Article Per Year (5 Year)
p-Index From 2020 - 2025
1.683
P-Index
This Author published in this journals
All Journal Tropical Medicine Journal Sari Pediatri Paediatrica Indonesiana JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Jurnal Gizi Klinik Indonesia Majalah Farmaseutik Medica Hospitalia Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Berita Kedokteran Masyarakat
Ida Safitri Laksanawati
Departemen Ilmu Kesehatan Anak, Fakultas Kedokteran, Kesehatan Masyarakat Dan Keperawatan Universitas Gadjah Mada/ RSUP Dr. Sardjito, Yogyakarta
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Medicine & Pharmacology Nursing Public Health

Published : 20 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 20 Documents
Search

 1   2 
Status gizi dan gambaran klinis penyakit pada pasien HIV anak awal terdiagnosis Ratni Indrawanti; Egi Arguni; Ida Safitri Laksanawati; Dwiyanti Puspitasari; Dominicus Husada
Jurnal Gizi Klinik Indonesia Vol 17, No 3 (2021): Januari
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.62154

Abstract

Nutritional status and clinical disease of HIV children patients when diagnosed for the first timeBackground: Human immunodeficiency virus (HIV) infection in children can cause nutritional problems. Currently, HIV-infected children are still diagnosed when the disease stage is advanced. Nutritional status is a marker of advanced stage conditions in HIV infection.Objective: To determine the clinical findings of disease and nutritional status of HIV children patients when diagnosed for the first time.Methods: We conducted a cross-sectional descriptive study. The data were taken from the medical record documents of child patients aged 0-18 years with the ICD 10 code B20, who was treated at the Dr. Sardjito Yogyakarta Hospital from 1 January 2004-31 December 2019. Results: There were 191 children diagnosed with HIV, 56% of them were boys. The median age was 34 months (IQR 25: 13 months, IQR 75: 69 months), and 95.5% among those were infected perinatally. There were 77 (40,3%) children who suffered from severe malnutrition and 55 (28.8%) children were moderate acute malnutrition. At the age of 0-60 months among them, there were 49 children (36.3%) suffered from severely underweight, 35 children (25.9%) underweight, 53 (39.3%) severely stunted, 38 (28.1%) stunted, 28 severely wasted (20.7%), and wasted as many as 24 (17.8%). At the age of 5-18 years old, there were 19 (33.9%) and 5 (8.9%) children who suffered from severely wasted and wasted respectively. World Health Organization (WHO) stages 3 and 4 were experienced by 62 (32.5%) and 68 (35.6%) children. As many as 41.3% of children had enlarged lymph nodes, thrush (40.8%), pneumonia (40.8%), and persistent or chronic diarrhea (21.5%). Conclusions: The nutritional status of HIV-infected children at baseline was dominated by underweight and stunted. The most clinical findings of the disease when the child was diagnosed with HIV infection were lymphadenopathy, oral thrush, pneumonia, and persistent or chronic diarrhea.
Evaluasi Luaran Klinis Terapi Antibiotika pada Pasien Anak Rawat Inap Dengan Infeksi Saluran Kemih di RSUP Dr. Sardjito Yogyakarta Widya Adhitama; Ika Puspitasari; Ida Safitri Laksanawati
Majalah Farmaseutik Vol 17, No 2 (2021)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v17i2.48803

