenotypic method to detect ESBL, AmpC and Carbapenemase that can be conducted in various laboratories.
Co-Authors Ade Dharmawan