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Masalah-Masalah terkait Pengobatan Diabetes Melitus Tipe 2: Sebuah Studi Kualitatif Retno Wahyuningrum; Djoko Wahyono; Mustofa Mustofa; Yayi S. Prabandari
Indonesian Journal of Clinical Pharmacy Vol 9, No 1 (2020)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/ijcp.2020.9.1.26

Abstract

Pengelolaan diabetes melitus tipe 2 (DMT2) yang kompleks memicu masalah-masalah yang menyebabkan sasaran terapi tidak tercapai. Tujuan penelitian ini adalah untuk mengidentifikasi masalah-masalah yang dialami pasien DMT2 dalam pengobatan. Pendekatan kualitatif digunakan dalam desain penelitian ini. Pengumpulan data melalui wawancara semiterstruktur, bertatap muka. Rekrutmen partisipan dilakukan di poliklinik penyakit dalam rumah sakit di Yogyakarta (RSUD Sleman, RS Bethesda, dan RSUD Wates) pada bulan November 2015–Mei 2016. Kombinasi pertanyaan terbuka dan tertutup diterapkan untuk memperoleh jawaban dari partisipan. Pertanyaan-pertanyaan wawancara terkait dengan pemahaman tentang penyakit dan obat, aktivitas perawatan diri diabetes, komunikasi dengan tenaga kesehatan, dukungan sosial, dan kondisi psikologis. Setiap sesi wawancara direkam audio, ditranskrip verbatim, dan dianalisis menggunakan matriks. Partisipan juga diperiksa kadar HbA1c untuk mengetahui baik-buruknya kontrol glikemik. Dua puluh tiga partisipan memenuhi sesi wawancara, berusia antara 35–72 tahun dan didominasi perempuan (n=12). Kadar HbA1c rata-rata 7,9±2,0 %. Hasil analisis data teridentifikasi masalah pasien DMT2 dikategorikan menjadi masalah terkait faktor demografi, sosial, gaya hidup, hubungan dengan tenaga kesehatan, pemahaman mengenai penyakit, efek penyakit, pengendalian penyakit, komorbiditas, pengetahuan tentang pengobatan, dan asupan obat. Pemberian edukasi dan konseling kefarmasian sebaiknya tidak hanya berorientasi pada terapi farmakologi saja, namun juga memberikan motivasi pada pasien untuk mengubah perilaku, serta mempertimbangkan faktor psikologis dalam pengelolaan DMT2. Kata kunci: Diabetes melitus, edukasi, konseling, masalah terkait pengobatan, wawancaraMedication-related Problems in Patients with Type 2 Diabetes Mellitus: A Qualitative StudyAbstractThe complexity of type 2 diabetes mellitus (T2DM) management offers plenty of challenges to patients. Poor glycaemic control, the presence of complications and comorbidities, and non-adherence furnish the challenges in arranging glycaemic target. This study was performed to explore the medication-related problems experienced by T2DM patients during treatment. Qualitative research was conducted through face-to-face semi-structured interviews. The combination of open- and closed-ended questions was formulated focusing on domains including illness- and medicine-related knowledge, diabetes self-care activities, patient–healthcare professional communication, social support, and psychological conditions. Interview sessions were audio-recorded, transcribed verbatim, and analyzed into matrix. Glycated hemoglobin (HbA1c) were measured to assess glycaemic control. Twenty-three T2DM outpatients from three general hospitals in Yogyakarta (Sleman District Hospital, Bethesda Hospital, and Wates District Hospital) were recruited and completed the protocol. The participants were 35–72 years old, was dominated by female (n=12), and had a mean HbA1c level 7.9 ± 2.0 %. Perceived factors leading medication therapy problems were of three types and related to: patient-, clinical condition-, and medicine-related factors. Patient-related factors were related to sociodemographic, lifestyle, and relationship with healthcare provider. Clinical condition-related factors included knowledge about illness, effects of illness, control over symptoms, comorbidities. Medicine-related factors associated with lack of knowledge about medicines and medicine use. This study concluded that behavior change and psychological well-being should be noticed when leading diabetes education and counseling.Keywords: Counseling, diabetes mellitus, education, interview, medication therapy problems
Pengaruh Pemberian Ekstrak Akar Pasak Bumi Terstandar terhadap Gambaran Histopatologik Testis dan Konsentrasi Testosteron pada Tikus FARIDA HAYATI; SITARINA WIDYARINI; LUKMAN HAKIM; NGATIDJAN NGATIDJAN; MUSTOFA MUSTOFA
JURNAL ILMU KEFARMASIAN INDONESIA Vol 10 No 1 (2012): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1918.329 KB)

