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All Journal Medical Journal of Indonesia Sari Pediatri Paediatrica Indonesiana Medicinus : Jurnal Kedokteran World Nutrition Journal Proceedings of the International Conference on Nursing and Health Sciences Jurnal Muara Medika dan Psikologi Klinis
Rini Sekartini
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Physical activity levels and sleep disturbances in Indonesian primary school students during the COVID-19 pandemic Gunawan, Talitha Dinda; Sekartini, Rini
Paediatrica Indonesiana Vol. 64 No. 2 (2024): March 2024
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi64.2.2024.106-12

Abstract

Background During the coronavirus disease-2019 (COVID-19) pandemic, the Indonesian government implemented a large-scale, social restriction policy, including the closure of schools and recreational facilities, which potentially altered children’s physical activity and sleep patterns. Objective To analyze for a possible association between physical activity levels and sleep disturbances in Indonesian primary school students during the COVID-19 pandemic. Methods This cross-sectional study was conducted on 437 children aged 7-13 years using data collected online in April-August 2020, including children’s sociodemographic characteristics, physical activity levels, and sleep patterns. The translated Indonesian version of Physical Activity Questionnaire for Children (PAQ-C) and the Children Sleep Habits Questionnaire-Abbreviated (CSHQ-A) were used to collect data. The data analyzed consisted of sociodemographic factors and physical activity levels, sociodemographic factors and sleep disturbances, and physical activity levels and sleep disturbances. Results Most children were physically inactive (60.87%) and experienced sleep disturbances (73.23%) during the COVID-19 pandemic. Female sex and physical inactivity were significantly associated. Male sex and sleep disturbances were significantly associated. Age 7 as the lowest age group was significantly associated with sleep disturbances. There was no significant association (P=0.248) between physical activity levels and sleep disturbances. Conclusion Most Indonesian primary school students were physically inactive and had sleep disorders during the COVID-19 pandemic. Female sex and physical inactivity were significantly associated, while male sex and sleep disturbances were significantly associated, age 7 (lower age group) and sleep disturbances were significantly associated. There was no significant association between physical activity levels and sleep disturbances in Indonesian primary school students during the COVID-19 pandemic.
Characteristics of High-Risk Behaviours Related to Alcohol and Illicit Drug Use and their Associated Factors among Adolescents in Middle and High School Widjaja, Melanie; Latief, Abdul; Sekartini, Rini
Medicinus Vol 13, No 3 (2024): June
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v13i3.8883

Abstract

Background: Use of narcotics, psychotropic and addictive substances (NPA) in adolescents has become one of the major social problems we are facing in society and it gives a negative impact. This study was done to determine the characteristics and factors that influence high-risk behaviour of NPA use in adolescents in middle and high school, also introducing CRAFFT questionnaire as an early screening tool for alcohol an illicit drugs use.Methods: Quantitative study (validated questionnaire) was conducted among 514 subjects aged 12-18 years old. CRAFFT questionnaire was used to detect a high-risk behavior of alcohol and illicit drugs use and self-reported questionnaire used to determine the risk factors of NPA.Result: Most participants (19,6%) were involved in high-risk behaviour of alcohol and illicit drugs, with the majority was males (12,4%). This study showed smoking behaviour (23,8%), drinking alcohol (15,8%) and illicit drugs use (13,6%). The type of drugs being used were cannabis (52,7%), tramadol (15,2%), dextromethorphan (10,7%) and methamphetamine (6,3%). CRAFFT questionnaire has a good internal consistency with Cronbach’s α 0,73. Education level, authoritarian parenting style, unharmonious parents, peer pressure or threat, and extracurricular activities were factors that influenced high-risk behavior of alcohol and illicit drug useConclusions: Early detection, comprehensive treatment, and intervention of risk factors of NPA use are needed. CRAFFT can be use as one of the screening tools for detection of alcohol and illicit drugs use in adolescents.
Association Between Sensory Profile and Daily Functioning in Children with Autism Anindya, Isti; Soebandrio, Amin; Ariyanto, Ibnu Agus; Sekartini, Rini; Wiguna, Tjhin; Sari, Novika Purnama
Proceedings of the International Conference on Nursing and Health Sciences Vol 5 No 1 (2024): January-June 2024
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/picnhs.v5i1.2787

