Reynaldo Halomoan
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Kakeksia Kardiak: Implikasi Klinis, Prevensi, dan Tatalaksana Sidhi Laksono; Reynaldo Halomoan
Jurnal Gizi Vol 9, No 2 (2020): Jurnal Gizi UNIMUS
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jg.9.2.2020.224-231

Abstract

Patients with cardiovascular diseases such as chronic heart failure may develop cardiac cachexia. This occurs due to various mechanisms associated with pathological processes in the heart. The incidence of cardiac cachexia is also a marker of poor prognosis in patients. This condition is characterized by weight loss in patients and a decrease in muscle mass. We conducted a manual search method to find the topic-related article. A total of 30 relevant works of literature were studied. We aimed to understand the role of cardiac cachexia on the physiological function and its proper management. From our study, it wasfound that systemic inflammation had a role in the development of cardiac cachexia. The presence of cardiac cachexia is associated with the disruption in several systems such as cardiovascular, gastrointestinal, and also the immune system. Strategies for prevention and appropriate management will reduce the incidence of this event. The treatment given can be pharmacological and non-pharmacological. In conclusion, cardiac cachexia impairs the functional capacity of the patient. Proper management can reduce the mortality and morbidity in patients with cardiac cachexia.Keywords: Cardiac cachexia, physiological function, preventive and management
Cryptogenic Stroke: A Challenge in Diagnosis and Management Sidhi Laksono Purwowiyoto; Budhi Setianto; Gea Panindhita; Reynaldo Halomoan; I Nyoman Wiryawan
Jurnal Kardiologi Indonesia Vol 42 No 3 (2021): Indonesian Journal of Cardiology: July - September 2021
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1149

Abstract

Ischemic stroke is responsible for 85% of all stroke globally. However, the etiology of around a quarter of ischemic stroke are undetermined, this is called cryptogenic stroke. This kind of stroke affects younger population. Several mechanism are associated with the incidence of cryptogenic stroke such as paroxysmal atrial fibrillation, patent foramen ovale, atherosclerosis, and atrial cardiopathy. Despite many advanced knowledge on stroke generally, cryptogenic stroke is still a challenge in clinical settings. To understand more about cryptogenic stroke, a new term of embolic strokes of undetermined source (ESUS) is proposed and may need a specific workup. Specific workup aims to detect any silent risk factors and also to evaluate the cardiac structure. The term of ESUS also leads to the understanding that cryptogenic stroke is highly related to embolic mechanism and anticoagulation administration might benefit the patients. However, the result of several recent studies showed that anticoagulant was not superior to antiplatelet, and antiplatelet is still the preferred treatment. Studies on PFO closure also shows different result, but the majority of the trials showed benefit of PFO closure in reducing the risk of stroke recurrence.
Diagnosis and Management of Severe Peripartum Cardiomyopathy: Diagnosis dan Manajemen Kardiomiopati Peripartum Berat Sidhi Laksono; Ananta S. Prawara; Reynaldo Halomoan
Indonesian Journal of Obstetrics and Gynecology Volume 9 No. 4 October 2021
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v9i4.1459

Abstract

Objective: To describe the diagnosis and management of severe peripartum cardiomyopathyMethods: A case report.Case: A 35-year-old woman presented with dyspnea and leg edema. The patient gave birth 3 months ago. The hemodynamic was unstable and the physical examination showed a mild rhonchi in the basal of the lung and pansystolic murmur in the apex. Echocardiography showed a dilated heart chamber and reduced ejection fraction (30%). The patient was diagnosed as severe PPCM. The initial management was to stabilize the patient using furosemide, catecholamine, and vasopressor administration. After the patient’s condition was stable, ramipril, bisoprolol, and bromocriptine were given as heart failure therapy.Conclusions: Patient with suspicion of PPCM should be managed thoroughly from detailed history taking to proper diagnostic testing such as echocardiography. Prompt treatment of severe PPCM according to the guideline will improve the cardiac function.Key words: catecholamines, echocardiography, peripartum cardiomyopathy, pregnancy, vasopressor. Abstrak Tujuan: Untuk mendeskripsikan mengenai diagnosis dan manajemen pasien pada kasus kardiomiopati peripartum yang berat.Metode: Laporan kasus.Kasus: Seorang Perempuan 35 tahun datang dengan dispnea dan edema tungkai. Pasien melahirkan 3 bulan lalu. Hemodinamik tidak stabil dan pemeriksaan fisik menunjukkan ronki ringan di basal paru dan murmur pansistolik di apeks. Ekokardiografi menunjukkan dilatasi ruang jantung dan fraksi ejeksi berkurang (30%). Pasien didiagnosis dengan PPCM berat. Penatalaksanaan awal adalah menstabilkan pasien dengan pemberian furosemid, katekolamin, dan vasopresor. Setelah kondisi pasien stabil, diberikan ramipril, bisoprolol, dan bromokriptin sebagai terapi gagal jantung.Kesimpulan: Pasien dengan kecurigaan PPCM harus dikelola secara menyeluruh mulai dari anamnesa yang rinci hingga uji diagnostik yang tepat seperti ekokardiografi. Pengobatan segera untuk PPCM derajat berat yang sesuai dengan pedoman akan meningkatkan fungsi jantung.Kata kunci: ekokardiografi, kardiomiopati peripartum, katekolamin, kehamilan, vasopressor.