Abstract

The root of pasak bumi (Eurycoma longifolia, Jack) is one of plant from Indonesia known as aphrodisiac. This study was conducted to evaluate the influence of pasak bumi standardized extract to testosterone level and histopathological changes of the testes in male Wistar rats. Sample were 50 adult male rats aged 3 4 months were divided into 5 groups. Group I (control) was given distilled water, group II (positive control), was given testosterone (Andriol ®), group III, IV, and V were each given a standardized extract of the roots of pasak bumi doses of 50, 100, and 200 mg/kg of body weight, respectively. The extract was given orally twice a day for six days and forty nine days and then testes was taken out on 7th and 50th day. Testosterone level was assayed on 7th and 50th day by the ELISA methods. The results were analyzed using one way ANOVA, and post hoc Dunnet (2-sided) (p < 0.05). The data of this study shows that treatment with water extract of pasak bumi root influence the number of Leydig cells that would also increase the concentration of testosterone in Wistar male rats positively at a dose of 100 mg/kg and 200 mg/kg body weight.
Evaluasi Hasil Edukasi Farmasis Pada Pasien Diabetes Melitus Tipe 2 Di Rumah Sakit Dr. Sardjito Yogyakarta SESILIA ANDRIANI KEBAN; LUTFAN BUDI PURNOMO; MUSTOFA MUSTOFA
JURNAL ILMU KEFARMASIAN INDONESIA Vol 11 No 1 (2013): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

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Abstract

Diabetes mellitus (DM) is a metabolic disorder caused by a defect in insulin secretion or insulin action. Number of diabetic patients will increase if strategies are not prepared for preventing and controlling diabetes. This study aimed to evaluate the outcome of pharmacist education on the level of knowledge, level of medication adherence and diet, as well as the A1C value of type 2 diabetic patients in Dr. Sardjito Hospital Yogyakarta. This research was conducted prospectively using Nonrandomized Concurrent Control Trial. The number of subjects recruited were based on a three-months period and subjects were taken by consecutive sampling method. There were two groups: one group received education intervention for 3 months, and the other group as control did not receive education. Data were analyzed descriptively and quantitatively using Independent T and T-Paired test. The results showed that patients in the control group have developed an increase in the level of knowledge and adherence by themself, on the other hand patients in this group showed a decrease in A1C values, but the decrease was not as big as patients in the intervention group. Patient’s adherence to diet did not improve in either control nor intervention group. It can be concluded that education given by pharmacist can increase knowledge and adherence towards medication and decrease the A1C values of DM type-2 patients.
Do education and religiosity affect redistribution preferences? Mustofa Mustofa; Catur Sugiyanto; Akhmad Akbar Susamto
Jurnal Cakrawala Pendidikan Vol 42, No 1 (2023): Cakrawala Pendidikan (February 2023)
Publisher : LPMPP Universitas Negeri Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21831/cp.v42i1.53109

Abstract

Redistribution preference refers to an individual's tendency or priority in dealing with redistribution problems. This study aims to examine the effects of education and religiosity on redistribution preferences. The novelty in this study is an estimation strategy that includes the influence of education and parental education. The data utilized WVS Wave 7 data. The data analysis used probit regression analysis with a sample of 66,468 respondents. The research results show that the higher the education is, the greater possibility of individual to agree with inequality income will be. Individuals who graduated from elementary and junior high schools tend to agree with equal income, while individuals who graduated from high school and college tend to agree with unequal income. The higher the mother's education is, the greater possibility of individuals to agree with equal income will be. The higher the father's education is, the greater possibility of individuals to agree with unequal income will be. Religiosity has a different influence on redistribution preferences. The obedience variable has a positive influence, while the variable of belief in places of worship and frequency of worship tend to have a negative influence.