Abstract

In the diagnostic criteria outlined in the DSM-5-TR (APA, 2022) Autism is characterized by hyper- or hyporeactivity to sensory input or unusual interest. Children with Autism encounter challenges in processing sensory information, leading to difficulties in regulating responses to specific sensations and stimuli. Meanwhile, behaviours such as repetitive motor movements, running, aggression, and self-harming have been correlated with sensory processing disorders. Furthermore, some daily functioning that are often disrupted due to sensory processing disorders are sleeping, eating, and social activities. Therefore in this study, we aim to examine association between sensory profile and daily functioning in children with Autism. We collected data from parents of children aged 2-5 years with Autism (N = 96) and non Autism (N = 94) in Indonesia for three months (September-December 2023). Parents filled out five types of instruments (CARS-P, FISH, BAMBI, SCQ, and SSP) and sociodemographic data. The results of this study showed a significant difference between autistic and non-autistic groups in their daily functioning (p < 0.001). In autistic group, we found a significant relationship between sensory profiles and eating behavior (p < 0.001); and social communication skills (p < 0.001). In the non-autistic group, only sensory profile was corelated to eating behavior (p < 0.001). Primary results indicate that, the sensory profile is closely related to eating behavior and social communication skills in autistic children.
Characteristics of High-Risk Behaviours Related to Alcohol and Illicit Drug Use and their Associated Factors among Adolescents in Middle and High School Widjaja, Melanie; Latief, Abdul; Sekartini, Rini
Medicinus Vol. 13 No. 3 (2024): June
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v13i3.8883

Abstract

Background: Use of narcotics, psychotropic and addictive substances (NPA) in adolescents has become one of the major social problems we are facing in society and it gives a negative impact. This study was done to determine the characteristics and factors that influence high-risk behaviour of NPA use in adolescents in middle and high school, also introducing CRAFFT questionnaire as an early screening tool for alcohol an illicit drugs use.Methods: Quantitative study (validated questionnaire) was conducted among 514 subjects aged 12-18 years old. CRAFFT questionnaire was used to detect a high-risk behavior of alcohol and illicit drugs use and self-reported questionnaire used to determine the risk factors of NPA.Result: Most participants (19,6%) were involved in high-risk behaviour of alcohol and illicit drugs, with the majority was males (12,4%). This study showed smoking behaviour (23,8%), drinking alcohol (15,8%) and illicit drugs use (13,6%). The type of drugs being used were cannabis (52,7%), tramadol (15,2%), dextromethorphan (10,7%) and methamphetamine (6,3%). CRAFFT questionnaire has a good internal consistency with Cronbach’s α 0,73. Education level, authoritarian parenting style, unharmonious parents, peer pressure or threat, and extracurricular activities were factors that influenced high-risk behavior of alcohol and illicit drug useConclusions: Early detection, comprehensive treatment, and intervention of risk factors of NPA use are needed. CRAFFT can be use as one of the screening tools for detection of alcohol and illicit drugs use in adolescents.
Mental health problems in children with chronic disease at the pediatric inpatient ward of Dr. Cipto Mangunkusumo Hospital Wangke, Lydia; Medise, Bernie Endyarni; Wirahmadi, Angga; Sekartini, Rini; Gunardi, Hartono; Soedjatmiko, Soedjatmiko
Paediatrica Indonesiana Vol. 65 No. 1 (2025): January 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi65.1.2025.37-41