Abstract

Infeksi Saluran Kemih (ISK) merupakan penyakit infeksi yang sering terjadi pada anak selain infeksi saluran nafas atas dan diare di negara berkembang. Salah satu terapi yang diberikan adalah antibiotik, pemilihan antibiotik harus didasarkan pola resistensi bakteri lokal. Tujuan penelitian ini untuk menilai hubungan rasionalitas antibiotik empiris terhadap luaran klinis pasien anak rawat inap dengan ISK di Rumah Sakit dr. Sardjito Yogyakarta. Penelitian ini merupakan penelitian  observasional menggunakan rancangan deskriptif-analitik dengan desain cohort retrospektif. Subyek penelitian adalah pasien anak rawat inap dengan ISK di Rumah Sakit dr. Sardjito Yogyakarta periode 1 Januari 2016 – 31 Desember 2018. Jumlah pasien yang memenuhi kriteria inklusi dan eksklusi sebanyak 63 pasien dengan 70 regimen antibiotik. Rasionalitas penggunaan antibiotik empiris dievaluasi menggunakan metode Gyssens. Hasil dari penelitian ini menunjukkan antibiotik empiris yang rasional yaitu sebesar 84,3% (59 regimen), dan yang tidak rasional sebesar 15,7% (11 regimen). Pada penggunaan antibiotik yang rasional dan memberikan luaran klinis membaik sebesar 82,9%, dan dianalisis dengan uji Fisher menunjukkan adanya hubungan yang signifikan antara rasionalitas antibiotik empiris terhadap luaran klinis pasien anak ISK dengan nilai p=0,011. Gambaran pola bakteri pada pasien ISK anak yaitu bakteri yang menginfeksi terbesar dari bakteri gram negatif (81,97%) dan bakteri gram positif sebesar 18,03%.
Evaluasi Luaran Klinis Terapi Antibiotik Pada Pasien Anak Dengan Diare di Rawat Inap RAUP Dr. Sardjito Yogyakarta Antonia Adeleide Anutopi; Ika Puspitasari; Ida Safitri Laksanawati
Majalah Farmaseutik Vol 17, No 3 (2021)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v1i1.49512

Abstract

Diare merupakan kondisi dimana terjadi frekuensi buang air besar lebih dari 3 kali dengan konsistensi feses cair. Terapi antibiotik dapat diberikan kepada pasien diare akibat infeksi. Tujuan penelitian yaitu untuk mengetahui gambaran penggunaan antibiotik empiris dan untuk mengetahui hubungan antara kesesuaian pemberian antibiotik empiris terhadap luaran klinis pada anak dengan diagnosis diare. Rancangan penelitian deskriptif-analitik dengan desain cohort retrospektif. Subyek penelitian yaitu anak dengan usia ≥2 bulan - <18 tahun yang di rawat inap di RSUP Dr. Sardjito Yogyakarta pada periode 1 Januari 2015 – 30 Juni 2019 dengan diagnosis diare persisten. Analisis data pada karakteristik subyek dilakukan secara deskriptif. Uji Chi-square digunakan untuk melihat hubungan antara kesesuaian penggunaan jenis antibiotik empiris dengan luaran klinis. Hasil penelitian menunjukkan adanya 38 pasien yang menggunakan antibiotik empiris selama periode dari 1 Januari 2015 – 30 Juni 2019. Terdapat 39 regimen yang masuk dalam kategori rasional menurut metode Gyssens. Terdapat hubungan yang signifikan antara rasionalitas penggunaan antibiotik empiris dengan luaran klinis pasien (p<0,05).  
Evaluasi Kesesuaian Dosis dan Clinical Outcome Amikasin dan Gentamisin di Bangsal Nicu (Neonatal Intensive Care Unit) RSUP Dr. Sardjito Yogyakarta Zita Dhirani Pramono; Ika Puspitasari; Ida Safitri Laksanawati
Majalah Farmaseutik Vol 17, No 3 (2021)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v1i1.58243

