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All Journal Jurnal Kesehatan Andalas Journal of International Surgery and Clinical Medicine
Rizki Meizikri
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Health Professions Medicine & Pharmacology

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Hubungan Kejadian Pneumonia Neonatus dengan Beberapa Faktor Risiko di RSUP Dr. M. Djamil Padang Periode 2010-2012 Rizki Meizikri; Finny Fitry Yani; Yusrawati Yusrawati
Jurnal Kesehatan Andalas Vol 5, No 3 (2016)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v5i3.585

Abstract

AbstrakPneumonia merupakan salah satu penyebab mortalitas utama pada neonatus. Bayi Berat Lahir Rendah (BBLR), kelahiran preterm, ketuban pecah dini (KPD), dan demam intrapartum merupakan faktor risiko yang dapat berpengaruh terhadap kejadian pneumonia neonatus. Tujuan penelitian ini adalah menentukan hubungan antara faktor risiko tersebut dengan kejadian pneumonia neonatus di RSUP M. Djamil. Penelitian ini bersifat analitik dengan desain cross-sectional dengan mengumpulkan data rekam medis pneumonia neonatus di RSUP M. Djamil Padang periode 2010 –  2012.  Kontrol diambil data neonatus yang dirawat dengan diagnosis selain pneumonia pada periode yang sama. Neonatus dengan diagnosis sindrom gawat nafas, sepsis, meningitis, asfiksia, dan aspirasi telah dieksklusi terlebih dahulu. Sejumlah 49 sampel yang memenuhi kriteria terdapat temuan; KPD sebanyak 22,4%, demam intrapartum 20,4%, BBLR 18,4%, dan kelahiran preterm 10,2%. Sebanyak 24 sampel tidak memiliki faktor risiko. Analisis bivariat chi-square menunjukkan bahwa BBLR (p=0,46), kelahiran preterm (p=0,372), KPD (p=0,616), dan demam intrapartum (p=0,083) tidak memiliki hubungan yang signifikan dengan kejadian pneumonia neonatus di RSUP M. Djamil periode 2010-2012.Kata kunci: pneumonia neonatus, BBLR, kelahiran preterm, KPD, demam intrapartum.  AbstractPneumonia is one of leading mortality causes among neonates. Low Birth Weight (LBW), preterm birth, Premature Rupture Of Membranes (PROM) and intrapartum maternal fever are known as risk factors that might contribute to neonatal pneumonia occurence. The objective of this study was to determine relationship  the risk factors  to  neonatal pneumonia in M. Djamil hospital. This analytic research with cross-sectional design compiled neonatal pneumonia data from 2010-2012 medical record M. Djamil hospital. Controls were taken from neonates hospitalized in M. Djamil within the same period. Neonates with respiratory distress syndrome, sepsis, meningitis, asphyxia, and aspiration were excluded. The 49 subjects that meet research criteria, PROM were found in 22,4% of neonates,intrapartum fever 20,4%, LBW 18,4%, and preterm birth 10,2%. Twenty four of them do not have any of those risk factors. Bivariate analysis with chi-square shows that none of those risk factors are significantly related to neonatal pneumonia in M. Djamil hospital period 2010-2012 (LBW p=0,46; preterm birth p=0,372; PROM p=0,616; intrapartum fever p=0,083).Keywords: neonatal pneumonia, LBW, preterm birth, PROM, intrapartum fever
Interaction of antifibrinolytic providing intrathecal in intraventricular blood: a systematic review and meta-analysis Fitra; Rizki Meizikri; Rafif Alfayat; Imam Hidayat; Wahyu Asrizal, Cynthia
Journal of International Surgery and Clinical Medicine Vol. 3 No. 1 (2023): (Available online: June 2023)
Publisher : Surgical Residency Program Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jiscm.v3i1.40

Abstract

Introduction: Intraventricular hemorrhage refers to the presence of blood in the cerebroventricular system.  Intraventricular hemorrhage can lead to severe complications such as hydrocephalus. One of the therapeutic modalities for intraventricular hemorrhage is to perform CSF diversion using an external ventricular drain (EVD). To overcome complications related to the use of EVD, there have been several efforts to accelerate its excretion in ventricular blood, one of which is by intraventricular injection of fibrinolytic. The mixed results of studies on intraventricular fibrinolysis prompted investigators to conduct a review and meta-analysis of this treatment modality. Method: We conducted systematic reviews and meta-analyses on several literature databases and included articles in English. We were using the boolean operator AND to search for literature containing all keywords in the databases and analyze the data using SPSS and Revmann. Results: Unfavorable outcomes with the use of intraventricular fibrinolytic therapy in IVH occurred in a median of 51% of cases. The risk of an unfavorable outcome in IVH patients who received intraventricular fibrinolytic was 0.93 times compared to controls. The risk of an unfavorable outcome in IVH patients receiving rtPA and intraventricular urokinase was 0.95 and 0.73 times, respectively, compared to controls. The use of intraventricular fibrinolysis was able to reduce IVH volume by an average of 22.84 cc. The use of intraventricular fibrinolysis was able to improve the modified Graeb Score with an average change of 5.24 points Conclusion: Intraventricular fibrinolysis administration helps to reduce the risk of unfavorable outcomes in IVH cases.
Co-Authors Finny Fitry Yani Fitra Rafif Alfayat Wahyu Asrizal, Cynthia Winnugroho Wiratman, Manfaluthy Hakim, Tiara Aninditha, Aru W. Sudoyo, Joedo Prihartono Yusrawati Yusrawati