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Pengaruh Penggunaan Mesin Cardiopulmonary Bypass Terhadap Kadar Leukosit pada Operasi Bedah Jantung Rapto Hardian; Hariyo Satoto; Soenarjo Soenarjo
JAI (Jurnal Anestesiologi Indonesia) Vol 4, No 1 (2012): Jurnal Anestesiologi Indonesia
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v4i1.6435

Abstract

Latar belakang : Prosedur bedah jantung menggunakan mesin cardiopulmonary bypass semakin banyak dilakukan. Penggunaan mesin cardiopulmonary bypass dianggap menyebabkan peningkatan jumlah leukosit yang merupakan salah satu tanda terjadinya Systemic inflammatory response syndrome (SIRS).Tujuan : untuk mengetahui pengaruh penggunaan mesin cardiopulmonary bypass terhadap peningkatan jumlah leukosit pada operasi bedah jantung.Metode : merupakan penelitian cohort observational prospective pada 22 pasien yang menjalani operasi bedah jantung menggunakan Cardiopulmonary bypass. Pengambilan sampel darah tepi untuk menghitung leukosit diambil pada saat pra sternotomy (Leukosit 1), pra kanulasi (Leukosit 2), menit ke 15 (Leukosit 3) selama CPB dan menit ke 30 (Leukosit 4) selama CPB. Sampel darah dihitung menggunakan mesin secara otomatis. Uji statistik menggunakan Paired t-test dan Wilcoxon signed ranks test (dengan derajat kemaknaan < 0,05).Hasil : karakteristik data penderita akan disajikan dalam bentuk tabel. Pada penelitian ini didapatkan hasil uji pada Leukosit 2 dengan Leukosit 3 didapatkan hasil yang tidak bermakna p = 0,170 (p > 0,05 ). Hasil uji pada Leukosit 1 dengan Leukosit 2, Leukosit 1 dengan Leukosit 3, Leukosit l dengan Leukosit 4, Leukosit 2 dengan Leukosit 4, dan Leukosit 3 dengan Leukosit 4, didapatkan hasil yang bermakna dengan p = 0,019, p = 0,026, p = 0,001, p = 0,003 dan p = 0,007 (p < 0,05).Kesimpulan : terdapat peningkatan jumlah leukosit pada pemakaian mesin CPB terutama pada menit ke 30. Pada menit ke 15 belum terdapat peningkatan jumlah leukosit yang bermakna akibat pemakaian mesin CPB
COVID-19-free Pathway Provides Safety for Elective Surgery Patients from Hospital-acquired SARS-CoV-2 Infection Susianto, Oky; Adhi, Mahendratama; Fajar Rochman, Bagus; Hardian, Rapto; Meliandi, Yopi
Majalah Anestesia & Critical Care Vol 40 No 2 (2022): Juni
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif (PERDATIN) / The Indonesian Society of Anesthesiology and Intensive Care (INSAIC)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (341.833 KB) | DOI: 10.55497/majanestcricar.v40i2.248

Abstract

Background. Elective surgery during the COVID-19 pandemic must continue to prevent a backlog of surgical cases. Several institutions are implementing a COVID-19-free surgical pathway to minimize the risk of SARS-CoV-2 transmission. This study aimed to assess the safety of patients undergoing surgery against hospital-acquired SARS-CoV-2 infections by implementing a COVID-19-free pathway. Methods. This study is cross-sectional of 572 patients who underwent elective surgery with a COVID-19-free pathway. All patients underwent two days of quarantine in the hospital for RT-PCR testing. A negative COVID-19 test result is valid within 48 hours before surgery, and all surgeries were performed in a non-COVID-19 operating room. Age, gender, ASA classification, type of anesthesia, surgery criteria, length of stay, and ICU admission were the baseline characteristics of the patients in this study. The outcome in this study was hospital-acquired SARS-CoV-2 infections after the patient underwent surgery based on COVID-19 symptoms during hospitalization and 14 days after discharge. Results. This study involved 303 males (53%) and 269 females (47%) with a mean age of 40.16 years ± 11.35 years (12 days–84 years). According to the ASA classification, 44 patients (7.7%) ASA I, 450 (78.7%) ASA II, 77 (13.4%) ASA III and 1 (0.2%) ASA 4. Major or complex surgery criteria accounted for 48% (277) of all surgeries. One hundred and fifty-seven patients (27,4%) underwent postoperative hospitalization for 0-3 days, 190 (33.3%) 4-7 days, and 225 (39.3%) had a length of stay ≥ 8 days. None of the patients showed postoperative COVID-19 symptoms. Three patients died postoperatively, but their deaths were not COVID-19 related. Fourteen days after discharge, eight patients (3%) had fever and cough but did not perform the RT-PCR test. These eight patients experienced clinical improvement and recovery. Conclusion. Implementing a COVID-19-free pathway provides safety for patients from hospital-acquired SARS-CoV-2 infections.
Anaesthetic Management for Patient with Trigeminal Neuralgia underwent Microvascular Decompression (MVD) Hardian, Rapto; Pratama, Edwin; Tarigan, Dwi Septwo Rustaminta; Sikumbang, Kenanga Marwan
Jurnal Neuroanestesi Indonesia Vol 13, No 2 (2024)
Publisher : https://snacc.org/wp-content/uploads/2019/fall/Intl-news3.html