Abstract

Penggunaan amikasin dan gentamisin menjadi pilihan antibiotik golongan aminoglikosida dengan indeks terapi sempit dalam terapi infeksi untuk neonatus dan penggunaannya perlu diikuti dengan monitoring terapi agar dapat mencegah toksisitas terjadi. Penelitian ini bertujuan untuk mengevaluasi kesesuaian dosis amikasin dan gentamisin pasien NICU (Neonatal Intensive Care Unit) dan mengevaluasi hasil terapinya yang dilihat dari perbaikan respon klinis pasien. Penelitian ini dilakukan dengan desain cross sectional dan dilakukan penelusuran data rekam medik pasien neonatus mendapatkan terapi amikasin atau gentamisin saat menjalani rawat inap di NICU RSUP Dr. Sardjito Yogyakarta periode 1 Januari 2017 - Desember 2018. Estimasi kadar didapatkan dari dosis pemberian dan dilakukan perhitungan farmakokinetika. Clinical outcome yang diamati yakni tanda-tanda vital dan  Analisis chi square dilakukan untuk mengetahui hubungan keduanya.  Pasien yang menerima amikasin dan gentamisin mengalami clinical outcome membaik berturut-turut sebanyak 18 pasien dan 28 pasien. Analisis bivariat menunjukkan tidak ada hubungan estimasi Cmax/MIC amikasin dan gentamisin terhadap clinical outcome (p 0,05). Selain itu hasil analisis bivariat pada variabel perancu didapatkan terdapat hubungan lama infeksi dan length of stay terhadap clinical outcome. Analisis multiple logistic regression didapatkan ada hubungan length of stay terhadap clinical outcome (p =0,021).
Evaluasi Kesesuaian Dosis dan Clinical Outcome Amikasin dan Gentamisin di Picu (Pediatric Intensive Care Unit) RSUP Dr. Sardjito Yogyakarta Novrilia Atika Nabila; Ika Puspitasari; Ida Safitri Laksanawati
Majalah Farmaseutik Vol 18, No 2 (2022)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v1i1.59233

Abstract

Pemakaian amikasin dan  gentamisin yang memiliki kisaran terapi sempit perlu dilakukan monitoring terapi. Monitoring terapi dilakukan melalui tinjauan secara farmakokinetika dengan menghitung estimasi kadar. Penelitian ini bertujuan untuk melihat estimasi kadar amikasin dan gentamisin pada pasien PICU (Pediatric Intensive Care Unit) dan mengetahui hubungannya terhadap outcome klinis pasien serta kejadian nefrotoksisitas. Penelitian ini merupakan penelitian observational dengan desain cross sectional. Subjek penelitian ini adalah pasien pediatrik yang di rawat di PICU RSUP Dr. Sardjito Yogyakarta periode 2017 – 2019. Jumlah pasien yang memenuhi kriteria inklusi dan eksklusi sebanyak 54 pasien. Hasil estimasi kadar diamati berdasarkan 2 parameter PK-PD yaitu kesesuaian rasio Cmax/MIC dan Cmin>MIC. Hasil dari penelitian ini menunjukkan pada penggunaan amikasin mencapai target rasio Cmax/MIC 17 (74%), dan Cmin > MIC yaitu 3 (13%) pasien. Pada penggunaan gentamisin mencapai target rasio Cmax/MIC 16 (46%), Cmin > MIC yaitu 7 (20%) pasien. Hasil analisis dengan uji Fisher menunjukkan tidak terdapat hubungan yang signifikan kedua parameter tersebut terhadap outcome klinis dengan nilai p > 0.05. Kesesuaian estimasi kadar tidak berpengaruh secara signifikan terhadap kejadian nefrotoksisitas. Tanda-tanda nefrotoksisitas terdapat pada 3 pasien (6%).
Determinan sosial kejadian dengue shock syndrome di Semarang Yudi Pradipta; Ida Safitri Laksanawati; Dibyo Pramono
Berita Kedokteran Masyarakat (BKM) Vol 32, No 5 (2016)
Publisher : Fakultas Kedokteran Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (399.24 KB) | DOI: 10.22146/bkm.10507

Abstract

Social determinants of dengue shock syndrome in SemarangPurpose This study aimed to know the social determinants related to dengue shock syndrome.Methods This study used a case control design in Semarang. Cases were dengue patients with shock syndrome diagnosed by a clinician in the hospital, and controls were dengue patients without shock syndrome. Participants were recruited using purposive sampling, and completed written informed consent to be interviewed using a questionnaire.ResultsResults showed that children aged <18 years have the highest risk of having DSS compared to other age groups. Referral system was also correlated to dengue shock syndrome.Conclusion This study recommends the clinicians to undertake appropriate diagnosis and prompt decision making to reduce the risk of more severe DHF events. The community should improve the awareness of shock syndrome by taking their children immediately to health services for examination if they have dengue symptoms in order to get the adequate treatment.
Predictor Factors of Tuberculosis Treatment Success in Sleman Regency of Indonesia: Predictor Factors of Tuberculosis Treatment Success in Sleman Regency of Indonesia Andriyanto, Eko; Wijayanti Subronto, Yanri; Ida Safitri Laksanawati
Medica Hospitalia : Journal of Clinical Medicine Vol. 9 No. 2 (2022): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (265.462 KB) | DOI: 10.36408/mhjcm.v9i2.756

