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Mayuliani, Mayuliani
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Biochemistry, Genetics & Molecular Biology Immunology & microbiology Nursing Public Health

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HUBUNGAN LAMANYA PEMBERIAN MAGNESIUM SULFATE PADA PASIEN PEB DAN EKLAMPSIA DENGAN KEJADIAN HIPERMAGNESIUM DI RSUP DR. M. DJAMIL PADANG Mayuliani, Mayuliani; Djanas, Dovy
JOURNAL ANDALAS OBSTETRIC & GYNAECOLOGY Vol 2, No 1 (2018)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aogj.2.1.27-31.2018

Abstract

Tujuan?:?Untuk mengetahui hubungan lamanya pemberiaan MgS04 pada pasien PEB dan eklampsia dengan kejadian hipermagnesium.Metode?:?Penelitian ini merupakan observasional komparatif menggunakan desain cross sectional study. Penelitian dilakukan di rekam medis RSUP Dr.M.Djamil Padang selama periode 1 Januari 2016 sampai 31 Agustus 2017 terhadap ibu hamil dengan preeklampsia berat ( PEB) dan eklampsia, didapatkan 30 subyek penelitian yang memenuhi kriteria inklusi. Selanjutnya data dicatat dalam suatu formulir penelitian yang telah disediakan, kemudian dilakukan pengolahan data penelitian. Analisis statistik untuk menilai kemaknaan menggunakan uji chi-squere .Hasil:. Terjadi peningkatan kadar Magnesium pada ibu hamil dengan preeklampsia berat (PEB) dan eklampsia sebanyak 21 koresponden. Peningkatan kadar Magnesium terhadap pasien preeklampsia berat (PEB) dan eklampsia yang mendapatkan tatalaksana MgS04 selama 48 jam sebanyak 16 koresponden ( 84,2%) dan 5 koresponden dengan pemberian MgS04 selama 24 jam.Kesimpulan:?Terdapat hubungan yang bermakna lamanya pemberian Magnesium Sulfat dengan kejadian hipermagnesium pada pasien preeklamsia berat dan eklamsia.Kata kunci?:?PEB, eklampsia, magnesium sulfat, kadar Magnesium
HUBUNGAN LAMANYA PEMBERIAN MAGNESIUM SULFATE PADA PASIEN PEB DAN EKLAMPSIA DENGAN KEJADIAN HIPERMAGNESIUM DI RSUP DR. M. DJAMIL PADANG Mayuliani, Mayuliani; Djanas, Dovy
Andalas Obstetrics And Gynecology Journal Vol. 2 No. 1 (2018)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.2.1.21-25.2018

Abstract

Objective :To find out the relationship between the duration of MgS04 administration in severe preeclampsia patients and eclampsia with the incidence of hypermagnesium.Method :This study is a comparative observational study using a cross sectional study design. The study was conducted in the medical record of Dr.M.Djamil Padang Hospital during the period January 1, 2016 to August 31, 2017 of pregnant women with severe preeclampsia and eclampsia, found 30 study subjects who met the inclusion criteria. Furthermore, data is recorded in a research form that has been provided, then carried out research data processing. Statistical analysis to assess significance using the chi-square test.Results : Magnesium levels increased in pregnant women with severe preeclampsia and eclampsia by 21 correspondents. Increased Magnesium levels in patients with severe preeclampsia and eclampsia who received MgS04 treatment for 48 hours by 16 correspondents (84.2%) and 5 correspondents with MgS04 administration for 24 hours.Conclusion : There is a significant relationship between the duration of Magnesium Sulfate with the incidence of hyperpermagnesium in patients with severe preeclampsia and eclampsia. Keywords: severe preeclampsia, eclampsia, magnesium sulfate, magnesium levels
Correlation of Brain Derived Neurotrophic Factors (BDNF) With Maternal and Perinatal Outcome in Preeclampsia Mayuliani, Mayuliani; Yusrawati, Yusrawati; Defrin, Defrin
Andalas Obstetrics And Gynecology Journal Vol. 5 No. 2 (2021)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.2.148-160.2021

Abstract

Objective: To analyze the correlation between BDNF and maternal and perinatal outcomes in preeclampsia.Methods: This was an observational analytic study with a cross-sectional design on 73 pregnant women with preeclampsia. The study began in January 2020 to June 2020 in the Obstetrics and Gynecology Department of Dr M. Djamil Hospital Padang.Results: The mean BDNF levels of pregnant women with preeclampsia were 519.9 ± 325.4 pg/ml. The correlation between BDNF and systolic blood pressure, diastolic blood pressure, and Mean Arterial Pressure was negatively correlated (r = -0.145, -0.1, and -0.218), with a weak correlation. There was no statistically significant relationship between BDNF and systolic blood pressure, diastolic blood pressure, and mean arterial pressure (p> 0.05). BDNF correlation with infant birth weight and the birth length was positively correlated (0.196 and 0.205) with a weak correlation. The correlation between BDNF level and Apgar score was negatively correlated (-0.039 and -0.054) with a weak correlation. There was no statistically significant correlation between BDNF with birth weight, birth length, and Apgar score (p> 0.05).Conclusion: The mean BDNF level in preeclampsia was lower than normal pregnancy, there was a negative correlation between BDNF levels and maternal outcomes in preeclampsia with a weak correlation. There was a positive correlation between BDNF levels and perinatal outcomes (birth weight and birth length) in preeclampsia and there was a negative correlation between BDNF levels and Apgar score in preeclampsia with a weak correlation.Keywords: Brain Derived Neurotrophic Factors, Preeclampsia, Maternal Outcome, Perinatal Outcome
Co-Authors Defrin, Defrin Djanas, Dovy Djanas, Dovy Yusrawati Yusrawati