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All Journal Jurnal Sain Veteriner Journal Physical Education, Health and Recreation
M. Zainal Arifin
Fakultas Kedokteran Hewan, Universitas Airlangga
Physics Public Health Veterinary

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Ekspresi IL – 1β pada Proses Kesembuhan Fraktur Os Femur Tikus Putih (Rattus norvegicus) Ovariektomi yang Diterapi dengan Ekstrak Cikal Tulang (Cissus quadrangularis) Ira Sari Yudaniayanti; Bambang Sektiari Lukiswanto; M. Zainal Arifin
Jurnal Sain Veteriner Vol 35, No 1 (2017): Juni
Publisher : Fakultas Kedokteran Hewan Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2018.61 KB) | DOI: 10.22146/jsv.29296

Abstract

This study aims to determine the potential of the Cissus quadrangularis extract to decreased the expression of IL-1 β so that it can to inhibit bone resorption and osteoporosis fracture healing is not delayed union. Forty rats adapted for 1 week, and then divided into four groups with 10 replications. P0 (sham-operated + Osteotomy + CMC Na); P1 (ovariectomy + Osteotomy + CMC Na); P2 (ovariectomy + Osteotomy + Raloxifene 5.4 mg /kg); P3 (ovariectomy + Osteotomy + CQ 750 mg / kg). Osteoporosis induced is made by bilateral ovariectomy in rats, then to make sure that osteoporosis is already happened, 8 weeks post-ovariectomy performed radiology examinations on the femur, then the osteotomy action. IL1-β expression observations performed in at the 2nd week and 6th week after osteotomy through the immunohistochemistry examination. The results of immunohistochemistry examination in the 2nd week showed an increased expression of IL1-β in all groups of rat that did ovariectomy (P1, P2 and P3) were significantly different (p <0.05) with a rat group that didn’t ovariectomy, as well P2 dan P3 were significantly different with P1. The Results of immunohistochemistry examination in the 6th week showed the samepattern with the 2nd week and there is increased IL1-β expression in all groups of rat compared with the results of the examination in the 2nd week. Based on these results it can be concluded that Cissus quadrangularis extract andRaloxifen can decreased the expression of IL-1 β, and the results that don’t significantly different, so that these both materials can to inhibit bone resorption and osteoporosis fracture healing don’t get delayed union.
Neuromuscular Taping Decompression Techniques Fail to Prevent Muscle Damage After Eccentric Movement Activity Muhammad Zainal Arifin; Bambang Purwanto; Damayanti Tinduh
Journal Physical Education, Health and Recreation Vol 4, No 2 (2020): April
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/pjkr.v4i1.13234

Abstract

Eccentric activity is a type of activity facilitated by the addition of one or several muscles and often leaves the effects of pain even damage to muscle cells. The study aimed to determine the effect of the application of neuromuscular taping decompression techniques to muscle damage after eccentric movement activity. The type of research conducted is experimental research with post test only with control group design. Fourteen samples were selected from non-athlete populations at SMAN 1 Driyorejo based on consecutive sampling techniques and then divided into two groups randomly. Intervention of neuromuscular taping decompression techniques was given to the treatment group before performing eccentric movement activities. The elbow shoulder-extension flexion movement by holding 9% weight in 20 seconds was chosen as the protocol of eccentric movement activity. Measuring indicators of muscle damage using a serum Ck muscle examination 6 hours after rest. The results of the independent t-test showed no significant difference in the variable of muscle damage (p> 0.05). It was concluded from this study that the neuromuscular taping decompression technique failed to prevent muscle damage after eccentric movement activity.
Co-Authors Bambang Purwanto Bambang Sektiari Lukiswanto Damayanti Tinduh Ira Sari Yudaniayanti