Abstract

Background Since the survival of a patient with chronic physical illness has improved, major concerns arise about their quality of life and functioning. Childhood and adolescence are critical periods for promoting mental health because more than half of mental health problems begin at this stage, and many of those mental health problems will persist into adult life. Objective To analyze the risk of mental health problems among children hospitalized with chronic disease. Method An analytic observational study with a cross-sectional design was conducted using secondary data of 754 children aged 4-18 years admitted to the pediatric inpatient ward of Cipto Mangunkusumo Hospital, Jakarta between June 2021 and August 2022. We collected the results of subjects’ mental health screening conducted by the Growth, Development, and Social Pediatrics Division, Department of Child Health, Cipto Mangunkusumo Hospital during the subjects’ admission. Mental health problems evaluated in this study included psychosocial dysfunction screened using the Pediatric Symptom Checklist 17 (PSC-17) and depression screened using the Children’s Depression Inventory (CDI). Results Of the 754 subjects included, 520 (69.0%) were classified as having a chronic disease. The prevalence of psychosocial dysfunction and depression in children with chronic diseases was 19.6% and 6.3%, respectively. Gender, nutritional status, and height had no significant association with psychosocial dysfunction and depression in children. Children with chronic disease were more likely to develop psychosocial dysfunction (OR 2.13; 95%CI 1.31 to 3.59; P<0.001) and depression (OR 2.57; 95%CI 1.04 to 7.62; P<0.03) compared with those who did not have chronic disease. Conclusion Children with chronic disease were more likely to develop psychosocial dysfunction and depression compared to those without a chronic disease. These results highlight the importance of mental health support in pediatric patients with chronic disease.
The mTOR and total protein levels of stunted children Andreinie, Ria; Mudjihartini, Ninik; Chandra, Dian Novita; Sekartini, Rini
Paediatrica Indonesiana Vol. 65 No. 1 (2025): January 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi65.1.2025.26-36

Abstract

Background Malnutrition is still a major health problem for children, with stunting being one of its manifestations. Human growth is in part controlled by the mammalian target of rapamycin (mTOR) pathway. Studies reviewing mTOR level and growth disorders in children are still limited and no research has described mTOR levels in stunted children in Indonesia. Objective To assess for a relationship between mTOR and total protein levels in blood plasma in stunted children aged 6-24 months and compare these levels with those in non-stunted children. Methods This case-control study was conducted in South Sumatra Province, Indonesia. Subjects were children aged 6-24 months. The inclusion criteria for the case group are children who have a length-for-age of <-2SD and the control group are children who have a body length according to age of more than or equal to -2 SD from the WHO growth standard chart. Anthropometric measurements were plotted on the WHO Growth Standards chart, while mTOR and total protein levels were measured using an ELISA method and spectrophotometry, respectively. Results Of 142 subjects, 71 children were allocated into each case and control group. Child characteristics that were significantly different between the two groups were age (P=0.002), birth length (P=0.012), weight-for-age Z-score (WAZ) (P<0.001), and body mass index (BMI) (P=0.015). WAZ status with the categories underweight and severely underweight had a higher risk of stunting. The mTOR and total protein levels between the two groups were not significantly different. Conclusion Further research is needed to explain the mechanism of mTOR signal deviations in children's growth and development, as mTOR and protein levels are not significantly different in stunted and non-stunted children.
Safety and immunogenicity of the CoV2-Bio in a healthy population aged 18 years and older in Indonesia Maria, Suzy; Olfriani, Ciho; Koesnoe, Sukamto; Sekartini, Rini; Soedjatmiko; Medise, Bernie Endyarni; Yuniar, Irene; Indawati, Wahyuni; Wirahmadi, Angga; Sari, Rini Mulia; Adi, Nuri Purwito; Retnaningdyah, Windri
Medical Journal of Indonesia Vol. 34 No. 1 (2025): March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.247476

