Ishandono Dachlan
Plastic And Reconstructive Surgery, Department Of Surgery, Faculty Of Medicine, Public Health, And Nursing, Universitas Gadjah Mada, Universitas Gadjah Mada /Dr. Sardjito General Hospital, Yogyakarta

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Sepsis risk factor in mount Merapi eruption victims with 2nd or 3rd degree of burn injury Yamoguna Zega; Ishandono Dachlan
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 50, No 1 (2018)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (291.266 KB) | DOI: 10.19106/JMedSci005001201810

Abstract

Sepsis is one of the fatal complications of burns. It is the most common cause of deathfrom burns. Burn sepsis usually occurs after a burn injury develops into infection. Thisstudy was conducted to determine correlation between age, burn area, inhalation trauma,enteral nutrition start time, escarotomy time, and albumin level of sepsis in patientswith 2nd or 3rd degree burn injury. This was a cross sectional study during May to June2012. The subjects in this study were 39 victims of mount Merapi eruption in 2010 whosuffered 2nd or 3rd degree of burns injury. The result showed the correlation betweenwidespread burns, inhalation trauma, time of escarotomy, and albumin levels with sepsis(p < 0.05). In conclusion, the risk factor for sepsis in patients with 2nd or 3rd degree ofburns injury are the area of burns (> 50%), inhalation trauma, time of escarotomy (> 72hours), and albumin levels (<3.5g/dL).
Sumbing Median (Midline Cleft) Ishandono Dachlan; A. Yuda Handaya; Sagiran Sagiran
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 5, No 2 (2005)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v5i2.1872

Abstract

Midline Cleft is a midline deformity of the upper lip and nose (Tessier Clasification of Cleft Number 0 ). It is rare and often accompanied by disorder of the central nervous system. Head CT Scan with a better architecture of the brain has a better prognosis and those with poor differentiation of brain die during infancy. The treatment of choice is surgical procedure to correct the deformity by Z-plasty or its modification. The aim of this stydy is to report the management of a midline cleftTwo Cases has been reported, The first case was a 13 year-old girl suffering from a midline upper lip cleft, she visited to Sardjito Hospital because of a cosmetic problem, and she had a good achievements at School, The head CT Scan showed a normal brain architecture. She had undergone an upper lip modification Z- Plasty. The second case was a 2 day-old male baby within absence of collumella and prolabial segment of lip (false median cleft), absence of the premaxilla skeletal and he suffers multiple anomalies, the head CT scan showed poor differentiation of brain.Result of this study showed that the one case has showed a good result after upper lip modification of Z-Plasty, the second case died before treated any surgical operation. It can concluded that midline cleft should be treated with observing other problems or anomalies especially of the brain structure and followed with delicate method of surgical procedure.Sumbing median adalah kelainan median pada bibir atas dan hidung (Klasifikasi Tessier, Cleft Nomor 0). Sumbing median adalah kelainan yang jarang terjadi dan biasanya disertai dengan gangguan sistem syaraf pusat. CT Scan kepala yang menunjukkan struktur otak baik mempunyai prognosis lebih baik, Gambaran struktur otak yang jelek biasanya meninggal pada awal kehidupan atau masa pertumbuhan. Terapi pilihan biasanya berupa prosedur pembedahan untuk mengoreksi kelainan, dengan teknik Z-plasty atau modifikasinya. Tujuan dari kajian ini adalah untuk melaporkan penatalaksanaan dua buah kasus sumbing median.Delaporkan dua kasus sumbing median, kasus pertama wanita usia 13 tahun menderita sumbing pada pertengahan bibir atas, pasien datang ke Rumah sakit Sardjito dengan keluhan kosmetik, pasien mempunyai prestasi yang baik di sekolah. CT Scan kepala menunjukan gambaran otak normal. Pasien dilakukan operasi Z- Plasty pada bibir atas. Kasus ke dua,pasien laki-laki usia 2 hari dengan tidak adanya collumella danprolabial, serta tidak adanya tulang premaxilla, pasien menderita anomali multipel, CT Scan kepala menunjukan gambaran otak yang tidak sempurna.Kasus pertama menunjukan hasil yang baik setelah dilakukan operasi Z-Plasty, kasus kedua meninggal sebelum dilakukan tindakan bedah. Oleh karena itu dapat disimpulkan bahwa penatalaksanaan sumbing median harus memperhatikan anomali lain terutama struktur otak dan perlu mempertimbangkan teknik operasi yang tepat untuk mendapatkan hasil yang baik.
Comparison of Applications of Aloe Vera, Honey, Saliva, and Ovalbumin on Collagen Formation in Wound Healing of Incised Skin in Rats R. Wahyu Kartiko Tomo; Ishandono Dachlan; Dewajani Dewajani
Academic Hospital Journal Vol 1, No 1 (2018): March
Publisher : Rumah Sakit Akademik Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ahj.v1i1.33620

