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Pemanfaatan Nano Patch Peppermint Terhadap Hormon Kortisol Saliva dan Skala Nyeri Disminore Pada Remaja Yuni Nidaul Khasanah; Ari Suwondo; Sri Wahyuni
MAHESA : Malahayati Health Student Journal Vol 6, No 7 (2026): Volume 6 Nomor 7 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i7.23955

Abstract

ABSTRACT Dysmenorrhea is a common complaint among adolescents and can trigger increased uterine contractions and elevated cortisol levels. Peppermint has analgesic, antispasmodic, and anti-inflammatory effects, particularly when formulated as a nano patch, which enhances skin absorption. This study aimed to determine the effect of peppermint nano patches on reducing cortisol levels and alleviating dysmenorrhea in adolescents.A quasi-experimental design with intervention and control groups was used. The intervention group received the peppermint nano patch during menstruation. Variables measured included pain intensity using a numerical rating scale and salivary cortisol levels assessed via ELISA. Data were analyzed using paired t-tests and independent t-tests.The results showed that the mean pain intensity in the intervention group decreased from 7.40 to 3.65 (p = 0.000), while in the control group it decreased from 6.40 to 6.00 (p = 0.000). The difference between groups was significant (p = 0.000) with a large effect size (d = 1.91). Salivary cortisol levels in the intervention group decreased from 17.02 to 15.84 ng/ml (p = 0.001), whereas in the control group it changed only from 11.08 to 11.00 ng/ml. The difference between groups was significant (p = 0.042) with a moderate effect size (d = 0.42).The peppermint nano patch was effective in reducing pain intensity and salivary cortisol levels. This intervention can be considered a non-pharmacological alternative for alleviating menstrual complaints in adolescents. Keywords: Peppermint Nano Patch, Salivary Cortisol, Dysmenorrhea, Menstrual Pain, Adolescents.  ABSTRAK Dismenore merupakan keluhan yang sering dialami remaja dan dapat memicu peningkatan kontraksi uterus serta kadar hormon kortisol. Peppermint memiliki efek analgesik, antispasmodik, dan antiinflamasi, terutama ketika diformulasikan dalam bentuk nano patch yang meningkatkan absorpsi kulit. Penelitian ini bertujuan untuk mengetahui pengaruh nanopatch peppermint dalam menurunkan hormon kortisol dan menurunkan disminore pada remaja.Penelitian menggunakan desain quasi experiment dengan kelompok intervensi dan kontrol. Kelompok intervensi diberikan Nano Patch Peppermint selama menstruasi. Variabel yang diukur meliputi intensitas nyeri menggunakan skala numerik dan kadar hormon kortisol saliva melalui pemeriksaan ELISA. Analisis data menggunakan paired t-testdan independent t-test. Hasil penelitia rerata intensitas nyeri pada kelompok intervensi menurun dari 7,40 menjadi 3,65 (p=0,000), sedangkan pada kontrol dari 6,40 menjadi 6,00 (p=0,000). Perbedaan antar kelompok signifikan (p=0,000) dengan effect size besar (d=1,91). Kadar kortisol saliva pada kelompok intervensi turun dari 17,02 menjadi 15,84 ng/ml (p=0,001), sedangkan pada kontrol hanya dari 11,08 menjadi 11,00 ng/ml. Perbedaan antar kelompok signifikan (p=0,042) dengan effect size sedang (d=0,42). Nano Patch Peppermint efektif menurunkan nyeri dan kortisol saliva. Nano Patch Peppermint terbukti efektif menurunkan intensitas nyeri dismenore dan kadar hormon kortisol saliva pada remaja. Intervensi ini dapat menjadi alternatif nonfarmakologis dalam mengurangi keluhan menstruasi. Kata Kunci: Nano Patch Peppermint, Kortisol Saliva, Dismenore, Nyeri Haid, Remaja.
A Web-Based Information System for Supervising Students’ Final Projects and Scientific Papers Dr. drg. Supriyana , M.Pd.; Bambang Sutomo; Setya Wijayanta; Esti Handayani; Sri Wahyuni; Waris Agung Widodo
Jurnal Kesehatan Gigi Vol. 13 No. 1 (2026): June 2026
Publisher : Jurusan Kesehatan Gigi, Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkg.v13i1.14383

Abstract

Conventional final-project supervision in higher education is often ineffective, poorly documented, and difficult to monitor in real time. This study aimed to develop SIBIMA, a web-based information system for final-project supervision that supports communication, documentation, and monitoring of student supervision activities. This research used a Research and Development approach with the Waterfall model, consisting of needs analysis, system design, implementation, and testing. Functional testing was conducted using black-box testing, while the user interface and user experience were evaluated by 62 respondents, including program administrators, supervisors, and heads of study programs. The developed system facilitated title submission, supervision, revision documentation, scheduling, and structured monitoring of final-project progress. The evaluation indicated that the system functioned as intended and was well received by users across the main supervision workflows. SIBIMA has strong potential as a digital solution for improving the effectiveness of communication, supervision documentation, and monitoring of final-project preparation.