Abstract

BACKGROUND According to the WHO Target Product Profiles for COVID-19 Vaccines, vaccine development should be indicated for active immunization in all populations, in conjunction with other control measures to curtail the pandemic. Several RBD-based COVID-19 vaccines are being evaluated and have shown advantages. CoV2-Bio was developed based on the wild-type SARS-CoV-2 RBD amino acid sequence, representing residues of the spike protein of the Wuhan-Hu-1 isolate. This study aimed to evaluate the safety and immunogenicity of CoV2-Bio when compared to CoronaVac. METHODS This was an observer-blinded, randomized controlled prospective study of safety and immunogenicity of the CoV2-Bio in healthy adult population. A total of 54 healthy participants were randomized to receive either 3 doses of CoV2-Bio or 2 doses of CoronaVac, and 1 dose of placebo, administered 28 days apart. Participants were followed up for safety and immunogenicity. IgG antibody titers (ELISA) and neutralization assay against Wuhan and Delta strains were evaluated at baseline, Days 28, 56, and 84. We assessed seropositive rate, seroconversion, and GMT as parameters. RESULTS Both vaccines were well tolerated and induced good antibody response. The incidence rate and intensity of local and systemic adverse events did not differ between vaccine and control groups. The vaccine group showed a larger proportion of seroconversion (4-fold increase antibody) (87.5% versus 46.2%, p = 0.001) and higher GMT (305.9 AU/ml versus 102.4 AU/ml, p<0.001) when compared to control group. CONCLUSIONS 3 doses of the CoV2-Bio are safe and immunogenic in healthy adult population. 3 doses of the CoV2-Bio COVID-19 vaccine produce a better immunogenicity profile compared to CoronaVac.
Association of eating behavior and diet quality among students in Taruna Nusantara Senior High School, Indonesia Triatmoko, Barkah; Chandra, Dian Novita; Khusun, Helda; Pramesthi, Indriya Laras; Sekartini, Rini
World Nutrition Journal Vol. 9 No. i1 (2025): Volume 09 Issue 1, August 2025
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V09.i1.0009

Abstract

Background: Poor adolescent diet quality is influenced by family eating habits, media promoting unhealthy foods, and body image pressures, leading to disordered eating, neglect of health considerations, and obesity. Even in controlled environments like boarding schools. Objective: This study aims to assess association between eating behavior and dietary quality among students in Taruna Nusantara Senior High School (TN-SHS), Indonesia. Methods: A cross-sectional study with 200 subjects aged 15-18 was conducted in January 2024. Participants were purposively sampled from TN-SHS boarding school. Data was collected using the Dutch Eating Behavior Questionnaire (DEBQ) and Diet Quality Index International (DQI-I), along with sociodemographic information, nutritional status, and physical activity. Analysis was performed using SPSS 29, employing multiple linear regression to examine the relationship between eating behaviors and diet quality. Results: There was strong relationship between eating behavior and diet quality on different days, revealing that restrained eating correlates with better diet quality on average days (r=0.158, p=0.026), while external eating is linked to poorer diet quality. The association between eating behavior and diet quality on weekdays is weaker than on weekends. External eating consistently reduces diet quality across all periods (β=–1.380 to –1.854, p<0.01). Males exhibiting lower diet quality (β=–3.021 to –4.904, p≤0.002) and higher pocket money associated with improved diet quality, particularly on weekends (β=–3.633, p=0.021). Conclusion: The study findings highlight the importance of managing external eating behaviors such as emotional eating, social eating, mindless eating, and binge eating, and suggest avenues for targeted interventions to promote healthier dietary habits.
Nutrient Intake Profile Among Children Aged 6–24 Months in Indonesia: A Descriptive Analysis Nurdina, Nazlah; Chandra, Dian Novita; Mudjihartini, Ninik; Sekartini, Rini
World Nutrition Journal Vol. 9 No. S1 (2025): Vol. 9 No. S1 (2025): Selected conference proceedings of the Nutri Symposium 2
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V09.S1.0024

