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CACAO SEED (THEOBROMA CACAO L.) EXTRACT GEL EFFECT ON THE NEUTROFIL NUMBER AFTER TOOTH EXTRACTION Atik Kurniawati; Dwi Riski Saputra; Zainul Cholid; Hendito K. Putra
Odonto : Dental Journal Vol 7, No 1 (2020): July 2020
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (610.284 KB) | DOI: 10.30659/odj.7.1.60-67

Abstract

Analyzing the antibacterial ability of green okra fruit (Abelmoschus esculentus L. Moench.) extract at several concentrations against Staphylococcus aureus: an experiment study Lestari, Sri; Safitri, Rizkiya Agnes; Cholid, Zainul; Dharmayanti, Agustin Wulan Suci
Padjadjaran Journal of Dentistry Vol 35, No 2 (2023): July 2023
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol35no2.46281

Abstract

ABSTRACTIntroduction: The common bacteria found in infected root canals are Gram-positive bacteria such as Staphylococcus aureus (20%). The bacterial infection can spread to the periapical tissues causing periapical lesions. Pulp necrosis, the cause of periapical lesions, requires root canal treatment. Ethylenediaminetetraacetic acid (17% EDTA) is one of the irrigants that can be used for root canal treatment however, 17% EDTA has a low antibacterial effect. The green okra fruit extract contains antibacterial properties that can inhibit the growth of bacteria. This study aims to analyze the antibacterial ability of green okra fruit extract at concentrations of 12.5, 25, 50, and 100% against S. aureus using a negative and positive control. Methods: This type of research was an in-vitro laboratory experiment with a posttest-only control group design. The antibacterial test using the disc diffusion method consisted of six groups: green okra fruit extract concentrations of 12.5, 25, 50, 100, and 17% EDTA (positive control), and aquadest (negative control). Antibacterial ability is indicated by the clear zone produced around the disc paper. Results: The average diameters of the inhibition zone were the green okra fruit extract concentrations of 12.5% (12.14), 25% (14.89), 50% (18.53), 100 (21.1), and 17% EDTA (22.08 mm), and 0 mm for aquadest. The results were analyzed using the Mann-Whitney test and showed a significant difference between all research groups (p<0.05). Conclusion: The antibacterial ability of green okra fruit extract (Abelmoschus esculentus L. Moench) against S. aureus increased with increasing concentrations, but remained lower than the antibacterial ability of 17% EDTA.
The role of purple leaves extract (Graptophyllum Pictum (L.) Griff) on the number of fibroblasts and blood vessels in the socket after tooth extraction Kurniawati, Atik; Kristanti, Yuli Dwi; Rahmat, Naila Azifatur; Rahayu, Yani Corvianindya; Cholid, Zainul; Sosiawan, Agung
Dental Journal (Majalah Kedokteran Gigi) Vol. 57 No. 1 (2024): March
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v57.i1.p56-61

Abstract

Background: Tooth extraction is the process of removing teeth from the alveolus. It will leave a mark on the socket and surrounding soft tissue. One of the cells that plays an important role in the wound healing process after tooth extraction is fibroblasts. When an injury occurs, some blood vessels are damaged; therefore, new blood vessels need to form. Purple leaves extract could be an alternative treatment for wound healing after tooth extraction as it contains flavonoids, saponins, alkaloids, steroids, and tannins. Purpose: The study aimed to analyze the role of purple leaves extract on the increase in fibroblasts and blood vessels in the socket after tooth extraction in Wistar rats. Methods: The method used was a laboratory experiment with a post-test-only control group design. The samples used were 24 rats divided into two groups: the control group, which was given aquadest, and the treatment group, which was given 1.5 mL of purple leaves extract with 10% concentration by sondage. Tissue preparations were used to count fibroblasts, and blood vessels were counted and observed on the 3rd, 5th, and 7th days. Results: Statistical tests showed a significant difference in the number of fibroblasts and blood vessels between the control and treatment groups on days 3, 5, and 7. Conclusion: Purple leaves extract could increase the number of fibroblasts and blood vessels in the tooth socket after tooth extraction of Wistar rats.