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All Journal Jurnal Kesehatan Andalas Jurnal EduHealth
Arini Ghaisa Atsari
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Health Professions Public Health Veterinary

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Pengaruh Bevacizumab Intravitreal terhadap Best Corrected Visual Acuity dan Central Macular Thickness pada Diabetic Macular Edema Arini Ghaisa Atsari; Weni Helvinda
Jurnal Kesehatan Andalas Vol 8, No 4 (2019): Online December 2019
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v8i4.1094

Abstract

Diabetic Macular Edema (DME) adalah penyebab utama kebutaan pada populasi diabetes. Salah satu patogenesis pada DME adalah karena peningkatan ekspresi VEGF. Bevacizumab adalah anti-VEGF yang dapat meningkatkan Best Corrected Visual Acuity (BCVA) dan mengurangi Central Macular Thickness (CMT) pada pasien DME. Tujuan: Mengetahui persentase jenis kelamin, usia, durasi DM tipe II, BCVA dan CMT sebelum dan setelah injeksi pada bulan pertama dan bulan ketiga pada pasien DME serta menganalisis pengaruh intravitreal bevacizumab anti-VEGF terhadap BCVA dan CMT pada DME di Rumah Sakit M Djamil Padang. Metode: Penelitian ini adalah studi retrospektif analitik berdasarkan rekam medis dari 16 pasien DME yang telah injeksi bevacizumab intravitreal pada tahun 2017. Data dianalisis secara statistik menggunakan uji one way Anova dengan p < 0,05 dianggap signifikan. Hasil: Pasien terdiri dari 11 wanita (68,8%) dan 5 pria (31,2%). Jumlah usia pasien terbanyak antara 51-55 tahun (43,8%) dan durasi terlama yang diketahui DM tipe II adalah 5-10 tahun (50,0%). Rata-rata BCVA (logMAR) sebelum injeksi intravitreal bevacizumab adalah 0,95, bulan pertama setelah injeksi adalah 0,68, dan bulan ketiga setelah injeksi adalah 0,55. CMT rata-rata sebelum injeksi bevacizumab intravitreal adalah 427,62, bulan pertama setelah injeksi 359,59, dan bulan ketiga setelah injeksi 318,12. Simpulan: Terdapat pengaruh bevacizumab anti-VEGF intravitreal terhadap BCVA dan CMT di DME di Rumah Sakit M Djamil Padang.
Comparasion Of Visual Outcomes Post Small Incision Cataract Surgery With Phacoemulsification At Dustira Hospital 2017-2022 Lukmana Lokarjana; Arini Ghaisa Atsari; Natashya Iasha Bahtiar
Jurnal EduHealth Vol. 16 No. 01 (2025): Jurnal EduHealt, Edition January - March, 2025
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The eye is a human visual instrument that functions to provide information visually to the brain. One of the vision disorders that often occurs is cataracts. Global data on visual impairment in 2010 stated that cataracts are one of the most common visual impairment disorders worldwide (33%). Based on Riskesdas in 2018, the prevalence rate of cataracts in Indonesia is 1.5%. Treatment of eyes diagnosed with cataracts can be done with several surgical techniques including SICS and phacoemulsification. The purpose of this research is to determine the comparison of visual outcomes post surgery small incision cataract surgery with phacoemulsification at Dustira Hospital in 2017-2022. This research is an analytical descriptive research using retrospective cross sectional design. The sample of this study was patients diagnosed with cataracts who underwent surgery using SICS techniques and phacoemulsification in 2017-2022 at the Eye Poly of Dustira Hospital. The selection of research samples uses total sampling methods and those in accordance with the inclusion criteria and exclusion criteria that have been determined. The data were analyzed using Man Whitney's non-parametric hypothesis test. The results of this study obtained the results of visual examination of post-cataract surgery outcomes on the SICS technique and phacoemulsification techniques had p-values on the control day 1 p = 0.019, day 7 p = 0.008 and day 30 p = 0.046. So it can be concluded that there is a significant difference in visual outcomes after cataract surgery using the SICS technique with phacoemulsification at Dustira Hospital in 2017-2022.
Co-Authors Andrini Ariesti Lukmana Lokarjana Natashya Iasha Bahtiar Weni Helvinda