Abstract

Background: Adequate nutrient intake in early childhood is critical for growth, cognitive development, and immune function. The first two years of life are a sensitive period where nutritional deficiencies may lead to long-term consequences. However, many children in low- and middle-income countries fail to meet dietary needs due to limited diversity and poor feeding practices. Objectives: To describe the intake of energy, macronutrients, and key micronutrients among Indonesian children aged 6–24 months
KUALITAS TIDUR PADA BAYI USIA 6-9 BULAN DI JAKARTA Herwanto, Herwanto; Sekartini, Rini; Batubara, Jose; Yusra; Kekalih, Aria; Lestari, Hesti; Andraini, Trinovita
Jurnal Muara Medika dan Psikologi Klinis Vol. 5 No. 1 (2025): Jurnal Muara Medika dan Psikologi Klinis
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Tarumanagara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24912/jmmpk.v5i1.35276

Abstract

Gangguan tidur dapat memengaruhi kondisi kesehatan seorang bayi. Penelitian ini bertujuan menganalisis faktor yang memengaruhi kualitas tidur bayi usia 6-9 bulan di Jakarta dengan menggunakan kuesioner Brief Infant Sleep Questionnaire-Revised (BISQ-R). Penelitian ini menggunakan desain studi potong lintang dengan pendekatan deskriptif analitik, data didapatkan melalui kuesioner BISQ-R untuk menilai kualitas tidur bayi berdasarkan pola tidur bayi, persepsi orang tua, dan kebiasaan pada orang tua yang terkait dengan tidur pada Bayi. Data dianalisis untuk mengidentifikasi faktor yang memengaruhi kualitas tidur bayi dan hubungan antar variabel. Sebanyak 88 subjek, yang terdiri dari 33 bayi perempuan dan 55 bayi laki-laki dengan rata-rata usia 7,76 bulan, terlibat dalam penelitian ini. Hasil penelitian menunjukkan mayoritas bayi memiliki kualitas tidur yang tergolong menengah serta menunjukkan bahwa faktor "jumlah waktu terbangun di malam hari" memiliki korelasi negatif yang signifikan terhadap kualitas tidur bayi (r = -0,258, p = 0,015), menunjukkan bahwa semakin sering bayi terbangun pada malam hari, semakin berkurang kualitas tidurnya. Kebiasaan orangtua merespons kebutuhan tidur dan tempat tidur bayi juga turut memengaruhi kualitas tidur. Penelitian ini menunjukkan pentingnya mengurangi frekuensi bayi terbangun di malam hari untuk meningkatkan kualitas tidurnya serta perlunya menjaga konsistensi rutinitas tidur dan menciptakan lingkungan tidur yang mendukung guna memastikan kualitas tidur bayi yang optimal.
Co-Authors Abdul Latief Aditya, Clarissa J. Amin Soebandrio Anindya, Isti Aria Kekalih Ariyanto, Ibnu Agus Armeilia, Rilie Batubara, Jose Bernie Endyarni Medise Chandra, Dian Novita Darmawan, Anthony C. Dian Kusumadewi Fathan, Fariz Dwi Gunawan, Talitha Dinda Hartono Gunardi Helda Khusun Herwanto Herwanto Hesti Lestari Irene Yuniar, Irene Maria, Suzy Medise, Bernie E. Mirtha, Listya T. Nadya, Ruth Ninik Mudjihartini Nurdina, Nazlah Nuri Purwito Adi Olfriani, Ciho Pramesthi, Indriya Laras Prastya, Reza Wahyu Dwi Retnaningdyah, Windri Ria Andreinie Rini Mulia Sari Saptawati Bardosono Sari, Novika Purnama Soedjatmiko Soedjatmiko Soedjatmiko Sukamto Koesnoe Tjhin Wiguna Triatmoko, Barkah Trinovita Andraini Tutik Ernawati Wahyuni Indawati, Wahyuni Wangke, Lydia Widjaja, Melanie Wirahmadi, Angga Yusra