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24244/jni.v13i2.600

Abstract

Trigeminal neuralgia (TN) is a chronic pain with repeated brief episodes of electric shock-like pain affecting the fifth cranial nerve. Microvascular decompression (MVD) is one of treatments for TN. Anesthetic management for MVD requires special consideration to reduce brain volume (slack brain) and optimise Mean Arterial Pressure (MAP). Female 29-yo, 40kgbw with chief complaint: throbbing pain and intermittent stiffness in right facial area since 1 year ago. Brain MRI examination showed crossing of right superior cerebellar artery (RSCA) branch with right trigeminal nerve near the root entry zone and underwent MVD. Anesthesia using smooth intubation technique and maintenance using a combination of inhalational anaesthetics (sevoflurane 1 vol%) and intravenously (propofol 100mcg/kg/minute, remifentanil 0.2mcg/kgbw/min, and rocuronium 10mcg/kgbw/min). Target for MAP (90mmHg) and EtCO2 (30mmHg). We didn't use mannitol for slack brain. Early emergence with smooth extubation to prevent sudden haemodynamic changes and minimising coughing then for early neurological detection of intracranial complications.The combined use of sevoflurane 1MAC and continuous propofol provides optimal visualisation of the operating area. This combination reduces cerebral blood flow which makes the brain slack and keeps MAP optimal to maintain cerebral perfusion pressure and reduce the risk of cerebral ischemia. The combination of these agents also makes early recovery for more rapid neurological assessments. Anaesthesia management for MVD uses neuroanesthesia principles, balanced anaesthesia, and strict haemodynamic monitoring. The combination of inhalation anaesthetic sevoflurane and intravenous propofol gave optimise visualisation in the operation area and the patient's recovery can be enhanced
Durasi Operasi yang Memanjang pada Pasien dengan Tumor Cerebellopontine Angle (CPA) Harrison, Harrison; Sikumbang, Kenanga M.; Hardian, Rapto
Jurnal Neuroanestesi Indonesia Vol 9, No 1 (2020)
Publisher : https://snacc.org/wp-content/uploads/2019/fall/Intl-news3.html

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (401.204 KB) | DOI: 10.24244/jni.v9i1.242

Abstract

Tumor Cerebellopontine angle (CPA) merupakan tumor fossa posterior terbanyak dan merupakan 5-10% dari tumor intrakranial. Penatalaksanaan anestesi pada kasus tumor CPA sangat menantang, dan memerlukan perhatian khusus terhadap disfungsi batang otak, posisi pasien, pemantauan neurofisiologi intraoperatif, dan adanya risiko venous air embolism (VAE). Pasien wanita, 16 tahun, 45 kg, suspek CPA tipe schwannoma akustik dengan keluhan sakit kepala selama 2 bulan. Tidak ada riwayat tinitus dan gangguan keseimbangan. CT-scan kepala memperlihatkan massa padat dengan bagian kistik di cerebellopontine angle kanan. Prosedur pembedahan dilakukan dalam posisi prone dan memanjang hingga 13 jam. Rumatan anestesi ditujukan untuk stabilisasi hemodinamik dan pencegahan hipotermia dengan penghangat blower dan infus hangat. Perdarahan selama pembedahan sekitar 1800 ml. Pasien diekstubasi setelah 3 hari di ICU. Prosedur bedah untuk tumor CPA memiliki risiko tinggi dan membutuhkan waktu lama, sehingga meningkatkan mortalitas dan morbiditas akibat risiko hipotermia dan ketidakstabilan hemodinamik yang lebih tinggi. Pada kasus ini dengan keterbatasan alat monitoring, dilakukan observasi ketat untuk kejadian VAE dan pencegahan komplikasi pascabedah dengan menjaga hemodinamik tetap stabil dengan pemberian cairan adekuat dan pencegahan hipotermia dengan penggunaan blower warmer dan infus hangat. Pada kasus ini, lama pembedahan selama 13 jam diantisipasi dengan monitoring yang ketat, pemberian volume adekuat dan pencegahan hipotermi.Prolonged Operation in Patient with Cerebellopontine Angle (CPA) TumorAbstractCerebellopontine angle (CPA) tumor is the most common neoplasms in the posterior fossa, accounting for 5-10% of intracranial tumors. Anesthetic management is very challenging and needs special attention due to brain dysfunction, patient position, neurophysiological monitoring intraoperative, and the risk of venous air embolism (VAE). Female patient, 16 years old, 45 kg, with a suspected CPA acoustic schwannoma presented headache for 2 months. No history of tinnitus and balance disorders. Head CT-scan showed solid mass with cystic sections at right cerebellopontine angle. During procedure patient was in prone position and the operation took 13 hours long. Maintenance anesthesia aims to stabilize hemodynamic with adequate fluid replacement and prevention hypothermia with blower warmer and fluid warmer. Blood loss during the operation about 1800 ml. The patient was extubated after 3 days in the ICU. Surgical procedure in cerebellopontine angle surgery has a high risk and requires a long time. Prolonged duration of surgery will increases mortality and morbidity, because of the higher risk of hypothermia and hemodynamic instability. With limited monitoring equipment, we stabilize hemodynamic and to prevent the risk of VAE by adequate volume replacement. Hypothermia prevention by blower and fluid warmer. In this case, 13 hours long the operation makes us should maintenance hemodynamic by given adequate volume replacement and prevention of hypothermia.