Abstract

Background : Tuberculosis (TB) is the leading cause of mortality worldwide. Several studies have created risk scores to predict treatment success in TB patients. However, cohort study did not consider other clinical forms of TB, such as negative AFB smears and extrapulmonary TB. The objectives of this study was to knowing the predictor factors for the success of TB treatment in Sleman Regency by taking into account other  clinical forms of TB such as negative smear and extrapulmonary TB. Methods : The type and design of this study was an analytical study using a cross- sectional design conducted on TB patients in Sleman Regency from 2015 – 2018. Data were collected from TB 01 or TB 03 register of the Sleman District Health Office, including age, sex, BMI at the beginning of treatment, OAT (Antituberculosis Drugs) guideline, anatomic location, initial AFB status, AFB conversion status in intensive phase, type of TB patient, and treatment outcome. Chi-Square analysis and logistic regression were used to  determine the predictors of TB treatment success. Results : The research sample was 2308 people: 2158 successful treatments and 150 patients whofailed. AFB conversion in the intensive phase was the only variable to have a role in the TB treatment success (OR = 6.655, 95% CI: 3.354–13,207, p = 0.000). Conclusion : Conversion of AFB status in the intensive phase is a variable that contributes to the success of TB treatment. Age, sex, BMI at the beginning of treatment, OAT guidelines, anatomic location, initial AFB status, and type of TB patient are not predictors of TB success.
Predictors of mortality in immunocompromised children with respiratory infections Lea Sutrisna; Rina Triasih; Ida Safitri Laksanawati
Paediatrica Indonesiana Vol 62 No 4 (2022): July 2022
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi62.4.2022.237-42

Abstract

Background Respiratory infection is a common morbidity and a major cause of mortality in immunocompromised children. Hence, identification of clinical parameters that predict mortality among immunocompromised children with respiratory infections is of importance to provide timely and appropriate intervention. Objective To determine predictors of mortality in immunocompromised children with respiratory infections. Methods We conducted a prospective cohort study of immunocompromised children aged 18 years or younger with respiratory tract infections who were admitted to Dr. Sardjito Hospital, Yogyakarta, Indonesia. All eligible children were prospectively followed up until hospital discharge. Clinical and laboratory parameters during the first 24 hours of hospitalization were collected. Results Of 79 eligible children, the overall mortality was 11 subjects (13.9%). Fever, tachycardia, tachypnea, cyanosis, leukopenia, neutropenia, thrombocytopenia, and pleural effusion were predictive factors of mortality in bivariate analysis (P<0.25). A logistic regression model showed that neutropenia (absolute neutrophil count <125/mm3) and tachycardia were the best independent predictors of mortality in immunocompromised children with respiratory infections. The children with tachycardia had 15.8 times higher probability of mortality (95%CI 5.0 to 4.4) and those with neutropenia had 8.24 times higher probability of mortality. Cyanosis and pleural effusion were also independent mortality predictors. Conclusion The risk of mortality is significantly increased in immunocompromised children with respiratory infection when tachycardia and neutropenia are also present.
Hubungan Komorbiditas Terhadap Mortalitas Pasien COVID-19 Di Rumah Sakit Pertamina Jaya Jakarta Pusat Nurhayati, Siti; Laksanawati, Ida Safitri; Pinzon, Rizaldi Taslim
Majalah Kedokteran Indonesia Vol 74 No 1 (2024): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.74.1-2024-1088

