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All Journal Nexus Biomedika AKSONA
Riani Dwi Hastuti
Faculty of Medicine, Sebelas Maret University
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Neuroscience

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Perbedaan Kadar Caffeic Acid Phenethyl Ester antara Propolis yang Diekstraksi dengan Etanol dan Air Hastuti, Riani Dwi; HP, Diding; Hartati, Sri
Nexus Biomedika Vol 2, No 2 (2013): Nexus Biomedika
Publisher : Nexus Biomedika

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (13.862 KB)

Abstract

Background: Propolis  is a natural product derived from plant resins which is collected by honeybees. One of the major components of propolis is Caffeic Acid Phenethyl Ester (CAPE). The use of various kinds of solvents in propolis extraction effects CAPE level. The aim of this research was to know the difference levels of CAPE in ethanol extract propolis and water extract propolis. Methods: This study was experimental research with post test only group design. Samples were raw propolis taken from bee farm in Gejen RT 03 RW 02, Kerjo, Karanganyar. Samples were extracted with maceration method using ethanol and water as solvents. Both of ethanol extract propolis and water extract propolis were divided into five samples. CAPE levels were determined by UV Vis spectrophotometer at wave length of 700 nm using Prussian Blue method. Data were analyzed using independent sample t test. Results: The result showed that the average of CAPE level in propolis extracted with ethanol was 12.26 ± 0.658 µg/mL, while the average of CAPE level in propolis extracted with water was 5.564 ± 0.332 µg/mL. Conclusions: There was no significant difference between propolis extracted with ethanol and water. Keywords: CAPE, ethanol extract propolis, water extract propolis.
Incidence of Stroke Cases at Blambangan General Hospital of Banyuwangi in January-December 2022: A Descriptive Study Hastuti, Riani Dwi; Setyawan, Andar; Handayani, Indah Ari; Khalisha, Putri Nabila
AKSONA Vol. 4 No. 1 (2024): JANUARY 2024
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/aksona.v4i1.47492

Abstract

Highlight: The majority of stroke cases at Blambangan General Hospital in Banyuwangi are ischemic strokes. The age group that experienced the most strokes was >40 years. The gender that experienced the most strokes was female.   ABSTRACT Introduction: Stroke is a leading cause of morbidity in Indonesia. It significantly contributes to the overall burden of disease and places a substantial impact on the health of the population in Indonesia. Objective: The purpose of this study was to show the incidence of stroke cases in the Blambangan General Hospital in Banyuwangi. Understanding the prevalence of strokes at this particular hospital is critical for identifying patterns, improving patient care, and taking preventive actions to deal with this important health issue. Methods: This study used a retrospective cross-sectional sampling method to look at all 342 inpatient stroke cases that were treated in the neurology department of Blambangan General Hospital in Banyuwangi in 2022. All of their data was collected and analyzed. Results: Most cases of stroke in this study were ischemic strokes, with a total of 212 cases (62.0% of all cases). The age group that experienced the most strokes was over 40 years old (96.2%) and female (56.4%). More than half of stroke patients had hypertension, and 80.1% had diabetes mellitus. Conclusion: This study found that ischemic stroke survivors, mostly female and aged over 40, were frequently associated with diabetes mellitus and hypertension. These findings provide insights into the frequency of these stroke types within the examined population.  
Co-Authors Diding HP Handayani, Indah Ari Khalisha, Putri Nabila Setyawan, Andar Sri Hartati