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All Journal Amerta Nutrition World Nutrition Journal JITSI : Jurnal Ilmiah Teknologi Sistem Informasi
Levina Chandra Khoe
Universitas Indonesia
Computer Science & IT Health Professions Medicine & Pharmacology Nursing Public Health Other

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Journal : World Nutrition Journal

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Caesarean delivery mode and its impact on children’s growth and cognitive development Rini Sekartini; Levina Chandra Khoe
World Nutrition Journal Vol. 4 No. S2 (2020)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V04.S2.0004

Abstract

There is an increasing concern on the potential risk of Caesarean birth on child health outcomes. This study aims to present the current available evidences on the effect of Caesarean section on child’s growth and development. Literature searching were done on several online databases to identify articles which discussed the effect of Caesarean birth on child’s body weight, length, nutritional status, cognitive development, memory, learning ability, and intelligence quotient. Several studies showed positive association between Caesarean and risk of overweight and obesity in childhood, adolescence, and adulthood. While, there has not been sufficient evidences to confirm the association between C-section and child’s cognitive outcomes.
The impact of Caesarean delivery mode towards brain and neurodevelopment among children Tjhin Wiguna; Levina Chandra Khoe
World Nutrition Journal Vol. 4 No. S2 (2020)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V04.S2.0005

Abstract

In regards to the rising rate of Caesarean birth globally, there is concern about the risk of Caesarean birth in children. However, the effect of Caesarean delivery towards the child brain and neurodevelopment is not well understood. We reviewed articles from online database with topics related to the relation between caesarean delivery mode and brain development/neurodevelopment/behaviour and emotional development. Several studies discussed how birth mode could affect brain structural connectivity through neural and hormone changes. Some studies also assessed possible effect on child’s psychological development.  The result showed differences in child’s brain development between caesarean and natural delivery in the early life, but not in the long run. Additionally, no significant association between birth mode and emotional problem.
Immune development of children born from Caesarean section Zakiudin Munasir; Levina Chandra Khoe
World Nutrition Journal Vol. 4 No. S2 (2020)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V04.S2.0003

Abstract

Several studies results have shown that mode of delivery affects the health of children, and recent studies showed that elective cesarean section (CS) is associated with aberrant short-term immune responses in the newborn baby and an increased risk of developing immune disorders. This article focused on the effect and role of the C-section on the immune development in children. Begin at pregnancy, the infant's immune system is activated and develops years after birth. In this article we find that cesarean delivery mode will influence the offspring's immune system by disrupting the intestinal tract's bacterial colonization, different levels of birth adaptive stress, and altering gene expression epigenetic regulation. Some studies have found that gut microbiome composition plays a significant role in the development of immune system along with other factors such as diet/lifestyle, antibiotic use, formula feeding, vaccination with life vaccine, and pathogen exposure. In early life, disrupted colonization induced dysbiosis that was associated with lower Bifidobacteria and higher counts of C. difficile. These findings are related to infant immune disease and allergy. Dysbiosis following C-section has a huge effect of developing altered immune system, and this microbiome imbalance can be controlled by nutritional support such as maternal breast milk or the use of different combinations of prebiotics and probiotics (synbiotic) which could be beneficial for the immune and metabolic system.
Co-Authors Agus Sugiharto Dani Muhamad Trianto Endang Mariani Rahayu Muhammad Aji Muharrom Nuri Purwito Adi Reza Haryo Yudanto Rini Sekartini Tjhin Wiguna Zakiudin Munasir