Abstract

Background: Aloe vera, honey, human saliva, and ovalbumin are useful in the wound healing process. Collagen acts as an indicator of wound healing.Objective: This research aimed to compare the effect of Aloe vera, honey, human saliva and ovalbumin on collagen formation in wound healing.Design: This research was a laboratory experimental study on sixty white rats (Rattus novergicus) which were divided into 5 groups. Four groups were cases with skin applications and 1 group was controls with NaCl. We performed general anesthesia procedure, making an incision on skin of back, then the wound was sutured, and on surface of the sutured wound we applied substrate twice a day for six days. On day four and seven, after euthanasia, the sutures were removed, and the incised skin was taken for histological examination. We counted and analyzed the size of collagen with Image Raster tool programs. Data were analyzed with t-test, Mann Whitney, ANOVA and Kruskal Wallis tests, and then with post hoc tests.Results: After day four, the mean area of collagen of Aloe vera group was 55391.19 ± 30939.63, honey 24194.88 ± 43700.39, saliva 25869.86 ± 31608.39, ovalbumin 82459.19 ± 80994.66, NaCl  97658.04 ± 88452.74, with no significant differences between collagen sizes with p=0.125 (˃0.05). Decapitation day seven, significant differences with p=0.017 (˂0.05), in honey group 18601.67 ± 29260.28 and saliva 17560.31 ± 27262.03 than the control NaCl  94126.22 ± 29500.27.Conclusions: Collagen sizes after day four among the groups of Aloe vera, honey, saliva, ovalbumin and saline did not differ significantly. Collagen sizes after day seven of honey and saliva groups were significantly different than the controls.
THE USE OF AMNIOTIC MEMBRANE FOR WOUND HEALING IN BURN INJURIES Prawoto, Almas Nur; Ishandono Dachlan
Jurnal Rekonstruksi dan Estetik Vol. 7 No. 2 (2022): Jurnal Rekonstruksi dan Estetik, December 2022
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jre.v7i2.36050

Abstract

HIGHLIGHTS: 1. An organic bandage that can be helpful in the treatment of burn wounds is amniotic membrane. 2. The mechanisms of amniotic membrane for the treatment of burns and wounds should be investigated and understood in more detail.   ABSTRACT: Introduction: Burn injuries are associated with significant mortality and morbidity around theworld. The care of burn wounds requires a great amount of medical resources, therefore it is important to find a wound dressing that accelerates wound healing and is readily available. Methods: Literature search from online databases using relevant keywords about the usage of amniotic membranes in burn patients. Results: Research has shown that it contains antimicrobial properties that could be of great benefit in burn patients and is compatible to use in developing countries because it is readily available, easy to obtain and sterilize, able to cover wounds of large size, protects the wound from excessive water and electrolyte loss, reduces pain intensity, requires fewer dressing changes and is also more cost effective than conventional dressings. Conclusion: Amniotic membrane is a biological dressing that can be useful in the treatment of burn wounds. Further research should be conducted to investigate and understand the mechanisms of amniotic membrane for burn and wound care.