Abstract

Introduction: The COVID-19 pandemic is a disease outbreak caused by SARS-CoV-2; as of July 20, 2021, there were 2,950,058 positive cases and 76,200 deaths in Indonesia. COVID-19 patients with comorbidities are mostly hypertension (50%), diabetes mellitus (37.2%), and heart disease (16.7%). This study aims to prove how comorbidities affect the mortality of COVID-19 patients at Pertamina Jaya Hospital, Central Jakarta.Method: This study is a retrospective cohort analysis. The sample comprised 500 patients, 250 comorbid groups, and 250 without comorbidities. The secondary data source is medical records of COVID-19 patients at Pertamina Jaya Hospital from April 2020 to September 2021. Data analysis using univariate, bivariate, and multivariate.Result: Multivariate analysis with logistic regression resulted in a value of (32.197 95% CI 9.714 - 106.718) so that there is an influence on the risk of death with a comorbid history in COVID-19 patients. The relative risk value proves that hypertension has a 3-fold risk of death (3.124 95% CI 1.441 - 6.773), diabetes mellitus is 2.5 times (2.521 95% CI 1.055 - 6.024), while heart disease is 2.3 times (2.325 95% CI 1.169 - 4.622).Conclusion: Hypertension, diabetes mellitus, and heart disease are comorbidities that are predictors of mortality for COVID-19 patients due to a higher risk of death.
The frequency and distribution of pediatric healthcare-associated infections in children Murni, Indah Kartika; Wirawan, Muhammad Taufik; Patmasari, Linda; Laksanawati, Ida Safitri
Paediatrica Indonesiana Vol. 65 No. 5 (2025): September 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background Healthcare-associated infections (HAIs) are major contributors to increased morbidity, mortality, and healthcare costs. Ongoing epidemiological surveillance of nosocomial infection is needed to accurately assess their burden and inform prevention strategies. Objective To determine the frequency and distribution of HAIs. Methods A 26-month prospective cohort study (February 2016 to April 2018) was carried out at Dr Sardjito Hospital, a tertiary hospital in Indonesia, where pediatric patients hospitalized in the wards and pediatric ICU were monitored daily. HAIs were defined according to the criteria set by the Centers for Disease Control and Prevention. Results Out of 1,855 patients enrolled in the study period, 314 (16.9%) had HAI with an incidence density rate of 20.1 infections per 1,000 patient-days (416/20,672). The incidence of nosocomial urinary tract infection (UTI) was 4.3% (82/1,855) and the catheter-associated urinary tract infection (CAUTI) incidence density rate was 16.5 CAUTIs/1,000 patient-days (36/2,179). The incidence of nosocomial pneumonia, which includes both hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP), was 3.2% (59/1,885), while the specific incidence rate of VAP was 5.1 per 1,000 patient-days (14/1,359). The incidence of nosocomial bloodstream infection was 1.9% (36/1,855) and the central line-associated bloodstream infection (CLABSI) incidence rate was 4.4 CLABSIs/1,000 patient-days (5/1,121). The incidences of surgical site infection, phlebitis, nosocomial upper respiratory infection, and nosocomial gastroenteritis were 0.2% (3/1,855), 0.9% (17/1,855), 2.9% (54/1,855), and 3.4% (63/1,855), respectively. Conclusion One-sixth of children in our hospital developed HAIs, with an incidence rate of 20.1 HAI/1,000 days. The most common HAI was CAUTI, followed by VAP and CLABSI.
Co-Authors Anggy Pangaribuan Antonia Adeleide Anutopi Arguni, Egi Arif Bahiyuddin bin Badaruddin Deddy Hediyanto Desi Rusmawaningtyas Dibyo Pramono Dominicus Husada Dwiyanti Puspitasari, Dwiyanti Eggi Arguni Egi Arguni Eko Andriyanto Endy Paryanto Prawirohartono Endy Paryanto Prawirohartono Ika Puspitasari Ika Puspitasari Indah Kartika Murni Lea Sutrisna Loo Huai Na Maria Mahdalena Tri Widiyati Marshita Binti Kamarudin Milza Delfina Mohd Nasrul Bin Mohd Ghazali Mohd Nazirul Shareef bin Mohd Ridhwan Muhammad Ilham Bin Azib Novrilia Atika Nabila Patmasari, Linda Ratni Indrawanti Rina Triasih Rizaldy Pinzon Sabrina Handayani Tambun Setya Wandita Siti Nurhayati Tambun, Sabrina Handayani Umi Solekhah Intansari Widya Adhitama Wirawan, Muhammad Taufik Yanri Wijayanti Subronto Yudi Pradipta Zita Dhirani Pramono