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All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Jurnal Rekonstruksi dan Estetik Indonesian Journal of Biomedicine and Clinical Sciences Folia Medica Indonesiana
Siti Isya Wahdini
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience

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Breast reconstruction with autologous tissue following mastectomy: two case reports of a delayed conventional transverse rectus abdominismyocutaneous (TRAM) and latissimus dorsi myocutaneous (LDM) flap surgery Seswandhana, Rosadi; Wicaksana, Aditya; Wahdini, Siti Isya; Dachlan, Ishandono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 50, No 4 (2018)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1504.075 KB) | DOI: 10.19106/JMedScie/005004201813

Abstract

Breast cancer is the most common malignant tumor and the leading cause of death among females. Most women with breast cancer will undergo breast-conserving surgery (BCS) or lumpectomy, simple or total mastectomy, modified radical mastectomy or bilateral mastectomy. Breast reconstruction solves many of the problems. The goal is to return the patient to a near-normal state so that she is not handicapped in her daily living. Breast reconstruction is also intended to offer psychological benefits to women treated by mastectomy following a diagnosis of possibly terminal cancer. In these case reports, we reported two successful cosmetic reconstruction cases. The first case was a 39-years-old female with non-recurrent breast cancer consulted and was referred by the oncology surgeon to the Plastic Reconstructive, and Aesthetic Surgery Division, Department of Surgery, Dr. Sardjito General Hospital. She wanted to undergo breast reconstruction. We planned to operate three years following mastectomy. She was diagnosed with 3B-stage of right breast cancer before. After the surgery, the patient received six series of chemotherapy. She also underwent radiotherapy 25 times and hormonal therapy. We decided to perform a transverse rectus abdominis myocutaneous (TRAM) flap surgery on her with 22 months follow up. The procedure provided good results, and the patient was satisfied. The second case was a 32-year-old woman who after excision of a phyllodes tumor and wanted breast reconstruction. Reconstruction was performed four years after tumor removal using latissimus dorsi myocutaneous (LDM) flap. The surgery provided good results, and the patient was satisfied. We reported two successful cosmetic reconstruction cases of non-recurrent 3B-stage of right breast cancer post-mastectomy after pedicled TRAM flap surgery and left breast post excision of phyllodes tumor after LDM flap surgery.
A rare case of syringocystadenoma papilliferum: clinical and histopathological insights Andayani, Raden Roro Rini; Pudjiati, Satiti Retno; Harsono, Erliana Tantri; Rizkiani, Dwinanda Almira; Hanggoro Tri Rinonce; Rita Cempaka; Indra Wahono; Siti Isya Wahdini; Dyah Ayu Mira Oktarina
Indonesian Journal of Biomedicine and Clinical Sciences Vol 57 No 3 (2025)
Publisher : Published by Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/inajbcs.v57i3.17146

Abstract

Syringocystadenoma papilliferum (SCAP) is a rare benign adnexal neoplasm originating from apocrine or eccrine sweat glands, first reported by Stokes in 1917. Clinically, SCAP manifests in various forms such as nodules, plaques, or warts, predominantly affecting the scalp in adolescents or children. Histopathologically, it is characterized by papillary and ductal invaginations lined with a two-layered epithelium. This condition can be present at birth or emerge during puberty. We present a 19-year-old female with a congenital, pinkish-brown, wart-like lesion on her scalp that progressively enlarged and spread to the face. Physical examination revealed a verrucous plaque with central erosion, extending from the temporal scalp to the lateral face. Dermoscopy showed papillary structures with defined lesion borders, while histopathological findings confirmed SCAP. The patient underwent surgical excision, and no new lesions were detected during a 3 mo follow-up. Syringocystadenoma papilliferum is often confused with other neoplasms such as sebaceous nevus or verruca vulgaris, but its definitive diagnosis relies on histopathology. The tumor’s characteristic features include cystic invaginations into the dermis with a two-layered epithelium, differentiating it from other conditions. Surgical excision remains the treatment of choice to prevent potential malignant transformation and improve cosmetic outcomes. Syringocystadenoma papilliferum, though rare, can be effectively managed through timely diagnosis and surgical excision. In this case, the patient’s postoperative outcome was favorable, with no recurrence of the lesion. Histopathological evaluation is crucial for accurate diagnosis and guiding treatment strategies.
RECURRENT TEMPOROMANDIBULAR JOINT ANKYLOSIS CAUSED BY OLD FRACTURE: A CASE REPORT Isya Wahdini, Siti; Idamatussilmi, Fina
Jurnal Rekonstruksi dan Estetik Vol. 10 No. 2 (2025): Jurnal Rekonstruksi dan Estetik, December 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jre.v10i2.66548

Abstract

Highlights: Adequate physiotherapy is essential to prevent the recurrence of temporomandibular joint ankylosis. Surgical treatment alone is insufficient without proper postoperative physiotherapy and patient compliance. Abstract Introduction: Temporomandibular joint (TMJ) ankylosis can greatly impact a child's nutrition, mental health, and craniofacial development. Trauma is the main cause. Early and proper treatment is crucial to avoid long-term issues and reoccurrence. Case Illustration:An 11-year-old girl presented with limited mouth opening and lower jaw pain three years after falling down the stairs. She underwent gradual TMJ distraction using bite blocks under general anesthesia followed by weekly physiotherapy, but her symptoms recurred after four months. A CT scan revealed left TMJ synarthrosis and condylar deformity. With improved adherence to physiotherapy, she achieved significant mouth opening and remained recurrence-free for six months.. Discussion: Gradual distraction with bite blocks, combined with regular physiotherapy, can improve joint mobility and muscle function while lowering the chances of re-ankylosis. This approach offers a less invasive option than surgery, which is especially valuable for children whose growth must be preserved. Closed procedures with structured rehabilitation are preferred because they result in fewer complications and require fewer follow-up appointments. Conclusion: The effectiveness of a non-invasive approach combining gradual distraction and physiotherapy in managing TMJ ankylosis is presented. The success of this treatment relies heavily on the patient's motivation and commitment. Early conservative treatment could be the main strategy for pediatric cases, potentially delaying or avoiding surgery. Continuous education and monitoring are key to achieving long-term success and preventing relapse.
Effect of platelet rich plasma (prp) to autogenous bone graft Saputro, Iswinarno Doso; Hutagalung, Magda Rosalina; Wahdini, Siti Isya
Folia Medica Indonesiana Vol. 53, No. 1
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Bone graft use in maxillofacial surgery is currently developing, though some problems still persist. One of promising solutions to the problems is application of platelet rich plasma which may accelerate soft tissue healing and bone formation. This study aims to provide basic understanding to the development of PRP application in bone healing where bone graft is applied on human maxillae. Bone defects were made on maxillae of albino rabbits, with an application of bone graft in control group and bone graft plus PRP in treatment group. Histopathological analysis was performed in both groups to assess osteoblast density and collagen tissue area. On day 21st, more osteoblast density and collagen area in treatment group are significantly observed (p<0.05, 95% confidence interval). Observations were made on hard callus formation. In conclusions, platelet rich plasma may increase density of osteoblast in rabbit maxillary bone graft.
Co-Authors Andayani, Raden Roro Rini Hanggoro Tri Rinonce Harsono, Erliana Tantri Hutagalung, Magda Rosalina Idamatussilmi, Fina Indra Wahono Ishandono Dachlan Iswinarno Doso Saputro Oktarina, Dyah Ayu Mira Rita Cempaka Rizkiani, Dwinanda Almira Satiti Retno Pudjiati Satiti Retno Pudjiati Sukasah, Chaula Luthfia Wicaksana, Aditya