Wahyu Asrizal, Cynthia
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Interaction of antifibrinolytic providing intrathecal in intraventricular blood: a systematic review and meta-analysis Fitra; Rizki Meizikri; Rafif Alfayat; Imam Hidayat; Wahyu Asrizal, Cynthia
Journal of International Surgery and Clinical Medicine Vol. 3 No. 1 (2023): (Available online: June 2023)
Publisher : Surgical Residency Program Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jiscm.v3i1.40

Abstract

Introduction: Intraventricular hemorrhage refers to the presence of blood in the cerebroventricular system.  Intraventricular hemorrhage can lead to severe complications such as hydrocephalus. One of the therapeutic modalities for intraventricular hemorrhage is to perform CSF diversion using an external ventricular drain (EVD). To overcome complications related to the use of EVD, there have been several efforts to accelerate its excretion in ventricular blood, one of which is by intraventricular injection of fibrinolytic. The mixed results of studies on intraventricular fibrinolysis prompted investigators to conduct a review and meta-analysis of this treatment modality. Method: We conducted systematic reviews and meta-analyses on several literature databases and included articles in English. We were using the boolean operator AND to search for literature containing all keywords in the databases and analyze the data using SPSS and Revmann. Results: Unfavorable outcomes with the use of intraventricular fibrinolytic therapy in IVH occurred in a median of 51% of cases. The risk of an unfavorable outcome in IVH patients who received intraventricular fibrinolytic was 0.93 times compared to controls. The risk of an unfavorable outcome in IVH patients receiving rtPA and intraventricular urokinase was 0.95 and 0.73 times, respectively, compared to controls. The use of intraventricular fibrinolysis was able to reduce IVH volume by an average of 22.84 cc. The use of intraventricular fibrinolysis was able to improve the modified Graeb Score with an average change of 5.24 points Conclusion: Intraventricular fibrinolysis administration helps to reduce the risk of unfavorable outcomes in IVH cases.
Risk Factors Computer Vision Syndrome in Computer Engineering Students, Syiah University of Kuala Indriyani, Fonna; Basri, Saiful; Wahyu Asrizal, Cynthia
Journal Research of Social Science, Economics, and Management Vol. 1 No. 9 (2022): Journal Research of Social Science, Economics, and Management
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jrssem.v1i9.159

Abstract

Computer Vision Syndrome (CVS) is a collection of symptoms related to computer use prolonged. This can occur from various factors consisting of individual factors, computer factors and environmental factors. Computer engineering students are a group of students who use computers in doing assignments and other activities in daily life. The purpose of this study was to determine the risk factors for CVS events in students of the Computer Engineering Study Program, Syiah Kuala University. This research is an observational analytic survey with a cross sectional. The sample used consisted of 164 students from the 2017-2019 class who were taken by the stratified random sampling method. Collecting data through self-assessment using a questionnaire. Statistical test using Chi square test for bivariate and to find out which risk factor is the most influential, multivariate analysis is used, namely logistic regression analysis. The results showed that 63.4% of Computer Engineering Students at Syiah Kuala University experienced CVS. The factors that were significantly associated with the incidence of CVS were gender (p=0.03), duration of computer use (p=0.01) and eye distance to the monitor (p=0.001).